2. Apoptosis Protein Tyrosine Kinase/RTK
  3. Apoptosis c-Met/HGFR
  4. 1147271-25-7

1147271-25-7

JNJ-40255293 Chemical Structure

1147271-25-7

Chemical Structure

  • JNJ-40255293
  • CAS No: 1147271-25-7
    Formula: C23H22N4O3
    Molecular Weight: 402.45
  • IUPAC Name: 2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one
  • InChIKey: BCDASHXLAMCATI-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(C=C(C=C2)OCCN3CCOCC3)C4=NC(N)=NC(C5=CC=CC=C5)=C41

Biological Activity: JNJ-40255293 is a high-affinity human A 2A receptor antagonist with a KiKi of 7.5 nM. JNJ-40255293 can be used in the research of neurodegenerative diseases such as Parkinson's disease[1].

Cat. No. Product Name Purity Description
HY-122105 JNJ-40255293 JNJ-40255293 is a high-affinity human A 2A receptor antagonist with a KiKi of 7.5 nM. JNJ-40255293 can be used in the research of neurodegenerative diseases such as Parkinson's disease.

References

[1]. John R Atack, et al. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease. ACS Chem Neurosci. 2014 Oct 15;5(10):1005-19.  [Content Brief]

Keywords:

JNJ-40255293