2. Anti-infection
  3. Bacterial
  4. 2680554-46-3

2680554-46-3

PXYD3 Chemical Structure

2680554-46-3

Chemical Structure

  • PXYD3
  • CAS No: 2680554-46-3
    Formula: C25H21NO5
    Molecular Weight: 415.44
  • IUPAC Name: 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-N-(3-methylbenzyl)acetamide
  • InChIKey: FEEMGPHIWVTBJI-UHFFFAOYSA-N
  • SMILES: CC1=CC=CC(CNC(COC2=CC3=C(C(O)=C2)C(C=C(O3)C4=CC=CC=C4)=O)=O)=C1

Biological Activity: PXYD3 is a ribosomal protein S1 (RpsA) antagonist with Kds of 5.66 and 6.91 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb)[1].

Cat. No. Product Name Purity Description
HY-146448 PXYD3 PXYD3 is a ribosomal protein S1 (RpsA) antagonist with Kds of 5.66 and 6.91 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb).

References

[1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant <i>Mycobacterium Tuberculosis</i>. Eur J Med Chem. 2020 Jun 15;196:112317. [Content Brief]

Keywords:

PXYD3