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228544-65-8

VULM 1457 Chemical Structure

228544-65-8

Chemical Structure

  • VULM 1457
  • CAS No: 228544-65-8
    Formula: C25H27N3O3S
    Molecular Weight: 449.57
  • IUPAC Name: 1-(2,6-diisopropylphenyl)-3-(4-((4-nitrophenyl)thio)phenyl)urea
  • InChIKey: XFFITGBWVLQNCD-UHFFFAOYSA-N
  • SMILES: O=C(NC1=CC=C(SC2=CC=C([N+]([O-])=O)C=C2)C=C1)NC3=C(C=CC=C3C(C)C)C(C)C

Biological Activity: VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].

Cat. No. Product Name Purity Description
HY-107571 VULM 1457 99.71% VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia.

References

Keywords:

VULM 1457