2. Immunology/Inflammation
  3. COX
  4. 2826264-81-5

2826264-81-5

Pulixin Chemical Structure

2826264-81-5

Chemical Structure

  • Pulixin
  • CAS No: 2826264-81-5
    Formula: C14H11NO4
    Molecular Weight: 257.24
  • IUPAC Name: 3-amino-7,9-dihydroxy-1-methyl-6H-benzo[c]chromen-6-one
  • InChIKey: KAASRWALAPIHNZ-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C

Biological Activity: Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM[1].

Cat. No. Product Name Purity Description
HY-N10197 Pulixin Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.

References

[1]. Niu G, et al. A novel fungal metabolite inhibits Plasmodium falciparum transmission and infection. Parasit Vectors. 2021;14(1):177. Published 2021 Mar 24. [Content Brief]

Keywords:

Pulixin