1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  2. RAR/RXR
  3. 877606-63-8

877606-63-8

Afacifenacin Chemical Structure

877606-63-8

Chemical Structure

  • Afacifenacin
  • Synonym(s): SMP-986
  • CAS No: 877606-63-8
    Formula: C27H26F3N3O2
    Molecular Weight: 481.51
  • IUPAC Name: (S)-4-phenyl-3-(1-(3-(trifluoromethoxy)benzyl)piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one
  • InChIKey: IJUMFEAYOMCXAQ-VWLOTQADSA-N
  • SMILES: O=C1NC2=C(C=CC=C2)[C@H](C3=CC=CC=C3)N1C4CCN(CC5=CC=CC(OC(F)(F)F)=C5)CC4

Biological Activity: Afacifenacin (SMP-986) is a potent and orally active muscarinic receptor antagonist. Afacifenacin inhibits the bladder afferent pathway through the sodium-channel blockade, increasing volume, and reducing the frequency of urination and incontinence. Afacifenacin has the potential for the research of overactive bladder (OAB)[1][2].

Cat. No. Product Name Purity Description
HY-14828 Afacifenacin Afacifenacin (SMP-986) is a potent and orally active muscarinic receptor antagonist. Afacifenacin inhibits the bladder afferent pathway through the sodium-channel blockade, increasing volume, and reducing the frequency of urination and incontinence. Afacifenacin has the potential for the research of overactive bladder (OAB).

References

Keywords:

Afacifenacin