2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. 16265-56-8

16265-56-8

6-Deoxyjacareubin Chemical Structure

16265-56-8

Chemical Structure

  • 6-Deoxyjacareubin
  • CAS No: 16265-56-8
    Formula: C18H14O5
    Molecular Weight: 310.30
  • IUPAC Name: 5,10-dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one
  • InChIKey: NHNIESSJWQBRJW-UHFFFAOYSA-N
  • SMILES: O=C1C2=C(OC3=C1C=CC=C3O)C=C4C(C=CC(C)(C)O4)=C2O

Biological Activity: 6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS)[1].

Cat. No. Product Name Purity Description
HY-N2707 6-Deoxyjacareubin ≥98.0% 6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS).

References

[1]. Hoshino T, et al. 6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis. Neurosci Res. 2021 Feb;163:43-51. [Content Brief]

Keywords:

6-Deoxyjacareubin