2. Apoptosis Metabolic Enzyme/Protease
  3. Apoptosis Endogenous Metabolite
  4. 141-05-9

141-05-9

Diethyl maleate Chemical Structure

141-05-9

Chemical Structure

  • Diethyl maleate
  • Synonym(s): Maleic acid diethyl ester
  • CAS No: 141-05-9
    Formula: C8H12O4
    Molecular Weight: 172.18
  • IUPAC Name: diethyl maleate
  • InChIKey: IEPRKVQEAMIZSS-WAYWQWQTSA-N
  • SMILES: O=C(OCC)/C=C\C(OCC)=O

Biological Activity: Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells[1].

Cat. No. Product Name Purity Description
HY-Y1147 Diethyl maleate 98.66% Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells.

References

[1]. Andrea Gille, et al. Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate. Redox Biol. 2019 Jan;20:19-27. [Content Brief]

Keywords:

Diethyl maleate