2. Natural Products
  3. Plants Alkaloids
  4. Apocynaceae
  5. Alstonia macrophylla Wall. ex G. Don
  6. 505-75-9

505-75-9

Cicutoxin Chemical Structure

505-75-9

Chemical Structure

  • Cicutoxin
  • CAS No: 505-75-9
    Formula: C17H22O2
    Molecular Weight: 258.36
  • SMILES: OCCCC#CC#C/C=C/C=C/C=C/[C@H](O)CCC

Biological Activity: Cicutoxin is a convulsant. Cicutoxin blocks Na+ and K+ channels and inhibits γ-aminobutyric acid pathways. Cicutoxin is a potent GABA antagonist that induces recurrent seizures and exerts cholinergic effects. Cicutoxin acts primarily on the brain and skeletal muscles. Cicutoxin can be isolated from Cicuta maculata (water hemlock) and Cicuta douglasii[1].

Cat. No. Product Name Purity Description
HY-D0446 C.I. Acid orange 33 C.I. Acid orange 33 is an acidic orange-yellow dye that can be adsorbed and removed by bentone.

References

[1]. Uwai K, et al. Exploring the structural basis of neurotoxicity in C(17)-polyacetylenes isolated from water hemlock. J Med Chem. 2000 Nov 16;43(23):4508-15. [Content Brief]

Keywords:

Cicutoxin