2. Cell Cycle/DNA Damage Apoptosis
  3. CDK Apoptosis
  4. 959-24-0

959-24-0

Sotalol hydrochloride Chemical Structure

959-24-0

Chemical Structure

  • Sotalol hydrochloride
  • Synonym(s): MJ 1999
  • CAS No: 959-24-0
    Formula: C12H21ClN2O3S
    Molecular Weight: 308.82
  • IUPAC Name: N-(4-(1-hydroxy-2-(isopropylamino)ethyl)phenyl)methanesulfonamide hydrochloride
  • InChIKey: VIDRYROWYFWGSY-UHFFFAOYSA-N
  • SMILES: OC(C1=CC=C(NS(C)(=O)=O)C=C1)CNC(C)C.Cl

Biological Activity: Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3].

Cat. No. Product Name Purity Description
HY-B0437R Sotalol (hydrochloride) (Standard) ≥98% Sotalol (hydrochloride) (Standard) is the analytical standard of Sotalol (hydrochloride). This product is intended for research and analytical applications. Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent.
HY-B0437 Sotalol hydrochloride 99.91% Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent.
HY-B0437AS Sotalol-d6 hydrochloride ≥99.0% Sotalol-d6 (hydrochloride) is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels.
HY-B0437S Sotalol-d6 Sotalol-d6 is the deuterium labeled Sotalol. Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent.

References

[1]. Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369(1):152-162. [Content Brief]
[2]. Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38(7):1450-1455. [Content Brief]
[3]. Kinga K Borowicz-Reutt, et al. Sotalol does not interfere with the antielectroshock action of selected second-generation antiepileptic drugs in mice.Pharmacol Rep. 2021 Apr;73(2):516-524. [Content Brief]

Keywords:

Sotalol (hydrochloride) (Standard)Sotalol hydrochlorideSotalol-d6 hydrochlorideSotalol-d6