2. Apoptosis Metabolic Enzyme/Protease
  3. Apoptosis Endogenous Metabolite
  4. 499-80-9

499-80-9

2,4-PDCA Chemical Structure

499-80-9

Chemical Structure

  • 2,4-PDCA
  • CAS No: 499-80-9
    Formula: C7H5NO4
    Molecular Weight: 167.12
  • IUPAC Name: pyridine-2,4-dicarboxylic acid
  • InChIKey: MJIVRKPEXXHNJT-UHFFFAOYSA-N
  • SMILES: O=C(C1=NC=CC(C(O)=O)=C1)O

Biological Activity: 2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenase, including JmjC domain-containing family of histone demethylases (JHDMs). 2,4-PDCA is a target chemical in the field of bio-based plastics[1][2][3].

Cat. No. Product Name Purity Description
HY-W017132 2,4-PDCA 99.80% 2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenase, including JmjC domain-containing family of histone demethylases (JHDMs). 2,4-PDCA is a target chemical in the field of bio-based plastics.

References

[1]. Brewitz L, et al. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases. J Fluor Chem. 2021 Jul;247:109804. [Content Brief]
[2]. Gómez-Álvarez H, et al. Bioconversion of lignin-derived aromatics into the building block pyridine 2,4-dicarboxylic acid by engineering recombinant Pseudomonas putida strains. Bioresour Technol. 2022 Feb;346:126638. [Content Brief]
[3]. Hanauske-Abel HM. Prolyl 4-hydroxylase, a target enzyme for drug development. Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors. J Hepatol. 1991;13 Suppl 3:S8-15; discussion S16. [Content Brief]

Keywords:

2,4-PDCA