2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. 6265-56-1

6265-56-1

MHY 553 Chemical Structure

6265-56-1

Chemical Structure

  • MHY 553
  • CAS No: 6265-56-1
    Formula: C13H9NO2S
    Molecular Weight: 243.28
  • IUPAC Name: 4-(benzo[d]thiazol-2-yl)benzene-1,3-diol
  • InChIKey: YQIRLDMXXRINIJ-UHFFFAOYSA-N
  • SMILES: OC1=CC=C(C2=NC3=CC=CC=C3S2)C(O)=C1

Biological Activity: MHY 553 is a PPARα agonist that is effective when taken orally. MHY 553 helps alleviate liver fat accumulation by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY 553 inhibits the accumulation of triglycerides induced by liver X receptor agonists in HepG2 cells. MHY 553 significantly suppresses the expression of inflammatory mRNA in aging rats[1].

Cat. No. Product Name Purity Description
HY-128135 MHY 553 MHY 553 is a PPARα agonist that is effective when taken orally. MHY 553 helps alleviate liver fat accumulation by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY 553 inhibits the accumulation of triglycerides induced by liver X receptor agonists in HepG2 cells. MHY 553 significantly suppresses the expression of inflammatory mRNA in aging rats.

References

[1]. Seong Min Kim, et al. Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget. 2017 May 8;8(28):46273–46285.

Keywords:

MHY 553