2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. 65321-41-7

65321-41-7

MK-761 free base Chemical Structure

65321-41-7

Chemical Structure

  • MK-761 free base
  • CAS No: 65321-41-7
    Formula: C13H19N3O2
    Molecular Weight: 249.31
  • IUPAC Name: (S)-2-(3-(tert-butylamino)-2-hydroxypropoxy)nicotinonitrile
  • InChIKey: KVTGTAZVDSYIPY-NSHDSACASA-N
  • SMILES: N#CC1=CC=CN=C1OC[C@H](CNC(C)(C)C)O

Biological Activity: MK-761 free base is a potent and orally active β2-adrenergic blocker. MK-761 free base shows antihypertensive and positive inotropic effects. MK-761 free base shows vasodilating properties[1].

References

[1]. Scriabine A, et al. Antihypertensive and cardiac effects of two novel beta-adrenoceptor blocking drugs. Experientia. 1979 Dec 15;35(12):1634-7. [Content Brief]

Keywords:

MK-761 free base