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  4. 1210-34-0

1210-34-0

Dibenzosuberol Chemical Structure

1210-34-0

Chemical Structure

  • Dibenzosuberol
  • CAS No: 1210-34-0
    Formula: C15H14O
    Molecular Weight: 210.27
  • IUPAC Name: 10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ol
  • InChIKey: POAVRNPUPPJLKZ-UHFFFAOYSA-N
  • SMILES: OC1C2=CC=CC=C2CCC3=CC=CC=C31

Biological Activity: Dibenzosuberol (Compound 2) is a key intermediate in the synthesis of compounds associated with inhibiting Trypanosoma thiol reductase (TryR). Dibenzosuberol also shows inhibition of T. brucei with an EC50 value of 51.3 μM. Dibenzosuberol is also an impurity of Amitriptyline (HY-B0527)[1].

Cat. No. Product Name Purity Description
HY-W043676 Dibenzosuberol Dibenzosuberol (Compound 2) is a key intermediate in the synthesis of compounds associated with inhibiting Trypanosoma thiol reductase (TryR). Dibenzosuberol also shows inhibition of T. brucei with an EC50 value of 51.3 μM. Dibenzosuberol is also an impurity of Amitriptyline (HY-B0527).

References

[1]. Richardson JL, et al. Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis. ChemMedChem. 2009 Aug;4(8):1333-40. [Content Brief]

Keywords:

Dibenzosuberol