2. Anti-infection
  3. Beta-lactamase
  4. 49676-35-9

49676-35-9

OX01914 Chemical Structure

49676-35-9

Chemical Structure

  • OX01914
  • CAS No: 49676-35-9
    Formula: C17H14N4O
    Molecular Weight: 290.32
  • IUPAC Name: 4,6-diphenylpyrimidine-2-carbohydrazide
  • InChIKey: WQLVMRVQMYSEQZ-UHFFFAOYSA-N
  • SMILES: O=C(NN)C1=NC(C2=CC=CC=C2)=CC(C3=CC=CC=C3)=N1

Biological Activity: OX01914 is a water-solube and permeable utrophin modulator (upregulates utrophin protein levels), with an EC50 of 20.5 μM. OX01914 can be used in study of duchenne muscular dystrophy (DMD)[1].

Cat. No. Product Name Purity Description
HY-N15020 Izumenolide Izumenolide is found in the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC50 concentration of TEM-2 β-lactamase was 0.01 μg/mL.

References

[1]. Vuorinen A, et al. Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. Eur J Med Chem. 2021 Aug 5;220:113431. [Content Brief]

Keywords:

OX01914