2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. 251970-28-2

251970-28-2

PAMAM dendrimer G1.5 carboxylate sodium Chemical Structure

251970-28-2

Chemical Structure

  • PAMAM dendrimer G1.5 carboxylate sodium
  • Synonym(s): PAMAM G1.5 carboxylate sodium
  • CAS No: 251970-28-2
    Formula: C110H176N26Na16O44
    Molecular Weight: 2934.56
  • InChIKey: KKDVRAVJOOYSGF-UHFFFAOYSA-A
  • SMILES: O=C(CCN(CCC(O[Na])=O)CCNC(CCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCNC(CCN(CCN(CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)=O)=O)O[Na]

Biological Activity: PAMAM dendrimer G1.5 carboxylate (PAMAM G1.5 carboxylate) sodium is a polyanionic dendrimers comprising the terminal groups sodium carboxylate. PAMAM dendrimer G1.5 carboxylate shows antiviral activity with the MERS‐CoV plaque inhibition assay, with the inhibition rate of 40.5%[1].

Cat. No. Product Name Purity Description
HY-169047 PAMAM dendrimer G1.5 carboxylate sodium PAMAM dendrimer G1.5 carboxylate (PAMAM G1.5 carboxylate) sodium is a polyanionic dendrimers comprising the terminal groups sodium carboxylate. PAMAM dendrimer G1.5 carboxylate shows antiviral activity with the MERS‐CoV plaque inhibition assay, with the inhibition rate of 40.5%.

References

[1]. Cláudia Camacho, et al. Use of Half-Generation PAMAM Dendrimers (G0.5–G3.5) with Carboxylate End-Groups to Improve the DACHPtCl2 and 5-FU Efficacy as Anticancer Drugs. Molecules. 2021 May 14;26(10):2924. [Content Brief]

Keywords:

PAMAM dendrimer G1.5 carboxylate sodium