2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. Casein kinase 1δ-IN-9

Casein kinase 1δ-IN-9 (compound 737) is a potent casein kinase 1δ (CK1δ/CK15) inhibitor. Casein kinase 1δ-IN-9 can be used for the research of neurodegenerative disorders such as Alzheimer's disease.

For research use only. We do not sell to patients.

Casein kinase 1δ-IN-9 Chemical Structure

Casein kinase 1δ-IN-9 Chemical Structure

CAS No. : 854355-54-7

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1 mg USD 180 In-stock
5 mg USD 420 In-stock
10 mg USD 630 In-stock
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Based on 1 publication(s) in Google Scholar

Casein kinase 1δ-IN-9 Related Antibodies

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Description

Casein kinase 1δ-IN-9 (compound 737) is a potent casein kinase 1δ (CK1δ/CK15) inhibitor. Casein kinase 1δ-IN-9 can be used for the research of neurodegenerative disorders such as Alzheimer's disease[1].

IC50 & Target

CK1δ

 

Molecular Weight

269.73

Formula

C15H12ClN3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC2=NC=CC(NCC3=NC=CC=C3)=C2C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (370.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7074 mL 18.5371 mL 37.0741 mL
5 mM 0.7415 mL 3.7074 mL 7.4148 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7074 mL 18.5371 mL 37.0741 mL 92.6853 mL
5 mM 0.7415 mL 3.7074 mL 7.4148 mL 18.5371 mL
10 mM 0.3707 mL 1.8537 mL 3.7074 mL 9.2685 mL
15 mM 0.2472 mL 1.2358 mL 2.4716 mL 6.1790 mL
20 mM 0.1854 mL 0.9269 mL 1.8537 mL 4.6343 mL
25 mM 0.1483 mL 0.7415 mL 1.4830 mL 3.7074 mL
30 mM 0.1236 mL 0.6179 mL 1.2358 mL 3.0895 mL
40 mM 0.0927 mL 0.4634 mL 0.9269 mL 2.3171 mL
50 mM 0.0741 mL 0.3707 mL 0.7415 mL 1.8537 mL
60 mM 0.0618 mL 0.3090 mL 0.6179 mL 1.5448 mL
80 mM 0.0463 mL 0.2317 mL 0.4634 mL 1.1586 mL
100 mM 0.0371 mL 0.1854 mL 0.3707 mL 0.9269 mL
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Casein kinase 1δ-IN-9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Casein kinase 1δ-IN-9854355-54-7Casein KinaseInhibitorinhibitorinhibit

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