Cathepsin E substrate e 

Cathepsin E substrate e is a substrate of Cathepsin E. Cathepsin E substrate e was designed in such a way that due to the close proximity of a Mca-donor and a Dnp-acceptor, a near complete intramolecular quenching effect was achieved in its intact state. After the proteolytic cleavage of the hydrophobic motif of the peptide substrate, both Mca and Dnp would be further apart, resulting in bright fluorescence^[1].

1327.40

C₆₁H₈₂N₁₆O₁₈

1246741-19-4

{Mca}-Ala-Gly-Phe-Ser-Leu-Pro-Ala-{Lys(Dnp)}-{d-Arg}-NH2

{Mca}-AGFSLPA-{Lys(Dnp)}-{d-Arg}-NH2

O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)CO)=O)CC(C)C)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](CCCNC(N)=N)C(N)=O)=O)CCCCNC5=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C5)=O)C)=O)CCC4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.