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  3. Biochemical Assay Reagents
  4. CDAP

CDAP is an organic cyanylating reagent that can be used for preparation of solid phase affinity reagents, modification of protein thiols and nucleotide delivery. CDAP also activates polysaccharides with a variety of chemical properties. CDAP can be used to prepare conjugate vaccines and other immune reagents.

For research use only. We do not sell to patients.

CDAP Chemical Structure

CDAP Chemical Structure

CAS No. : 59016-56-7

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Based on 1 publication(s) in Google Scholar

CDAP Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

CDAP is an organic cyanylating reagent that can be used for preparation of solid phase affinity reagents, modification of protein thiols and nucleotide delivery. CDAP also activates polysaccharides with a variety of chemical properties. CDAP can be used to prepare conjugate vaccines and other immune reagents[1].

In Vitro

CDAP can be used to activate a broad range of acidic, neutral and other classes of polysaccharides, which can then be clerivatized with diamines, dihydrazides or other functional groups in preparation for coupling to proteins[1].
Proteins can be directly conjugated to CDAP-activated polysaccharides, without the need for additional spacer molecules, thereby simplifying the preparation of conjugate vaccines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CDAP Related Antibodies
Molecular Weight

234.99

Formula

C8H10BF4N3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)C1=CC=[N+](C=C1)C#N.F[B-](F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (425.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2554 mL 21.2772 mL 42.5545 mL
5 mM 0.8511 mL 4.2554 mL 8.5109 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.93%

SDS (476 KB)

COA (242 KB) HNMR (127 KB) LCMS (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2554 mL 21.2772 mL 42.5545 mL 106.3861 mL
5 mM 0.8511 mL 4.2554 mL 8.5109 mL 21.2772 mL
10 mM 0.4255 mL 2.1277 mL 4.2554 mL 10.6386 mL
15 mM 0.2837 mL 1.4185 mL 2.8370 mL 7.0924 mL
20 mM 0.2128 mL 1.0639 mL 2.1277 mL 5.3193 mL
25 mM 0.1702 mL 0.8511 mL 1.7022 mL 4.2554 mL
30 mM 0.1418 mL 0.7092 mL 1.4185 mL 3.5462 mL
40 mM 0.1064 mL 0.5319 mL 1.0639 mL 2.6597 mL
50 mM 0.0851 mL 0.4255 mL 0.8511 mL 2.1277 mL
60 mM 0.0709 mL 0.3546 mL 0.7092 mL 1.7731 mL
80 mM 0.0532 mL 0.2660 mL 0.5319 mL 1.3298 mL
100 mM 0.0426 mL 0.2128 mL 0.4255 mL 1.0639 mL
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CDAP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDAP59016-56-7Biochemical Assay Reagentscyanylating reagentsolid phase affinity reagentsprotein thiolsnucleotidevaccinesInhibitorinhibitorinhibit

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