2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK2/Bcl2-IN-1

CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells.

For research use only. We do not sell to patients.

CDK2/Bcl2-IN-1 Chemical Structure

CDK2/Bcl2-IN-1 Chemical Structure

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CDK2/Bcl2-IN-1 Related Antibodies

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Description

CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells[1].

IC50 & Target

IC50: 117.6 nM (CDK2)[1]
Molecular Weight

668.88

Formula

C35H56O10S
SMILES

CC1=CC[C@@]2(C(O[C@@H]3[C@@H](OS(=O)(O)=O)[C@H](O)[C@H](O)CO3)=O)CC[C@@]4(C)[C@]5(C)CCC6C(C)(C)[C@@H](O)CC[C@]6(C)C5CCC4C2[C@H]1C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDK2/Bcl2-IN-1 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK2/Bcl2-IN-1CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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