2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK8-IN-5

CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease.

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CDK8-IN-5 Chemical Structure

CDK8-IN-5 Chemical Structure

CAS No. : 2855087-10-2

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CDK8-IN-5 Related Antibodies

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Description

CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease[1].

IC50 & Target[1]

CDK8

72 nM (IC50)

Molecular Weight

426.46

Formula

C26H22N2O4
CAS No.
SMILES

O=C(C1=CC=C(C=C1)C2=CC(OC(C3=CC=CC=C3)=C4)=C(C(O)=C2)C4=O)N5CCNCC5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDK8-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK8-IN-52855087-10-2CDKCyclin dependent kinaseIL-10inflammatory bowel diseaseanti-inflammatoryInhibitorinhibitorinhibit

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