2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK9-IN-9

CDK9-IN-9 (example 2) is a potent and selective CDK9 inhibitor with an IC50 of 1.8 nM. CDK9-IN-9 inhibits CDK2 with an IC50 of 155 nM. CDK9-IN-9 has anti-cancer activity.

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CDK9-IN-9 Chemical Structure

CDK9-IN-9 Chemical Structure

CAS No. : 2246956-84-1

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CDK9-IN-9 Related Antibodies

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Description

CDK9-IN-9 (example 2) is a potent and selective CDK9 inhibitor with an IC50 of 1.8 nM. CDK9-IN-9 inhibits CDK2 with an IC50 of 155 nM. CDK9-IN-9 has anti-cancer activity[1].

IC50 & Target[1]

CDK9

1.8 nM (IC50)

CDK2

155 nM (IC50)

In Vitro

CDK9-IN-9 (example 2) inhibits the proliferation of HeLa, HeLa-MaTu-ADR, NCI-H460, DU145, Caco-2, B16F10, A2780 and MOLM-13 cells with IC50s of 4.4 nM, 5.3 nM, 9.2 nM, 4.5 nM, 8.4 nM, 1.2 nM, 1.2 nM, 2.0 nM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CDK9-IN-9 Related Antibodies
Molecular Weight

459.51

Formula

C22H23F2N5O2S
CAS No.
SMILES

CS(CC1=CC2=CC(NC3=NC=C(C(C4=CC=C(C(NCCCCO2)=C4)F)=N3)F)=C1)(=O)=N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDK9-IN-9 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK9-IN-92246956-84-1CDKCyclin dependent kinaseCDK9CDK2anti-canceractivityInhibitorinhibitorinhibit

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