Cefalonium

Cat. No.: HY-B1252: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci.

For research use only. We do not sell to patients.

Cefalonium Chemical Structure

CAS No. : 5575-21-3

Size	Price	Stock
5 mg	USD 30	Ask For Quote & Lead Time
10 mg	USD 50	Ask For Quote & Lead Time
25 mg	USD 100	Ask For Quote & Lead Time
50 mg	USD 160	Ask For Quote & Lead Time
100 mg	USD 260	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Cefalonium:

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci^[1]^[2]^[3].

IC₅₀ & Target

β-lactam

Molecular Weight

458.51

Formula

C₂₀H₁₈N₄O₅S₂

CAS No.

5575-21-3

SMILES

O=C(N[C@H]1[C@@]2([H])SCC(C[N+]3=CC=C(C(N)=O)C=C3)=C(C([O-])=O)N2C1=O)CC4=CC=CS4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (272.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1810 mL	10.9049 mL	21.8098 mL
5 mM	0.4362 mL	2.1810 mL	4.3620 mL
10 mM	0.2181 mL	1.0905 mL	2.1810 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Harada K, et, al. Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis. Antibiotics (Basel). 2020 Apr 21;9(4):197. [Content Brief]

[2]. Demon D, et, al. The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. Vet Microbiol. 2012 Nov 9;160(1-2):141-50. [Content Brief]

[3]. Berry EA, et, al. Effect of an intramammary teat seal and dry cow antibiotic in relation to dry period length on postpartum mastitis. J Dairy Sci. 2007 Feb;90(2):760-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1810 mL	10.9049 mL	21.8098 mL	54.5244 mL
	5 mM	0.4362 mL	2.1810 mL	4.3620 mL	10.9049 mL
	10 mM	0.2181 mL	1.0905 mL	2.1810 mL	5.4524 mL
	15 mM	0.1454 mL	0.7270 mL	1.4540 mL	3.6350 mL
	20 mM	0.1090 mL	0.5452 mL	1.0905 mL	2.7262 mL
	25 mM	0.0872 mL	0.4362 mL	0.8724 mL	2.1810 mL
	30 mM	0.0727 mL	0.3635 mL	0.7270 mL	1.8175 mL
	40 mM	0.0545 mL	0.2726 mL	0.5452 mL	1.3631 mL
	50 mM	0.0436 mL	0.2181 mL	0.4362 mL	1.0905 mL
	60 mM	0.0363 mL	0.1817 mL	0.3635 mL	0.9087 mL
	80 mM	0.0273 mL	0.1363 mL	0.2726 mL	0.6816 mL
	100 mM	0.0218 mL	0.1090 mL	0.2181 mL	0.5452 mL

Cefalonium Related Classifications

Inflammation/Immunology Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefalonium5575-21-3AntibioticBacterialfirst-generationβ-lactamcephalosporinantibioticbovinemastitisGram-positivebacteriastaphylococciInhibitorinhibitorinhibit

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