2. Anti-infection
  3. Antibiotic Bacterial
  4. Cefmenoxime

Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.

For research use only. We do not sell to patients.

Cefmenoxime Chemical Structure

Cefmenoxime Chemical Structure

CAS No. : 65085-01-0

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Cefmenoxime Related Antibodies

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Description

Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cefmenoxime (SCE-1365) inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae[1].
Cefmenoxime (SCE-1365) inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus[1].
Cefmenoxime (SCE-1365) against Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cefmenoxime Related Antibodies
In Vivo

Cefmenoxime (SCE-1365) (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Jcl:ICR mice[2]
Dosage: 40 mg/kg
Administration: Subcutaneous injection; daily, for 7 days
Result: Inhibited mortality rate of animals was 60% at a dose of 40 mg/kg.
Molecular Weight

511.56

Formula

C16H17N9O5S3
CAS No.
SMILES

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cefmenoxime Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefmenoxime65085-01-0SCE-1365SCE1365SCE 1365AntibioticBacterialCephalosporinantibacterialgram-positivegram-negativeInhibitorinhibitorinhibit

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