2. Anti-infection
  3. Antibiotic Bacterial
  4. Cephaloridine

Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Cephaloridine hydrate) usually boasts enhanced water solubility and stability.

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Cephaloridine Chemical Structure

Cephaloridine Chemical Structure

CAS No. : 50-59-9

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Other Forms of Cephaloridine:

Cephaloridine Related Antibodies

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Description

Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cephaloridine can inhibit Staphylococcus aureus penicillin-sensitive strains, penicillin-resistant strains, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Clostridium septicum, and so on, with MICs of 0.05-1 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cephaloridine Related Antibodies
In Vivo

Cephaloridine (50-500 mg/kg; i.m.) exhibits dose-related nephrotoxicity in rabbits and monkeys[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rabbits and monkeys[2]
Dosage: 50, 100, 200 and 500 mg/kg
Administration: i.m.
Result: Resulted in marked alteration in renal function and necrosis of proximal tubules at 200 and 500 mg/kg.
Did not appear to cause renal injury at 50 and 100 mg/kg.
Molecular Weight

415.49

Formula

C19H17N3O4S2
CAS No.
SMILES

O=C(C(N12)=C(C[N+]3=CC=CC=C3)CS[C@]2([H])[C@H](NC(CC4=CC=CS4)=O)C1=O)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cephaloridine Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cephaloridine50-59-9AntibioticBacterialantibacterialbroad-spectrumStaphylococcusCorynebacteriumClostridiumnephrotoxicityInhibitorinhibitorinhibit

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