Cephapirin (Synonyms: Cefapirin)

Cat. No.: HY-A0153: FAQs
Data Sheet Handling Instructions

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Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Cephapirin sodium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Cephapirin Chemical Structure

CAS No. : 21593-23-7

Size	Price	Stock
1 mg	USD 40	Ask For Quote & Lead Time
5 mg	USD 152	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Cephapirin:

Cephapirin sodium

Other Forms of Cephapirin:

Cephapirin sodium In-stock

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Biological Activity
Purity & Documentation
References
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Description

Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity^[1]^[2]^[3].

IC₅₀ & Target

β-lactam

In Vitro

Cephapirin (Cefapirin) inhibits Staphylococcus aureus by cephapirin concentrations of 0.09 to 12.5 mug/mL^[2].
Cephapirin (Cefapirin) inhibits S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia isolates by less than 1 mug/mL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cephapirin (Cefapirin) (200 mg; i.m.;cows) is effective for cows infected with S. aureus^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

423.46

Formula

C₁₇H₁₇N₃O₆S₂

CAS No.

21593-23-7

SMILES

O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(CSC3=CC=NC=C3)=O)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bran JL, et al. Clinical and in vitro evaluation of cephapirin, a new cephalosporin antibiotic. Antimicrob Agents Chemother. 1972 Jan;1(1):35-40. [Content Brief]

[2]. Axelrod J, et, al. Cephapirin: in vitro antibacterial spectrum. Appl Microbiol. 1971 Nov;22(5):904-8. [Content Brief]

[3]. Roy JP, et, al. Efficacy of a 5-day extended therapy program during lactation with cephapirin sodium in dairy cows chronically infected with Staphylococcus aureus. Can Vet J. 2009 Dec;50(12):1257-62.

Cephapirin Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cephapirin21593-23-7CefapirinAntibioticBacterialephalosporinantibioticStaphylococcus aureusInhibitorinhibitorinhibit

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