2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Antibiotic TOPK
  4. Cephradine monohydrate

Cephradine monohydrate  (Synonyms: Cefradine monohydrate)

Cat. No.: HY-128449
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Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.

For research use only. We do not sell to patients.

Cephradine monohydrate Chemical Structure

Cephradine monohydrate Chemical Structure

CAS No. : 75975-70-1

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Cephradine monohydrate Related Antibodies

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Description

Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK[1][2][3].

IC50 & Target

β-lactam

 

In Vitro

Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 µg/mL at both pH 7.4 and pH 5.5[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cephradine monohydrate Related Antibodies
In Vivo

Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Nondiabetic mice
Dosage: 25 mg/kg
Administration: S.c.; 11 days
Result: Reduced the bacterial density and counts in the abscesses.
Clinical Trial
Molecular Weight

367.42

Formula

C16H21N3O5S
CAS No.
SMILES

O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CCC=CC3)=O)C1=O)O.[H]O[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cephradine monohydrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cephradine75975-70-1CefradineBacterialAntibioticTOPKT-LAK cell-originated protein kinaseOralGrampositiveGram-negativeGenitourinaryGastrointestinalInfectionsInhibitorinhibitorinhibit

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