2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. cFMS Receptor Inhibitor IV

cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM.

For research use only. We do not sell to patients.

cFMS Receptor Inhibitor IV Chemical Structure

cFMS Receptor Inhibitor IV Chemical Structure

CAS No. : 959626-45-0

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10 mg USD 115 In-stock
25 mg USD 235 In-stock
50 mg USD 375 In-stock
100 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

cFMS Receptor Inhibitor IV Related Antibodies

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Description

cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM[1].

IC50 & Target

IC50: 0.017 μM (cFMS)[1]
Molecular Weight

378.47

Formula

C22H26N4O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC=C(C#N)O1)NC2=CC(N3CCCCC3)=CC=C2N4CCCCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (82.57 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6422 mL 13.2111 mL 26.4222 mL
5 mM 0.5284 mL 2.6422 mL 5.2844 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6422 mL 13.2111 mL 26.4222 mL 66.0554 mL
5 mM 0.5284 mL 2.6422 mL 5.2844 mL 13.2111 mL
10 mM 0.2642 mL 1.3211 mL 2.6422 mL 6.6055 mL
15 mM 0.1761 mL 0.8807 mL 1.7615 mL 4.4037 mL
20 mM 0.1321 mL 0.6606 mL 1.3211 mL 3.3028 mL
25 mM 0.1057 mL 0.5284 mL 1.0569 mL 2.6422 mL
30 mM 0.0881 mL 0.4404 mL 0.8807 mL 2.2018 mL
40 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6514 mL
50 mM 0.0528 mL 0.2642 mL 0.5284 mL 1.3211 mL
60 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1009 mL
80 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
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cFMS Receptor Inhibitor IV Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cFMS Receptor Inhibitor IV959626-45-0c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RInhibitorinhibitorinhibit

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