2. Metabolic Enzyme/Protease
  3. Prolyl Endopeptidase (PREP)
  4. CGS 24592

CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure.

For research use only. We do not sell to patients.

CGS 24592 Chemical Structure

CGS 24592 Chemical Structure

CAS No. : 147923-04-4

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Description

CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure[1].

Molecular Weight

406.37

Formula

C19H23N2O6P
CAS No.
SMILES

OC(CCNC([C@@H](NCP(O)(O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CGS 24592 Related Classifications

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Keywords:

CGS 24592147923-04-4CGS24592CGS-24592Prolyl Endopeptidase (PREP)prolyl oligopeptidasePOPNEPANPhypertensioncongestive heart failureInhibitorinhibitorinhibit

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