2. Cell Cycle/DNA Damage Epigenetics Apoptosis
  3. HDAC Apoptosis
  4. Chlopynostat

Chlopynostat (Compound 6c) is a HDAC1 inhibitor with a IC50 value of 67 nM. Chlopynostat reverses STAT4/p66Shc defects by inhibiting HDAC1-induced < b>Apoptosis.

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Chlopynostat Chemical Structure

Chlopynostat Chemical Structure

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Chlopynostat Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

Chlopynostat (Compound 6c) is a HDAC1 inhibitor with a IC50 value of 67 nM. Chlopynostat reverses STAT4/p66Shc defects by inhibiting HDAC1-induced < b>Apoptosis[1].

IC50 & Target

HDAC1

67 nM (IC50)

Molecular Weight

404.85

Formula

C22H17ClN4O2
SMILES

O=C1N(CC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2)C=NC4=CC(Cl)=CC=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Chlopynostat Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ChlopynostatHDACApoptosisHistone deacetylasesHDAC1InhibitorChronic lymphocytic leukemiainhibitorinhibit

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HY-161464
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