1. Cell Cycle/DNA Damage Apoptosis Stem Cell/Wnt
  2. Casein Kinase Apoptosis
  3. CIGB-300 acetate

CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 acetate induces apoptosis in multiple tumor cell lines and can be used in cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CIGB-300 acetate Chemical Structure

CIGB-300 acetate Chemical Structure

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Description

CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 acetate induces apoptosis in multiple tumor cell lines and can be used in cancer research[1].

Molecular Weight

3060.60 (free base)

Formula

C127H215N53O30S3.xC2H4O2

Appearance

Solid

Sequence

Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-{βAla}-Cys-Trp-Met-Ser-Pro-Arg-His-Leu-Gly-Thr-Cys (Disulfide bridge: Cys15-Cys25)

Sequence Shortening

GRKKRRQRRRPPQ-{βAla}-CWMSPRHLGTC (Disulfide bridge: Cys15-Cys25)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CIGB-300 acetate
Cat. No.:
HY-P4056A
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