cis-Fmoc-Pro(4-N3)-OH

Name: cis-Fmoc-Pro(4-N3)-OH
Brand: MedChemExpress
SKU: HY-W142062
Rating: 4.5 (1 reviews)

Cat. No.: HY-W142062 Purity: 99.19%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

cis-Fmoc-Pro(4-N3)-OH is a proline derivative. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

cis-Fmoc-Pro(4-N3)-OH Chemical Structure

CAS No. : 263847-08-1

Size	Price	Stock	Quantity
50 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 128	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 243	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

cis-Fmoc-Pro(4-N3)-OH is a proline derivative^[1]. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

378.38

Formula

C₂₀H₁₈N₄O₄

CAS No.

263847-08-1

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 125 mg/mL (330.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6428 mL	13.2142 mL	26.4285 mL
5 mM	0.5286 mL	2.6428 mL	5.2857 mL
10 mM	0.2643 mL	1.3214 mL	2.6428 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.19%

Select Batch:

Data Sheet (278 KB) SDS (393 KB)

COA (257 KB) HNMR (296 KB) LCMS (270 KB)

Handling Instructions (2659 KB)

References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6428 mL	13.2142 mL	26.4285 mL	66.0711 mL
	5 mM	0.5286 mL	2.6428 mL	5.2857 mL	13.2142 mL
	10 mM	0.2643 mL	1.3214 mL	2.6428 mL	6.6071 mL
	15 mM	0.1762 mL	0.8809 mL	1.7619 mL	4.4047 mL
	20 mM	0.1321 mL	0.6607 mL	1.3214 mL	3.3036 mL
	25 mM	0.1057 mL	0.5286 mL	1.0571 mL	2.6428 mL
	30 mM	0.0881 mL	0.4405 mL	0.8809 mL	2.2024 mL
	40 mM	0.0661 mL	0.3304 mL	0.6607 mL	1.6518 mL
	50 mM	0.0529 mL	0.2643 mL	0.5286 mL	1.3214 mL
	60 mM	0.0440 mL	0.2202 mL	0.4405 mL	1.1012 mL
	80 mM	0.0330 mL	0.1652 mL	0.3304 mL	0.8259 mL
	100 mM	0.0264 mL	0.1321 mL	0.2643 mL	0.6607 mL