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  3. Fluorescent Dye
  4. cis-Ned19

cis-Ned19 is a chemical probe. cis-Ned19 blocks NAADP signaling and fluorescently labeled NAADP receptors in cell.

For research use only. We do not sell to patients.

cis-Ned19 Chemical Structure

cis-Ned19 Chemical Structure

CAS No. : 1137264-00-6

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Based on 1 publication(s) in Google Scholar

cis-Ned19 Related Antibodies

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Description

cis-Ned19 is a chemical probe. cis-Ned19 blocks NAADP signaling and fluorescently labeled NAADP receptors in cell[1].

Molecular Weight

514.59

Formula

C30H31FN4O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H]1CC2=C([C@H](C3=CC=C(OC)C(CN4CCN(C5=CC=CC=C5F)CC4)=C3)N1)NC6=C2C=CC=C6)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (194.33 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9433 mL 9.7165 mL 19.4329 mL
5 mM 0.3887 mL 1.9433 mL 3.8866 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9433 mL 9.7165 mL 19.4329 mL 48.5824 mL
5 mM 0.3887 mL 1.9433 mL 3.8866 mL 9.7165 mL
10 mM 0.1943 mL 0.9716 mL 1.9433 mL 4.8582 mL
15 mM 0.1296 mL 0.6478 mL 1.2955 mL 3.2388 mL
20 mM 0.0972 mL 0.4858 mL 0.9716 mL 2.4291 mL
25 mM 0.0777 mL 0.3887 mL 0.7773 mL 1.9433 mL
30 mM 0.0648 mL 0.3239 mL 0.6478 mL 1.6194 mL
40 mM 0.0486 mL 0.2429 mL 0.4858 mL 1.2146 mL
50 mM 0.0389 mL 0.1943 mL 0.3887 mL 0.9716 mL
60 mM 0.0324 mL 0.1619 mL 0.3239 mL 0.8097 mL
80 mM 0.0243 mL 0.1215 mL 0.2429 mL 0.6073 mL
100 mM 0.0194 mL 0.0972 mL 0.1943 mL 0.4858 mL
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cis-Ned19 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-Ned191137264-00-6Fluorescent DyeChemical ProbeNicotinic acid adenine dinucleotide phosphateNAADPNed-19Inhibitorinhibitorinhibit

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