1. Metabolic Enzyme/Protease Apoptosis
  2. Endogenous Metabolite Apoptosis
  3. Citicoline-d9 sodium

Citicoline-d9 sodium  (Synonyms: Cytidine diphosphate-choline-d9 (sodium); CDP-Choline-d9(sodium); Cytidine 5'-diphosphocholine-d9 (sodium))

Cat. No.: HY-B0739AS
COA Handling Instructions

Citicoline-d9 (sodium) is the deuterium labeled Citicoline sodium. Citicoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.

For research use only. We do not sell to patients.

Citicoline-d<sub>9</sub> sodium Chemical Structure

Citicoline-d9 sodium Chemical Structure

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1 mg USD 760 In-stock
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10 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Citicoline-d9 sodium:

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Citicoline-d9 (sodium) is the deuterium labeled Citicoline sodium. Citicoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

519.36

Formula

C14H16D9N4NaO11P2

Unlabeled CAS

33818-15-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@H]1[C@H](N(C=CC(N)=N2)C2=O)O[C@H](COP(OP(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([O-])=O)(O[Na])=O)[C@H]1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (192.54 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9254 mL 9.6272 mL 19.2545 mL
5 mM 0.3851 mL 1.9254 mL 3.8509 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.81%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.9254 mL 9.6272 mL 19.2545 mL 48.1362 mL
5 mM 0.3851 mL 1.9254 mL 3.8509 mL 9.6272 mL
10 mM 0.1925 mL 0.9627 mL 1.9254 mL 4.8136 mL
15 mM 0.1284 mL 0.6418 mL 1.2836 mL 3.2091 mL
20 mM 0.0963 mL 0.4814 mL 0.9627 mL 2.4068 mL
25 mM 0.0770 mL 0.3851 mL 0.7702 mL 1.9254 mL
30 mM 0.0642 mL 0.3209 mL 0.6418 mL 1.6045 mL
40 mM 0.0481 mL 0.2407 mL 0.4814 mL 1.2034 mL
50 mM 0.0385 mL 0.1925 mL 0.3851 mL 0.9627 mL
60 mM 0.0321 mL 0.1605 mL 0.3209 mL 0.8023 mL
80 mM 0.0241 mL 0.1203 mL 0.2407 mL 0.6017 mL
100 mM 0.0193 mL 0.0963 mL 0.1925 mL 0.4814 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Citicoline-d9 sodium
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HY-B0739AS
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