CLK1/2-IN-2

Cat. No.: HY-113670: FAQs
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CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC₅₀ values of 1.1 nM and 2.4 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities^{[1]^.}

For research use only. We do not sell to patients.

CLK1/2-IN-2 Chemical Structure

CAS No. : 1005776-20-4

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Description	CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC₅₀ values of 1.1 nM and 2.4 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities^{[1]^.}
Molecular Weight	360.41
Formula	C₂₀H₂₀N₆O
CAS No.	1005776-20-4
SMILES	O=C(NC1=CN2C(C=CC(C3=CNN=C3)=C2)=N1)C4=CC=C(N=C4)C(C)(C)C
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One [Content Brief]

CLK1/2-IN-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CLK1/2-IN-21005776-20-4CDKCyclin dependent kinaseMDA-MB-468A549COLO205HCT-116NCI-H23SW620COLO320DMbreast cancercolorectal cancernon-small cell lung cancerInhibitorinhibitorinhibit

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CLK1/2-IN-2

CLK1/2-IN-2 Related Antibodies

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