2. Cell Cycle/DNA Damage
  3. Poly(ADP-ribose) Glycohydrolase (PARG)
  4. COH34 analog 1

COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

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COH34 analog 1 Chemical Structure

COH34 analog 1 Chemical Structure

CAS No. : 314248-24-3

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Based on 1 publication(s) in Google Scholar

COH34 analog 1 Related Antibodies

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Description

COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1].

Molecular Weight

325.38

Formula

C18H15NO3S
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=S(C1=CC=C(C)C=C1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (307.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0733 mL 15.3666 mL 30.7333 mL
5 mM 0.6147 mL 3.0733 mL 6.1467 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0733 mL 15.3666 mL 30.7333 mL 76.8332 mL
5 mM 0.6147 mL 3.0733 mL 6.1467 mL 15.3666 mL
10 mM 0.3073 mL 1.5367 mL 3.0733 mL 7.6833 mL
15 mM 0.2049 mL 1.0244 mL 2.0489 mL 5.1222 mL
20 mM 0.1537 mL 0.7683 mL 1.5367 mL 3.8417 mL
25 mM 0.1229 mL 0.6147 mL 1.2293 mL 3.0733 mL
30 mM 0.1024 mL 0.5122 mL 1.0244 mL 2.5611 mL
40 mM 0.0768 mL 0.3842 mL 0.7683 mL 1.9208 mL
50 mM 0.0615 mL 0.3073 mL 0.6147 mL 1.5367 mL
60 mM 0.0512 mL 0.2561 mL 0.5122 mL 1.2806 mL
80 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.9604 mL
100 mM 0.0307 mL 0.1537 mL 0.3073 mL 0.7683 mL
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COH34 analog 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COH34 analog 1314248-24-3Poly(ADP-ribose) Glycohydrolase (PARG)Inhibitorinhibitorinhibit

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