2. Cell Cycle/DNA Damage Cytoskeleton Immunology/Inflammation Autophagy Apoptosis
  3. Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis
  4. Colchicine (Standard)

Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research.

For research use only. We do not sell to patients.

Colchicine (Standard) Chemical Structure

Colchicine (Standard) Chemical Structure

CAS No. : 64-86-8

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Colchicine (Standard) Related Classifications

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Keywords:

Colchicine (Standard)64-86-8Microtubule/TubulinNOD-like Receptor (NLR)AutophagyApoptosisOrallyalkaloidtubulinmicrotubuleα3 glycine receptorsGlyRsnon-steroidal anti-inflammatory drugNSAIDintestinal injuryimmunosuppressiveanti-fibrosisgouty arthritisAlzheimer’s diseaseADInhibitorinhibitorinhibit

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