5637
|
EC50 |
0.053 μM
Compound: Colchicine
|
Antiproliferative activity against human 5637 cells after 96 hrs by MTT assay
Antiproliferative activity against human 5637 cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
786-0
|
IC50 |
0.022 μM
Compound: Colchicine
|
Cytotoxicity against human 786-O cells after 72 hrs by MTT assay
Cytotoxicity against human 786-O cells after 72 hrs by MTT assay
|
[PMID: 30106297]
|
786-0
|
IC50 |
26.8 nM
Compound: Colchicine
|
Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
A10
|
EC50 |
|
Inhibition of microtubule depolymerization in rat A10 cells after 18 hrs by immunofluorescence assay
Inhibition of microtubule depolymerization in rat A10 cells after 18 hrs by immunofluorescence assay
|
[PMID: 23457660]
|
A10
|
EC50 |
|
Induction of interphase microtubule depolymerization in rat A10 cells after 18 to 24 hrs by DAPI staining-based indirect immunofluorescence assay
Induction of interphase microtubule depolymerization in rat A10 cells after 18 to 24 hrs by DAPI staining-based indirect immunofluorescence assay
|
[PMID: 23961916]
|
A2780
|
IC50 |
> 20 μM
Compound: Colchicine
|
Cytotoxicity against taxol-resistant human A2780 cells by MTT assay
Cytotoxicity against taxol-resistant human A2780 cells by MTT assay
|
[PMID: 23425970]
|
A2780
|
IC50 |
0.008 μM
Compound: Colchicine
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A2780
|
IC50 |
0.015 μM
Compound: colchicine
|
Cytotoxicity against human A2780 cells after 24 hrs by MTT assay
Cytotoxicity against human A2780 cells after 24 hrs by MTT assay
|
[PMID: 25426924]
|
A2780
|
IC50 |
0.02 μM
Compound: Colchicine
|
Cytotoxicity against human A2780S cells by MTT assay
Cytotoxicity against human A2780S cells by MTT assay
|
[PMID: 23425970]
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells after 48 hrs by SRB method
Antiproliferative activity against human A2780 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
A2780
|
IC50 |
|
Antiproliferative activity against taxol-resistant human A2780 cells after 48 hrs by SRB method
Antiproliferative activity against taxol-resistant human A2780 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780 cells after 48 hrs by MTT assay
Cytotoxicity against human A2780 cells after 48 hrs by MTT assay
|
[PMID: 30448418]
|
A2780
|
IC50 |
14 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
A2780
|
IC50 |
4 nM
Compound: colchicine
|
Antiproliferative activity against human A2780S cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human A2780S cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
A2780
|
EC50 |
8.7 nM
Compound: Colchicine
|
Antiproliferative activity against D4-9-31 resistance human A2780 cells incubated for 72 hrs by ATPlite reagent based assay
Antiproliferative activity against D4-9-31 resistance human A2780 cells incubated for 72 hrs by ATPlite reagent based assay
|
[PMID: 31047749]
|
A2780
|
EC50 |
9.2 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780 cells incubated for 72 hrs by ATPlite reagent based assay
Antiproliferative activity against human A2780 cells incubated for 72 hrs by ATPlite reagent based assay
|
[PMID: 31047749]
|
A2780 ADR
|
IC50 |
0.306 μM
Compound: colchicine
|
Cytotoxicity against human A2780AD cells after 24 hrs by MTT assay
Cytotoxicity against human A2780AD cells after 24 hrs by MTT assay
|
[PMID: 25426924]
|
A2780 ADR
|
IC50 |
16.8 nM
Compound: colchicine
|
Cytotoxicity against human A2780AD cells expressing p-gp after 96 hrs by MTT assay
Cytotoxicity against human A2780AD cells expressing p-gp after 96 hrs by MTT assay
|
[PMID: 23176628]
|
A2780/Taxol
|
IC50 |
35632.33 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780T cells after 48 to 72 hrs by MTT assay
Antiproliferative activity against human A2780T cells after 48 to 72 hrs by MTT assay
|
[PMID: 29754076]
|
A2780/Taxol
|
IC50 |
783.8 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780T cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A2780T cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
A2780/Taxol
|
IC50 |
|
Cytotoxicity against beta-tubulin 3 overexpressing human A2780T cells assessed as reduction in cell growth after 24 hrs by MTT assay
Cytotoxicity against beta-tubulin 3 overexpressing human A2780T cells assessed as reduction in cell growth after 24 hrs by MTT assay
|
[PMID: 27213819]
|
A2780S
|
IC50 |
12.3 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780S cells after 48 hrs by MTT assay
Antiproliferative activity against human A2780S cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
A2780S
|
IC50 |
16.7 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780S cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A2780S cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
A2780S
|
IC50 |
21.86 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780S cells after 48 to 72 hrs by MTT assay
Antiproliferative activity against human A2780S cells after 48 to 72 hrs by MTT assay
|
[PMID: 29754076]
|
A2780S
|
IC50 |
|
Antiproliferative activity against human A2780S cells after 24 hrs by MTT assay
Antiproliferative activity against human A2780S cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
A2780S
|
IC50 |
31 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780S cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Antiproliferative activity against human A2780S cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35084853]
|
A2780S
|
IC50 |
34.1 nM
Compound: Colchicine
|
Antiproliferative activity against human A2780S cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A2780S cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
A-375
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells assessed as cell growth inhibition after 96 hrs by MTT assay
Antiproliferative activity against human A375 cells assessed as cell growth inhibition after 96 hrs by MTT assay
|
[PMID: 27094151]
|
A-375
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells after 48 hrs by SRB assay
Antiproliferative activity against human A375 cells after 48 hrs by SRB assay
|
[PMID: 22608389]
|
A-375
|
IC50 |
0.02 μM
Compound: colchicine
|
Cytotoxicity against human A375 cells after 48 hrs by SRB assay
Cytotoxicity against human A375 cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
A-375
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A375 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
A-375
|
IC50 |
10.9 nM
Compound: Colchicine
|
Antiproliferative activity against human A-375 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human A-375 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
A-375
|
IC50 |
12 nM
Compound: colchicine
|
Antiproliferative activity against human A375 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human A375 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
A-375
|
IC50 |
14.1 nM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
|
[PMID: 31251599]
|
A-375
|
IC50 |
16.8 nM
Compound: Colchicine
|
Cytotoxicity against human A-375 cells measured after 72 hrs by western blot
Cytotoxicity against human A-375 cells measured after 72 hrs by western blot
|
[PMID: 34378386]
|
A-375
|
IC50 |
20 nM
Compound: Colchicine
|
Cytotoxicity against human A375 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human A375 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
A-375
|
IC50 |
20.6 nM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells after 48 hrs by SRB assay
Antiproliferative activity against human A375 cells after 48 hrs by SRB assay
|
[PMID: 22783954]
|
A-375
|
IC50 |
6.4 nM
Compound: Colchicine
|
Cytotoxicity against human A375 cells after 72 hrs by MTS assay
Cytotoxicity against human A375 cells after 72 hrs by MTS assay
|
[PMID: 29406710]
|
A-375
|
IC50 |
9.7 nM
Compound: Colchicine
|
Antiproliferative activity against human A375 cells after 72 hrs by MTS assay
Antiproliferative activity against human A375 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
A375/TxR
|
IC50 |
23.6 nM
Compound: Colchicine
|
Antiproliferative activity against human A375/TxR cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human A375/TxR cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
A375/TxR
|
IC50 |
29.6 nM
Compound: Colchicine
|
Cytotoxicity against paclitaxel resistant human A-375/TxR cells measured after 72 hrs by western blot
Cytotoxicity against paclitaxel resistant human A-375/TxR cells measured after 72 hrs by western blot
|
[PMID: 34378386]
|
A-427
|
EC50 |
0.045 μM
Compound: Colchicine
|
Antiproliferative activity against human A427 cells after 96 hrs by MTT assay
Antiproliferative activity against human A427 cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
A-431
|
EC50 |
0.0028 μM
Compound: Colchicine
|
Cell cycle arrest in A431 cells by accumulation at G2/M phase cell
Cell cycle arrest in A431 cells by accumulation at G2/M phase cell
|
[PMID: 16198562]
|
A-431
|
IC50 |
0.008 μM
Compound: Colchicine
|
Cytotoxicity against human A431 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human A431 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25091926]
|
A-431
|
IC50 |
0.019 μM
Compound: Colchicine
|
Cytotoxicity against human A431 cells after 72 hrs by MTT assay
Cytotoxicity against human A431 cells after 72 hrs by MTT assay
|
[PMID: 23602523]
|
A-431
|
IC50 |
53.2 nM
Compound: Colchicine
|
Antiproliferative activity against human A431 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human A431 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
A549
|
IC50 |
< 1 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 20833451]
|
A549
|
ED50 |
0.002 μg/mL
Compound: colchicine
|
Cytotoxicity against human lung carcinoma cells (A-549) using SRB assay.
Cytotoxicity against human lung carcinoma cells (A-549) using SRB assay.
|
[PMID: 9544215]
|
A549
|
IC50 |
0.013 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells harboring control siRNA after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells harboring control siRNA after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A549
|
IC50 |
0.015 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells harboring katanin siRNA after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells harboring katanin siRNA after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A549
|
IC50 |
0.017 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
A549
|
ED50 |
|
Cytotoxicity against human A549 cells after 2 days
Cytotoxicity against human A549 cells after 2 days
|
[PMID: 20542428]
|
A549
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells by SRB assay
Antiproliferative activity against human A549 cells by SRB assay
|
[PMID: 28988750]
|
A549
|
IC50 |
0.023 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 30093295]
|
A549
|
IC50 |
0.023 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 23602523]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
A549
|
IC50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
A549
|
GI50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
|
[PMID: 25827522]
|
A549
|
IC50 |
0.031 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
A549
|
IC50 |
0.043 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30106297]
|
A549
|
IC50 |
0.045 μM
Compound: 1, colchicine
|
Antiproliferative activity against human A549 cells after 72 hrs
Antiproliferative activity against human A549 cells after 72 hrs
|
[PMID: 18503262]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by SRB method
Antiproliferative activity against human A549 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
A549
|
IC50 |
0.053 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells assessed as reduction in cell growth by CCK8 assay
Cytotoxicity against human A549 cells assessed as reduction in cell growth by CCK8 assay
|
[PMID: 33753264]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by sulforhodamine B assay
|
[PMID: 32432867]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
|
[PMID: 24900316]
|
A549
|
IC50 |
|
Antiproliferative activity against cis-platinum-resistant human A549 cells after 48 hrs by SRB method
Antiproliferative activity against cis-platinum-resistant human A549 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
A549
|
IC50 |
0.095 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34571171]
|
A549
|
IC50 |
0.105 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
A549
|
IC50 |
0.107 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
|
[PMID: 32650183]
|
A549
|
IC50 |
0.108 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
A549
|
IC50 |
0.111 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
A549
|
IC50 |
0.12 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
A549
|
IC50 |
0.12 μM
Compound: Colchicine
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 25499929]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
A549
|
IC50 |
0.184 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 36455508]
|
A549
|
IC50 |
0.19 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
|
[PMID: 34022412]
|
A549
|
IC50 |
0.19 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 33965530]
|
A549
|
IC50 |
0.2 μg/mL
Compound: Colchicine
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22578453]
|
A549
|
IC50 |
0.22 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
A549
|
IC50 |
0.47 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 24 hrs by MTT assay
|
10.1039/C6MD00255B
|
A549
|
IC50 |
0.47 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
|
[PMID: 35367708]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
A549
|
IC50 |
0.58 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
A549
|
IC50 |
0.74 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22503741]
|
A549
|
IC50 |
0.75 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22261027]
|
A549
|
IC50 |
0.75 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
|
[PMID: 36970147]
|
A549
|
IC50 |
1.09 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37122544]
|
A549
|
IC50 |
1.17 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
A549
|
IC50 |
10.78 ng/mL
Compound: colchicine
|
Cytotoxicity against human A549 cells after 24 hrs by YO-PRO-1 assay
Cytotoxicity against human A549 cells after 24 hrs by YO-PRO-1 assay
|
[PMID: 19138858]
|
A549
|
IC50 |
10.78 ng/mL
Compound: colchicine
|
Cytotoxicity against human A549 cells after 24 hrs by propidium iodide assay
Cytotoxicity against human A549 cells after 24 hrs by propidium iodide assay
|
[PMID: 19138858]
|
A549
|
IC50 |
12.2 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 2 days by MTT assay
Antiproliferative activity against human A549 cells after 2 days by MTT assay
|
[PMID: 29550732]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by SRB assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by SRB assay
|
[PMID: 33465696]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
|
[PMID: 31653441]
|
A549
|
IC50 |
14 nM
Compound: Colchicine
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 27915168]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
|
[PMID: 34592435]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by CCK-8 assay
Cytotoxicity against human A549 cells after 72 hrs by CCK-8 assay
|
[PMID: 23360369]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
A549
|
IC50 |
21 nM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
|
[PMID: 31655432]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
Cytotoxicity against human A549 cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 26985296]
|
A549
|
EC50 |
27 nM
Compound: Colchicine
|
Cytotoxicity against human A549 cells after 24 hrs by MTT assay
Cytotoxicity against human A549 cells after 24 hrs by MTT assay
|
[PMID: 21873068]
|
A549
|
IC50 |
32.7 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
A549
|
IC50 |
32.76 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 to 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 to 72 hrs by MTT assay
|
[PMID: 29754076]
|
A549
|
IC50 |
37 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 33234343]
|
A549
|
IC50 |
37 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
A549
|
GI50 |
4.4 μM
Compound: Colchicine
|
Growth inhibition of human A549 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human A549 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
A549
|
IC50 |
4.64 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
A549
|
IC50 |
|
Cytotoxicity against 2D culture of human A549 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human A549 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
|
[PMID: 33611191]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 35694693]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay
Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay
|
[PMID: 22727370]
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 96 hrs
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 96 hrs
|
10.1039/C3MD00287J
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 96 hrs by microplate reader analysis
Cytotoxicity against human A549 cells after 96 hrs by microplate reader analysis
|
10.1039/C2MD20250F
|
A549
|
IC50 |
|
Growth inhibition of human A549 cells incubated for 48 hrs by MTT assay
Growth inhibition of human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 27172319]
|
A549
|
IC50 |
62.7 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
|
[PMID: 34116158]
|
A549
|
IC50 |
77.6 nM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
A549
|
IC50 |
9.7 μM
Compound: Colchicine
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
A549/TR
|
IC50 |
167.34 nM
Compound: Colchicine
|
Antiproliferative activity against human A549/TR cells after 48 to 72 hrs by MTT assay
Antiproliferative activity against human A549/TR cells after 48 to 72 hrs by MTT assay
|
[PMID: 29754076]
|
A549/TR
|
IC50 |
202.9 nM
Compound: Colchicine
|
Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
ACHN
|
IC50 |
39.8 nM
Compound: colchicine
|
Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
AGS
|
GI50 |
0.04 μM
Compound: Colchicine
|
Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
|
[PMID: 28763647]
|
AGS
|
IC50 |
9 nM
Compound: colchicine
|
Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
B16
|
IC50 |
0.031 μM
Compound: Colchicine
|
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT test
Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT test
|
[PMID: 18583138]
|
B16-F0
|
IC50 |
0.087 μM
Compound: Colchicine
|
Antiproliferative activity against mouse B16-F0 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
Antiproliferative activity against mouse B16-F0 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
|
[PMID: 32650183]
|
B16-F1
|
IC50 |
0.029 μM
Compound: colchicine
|
Cytotoxicity against mouse B16-F1 cells after 48 hrs by SRB assay
Cytotoxicity against mouse B16-F1 cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
B16-F1
|
IC50 |
29 nM
Compound: Colchicine
|
Cytotoxicity against mouse B16-F1 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against mouse B16-F1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
B16-F10
|
IC50 |
0.003 μM
Compound: Colchicine
|
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
B16-F10
|
IC50 |
0.029 μM
Compound: 1, colchicine
|
Antiproliferative activity against mouse B16F10 cells after 72 hrs
Antiproliferative activity against mouse B16F10 cells after 72 hrs
|
[PMID: 18503262]
|
B16-F10
|
IC50 |
0.083 μM
Compound: Colchicine
|
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against mouse B16-F10 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
B16-F10
|
IC50 |
0.48 μM
Compound: Colchicine
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
B16-F10
|
IC50 |
0.5 μg/mL
Compound: Colchicine
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT based ELISA assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT based ELISA assay
|
[PMID: 21783370]
|
B16-F10
|
IC50 |
0.8 μg/mL
Compound: Colchicine
|
Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay
Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay
|
[PMID: 22578453]
|
B16-F10
|
IC50 |
32 nM
Compound: Colchicine
|
Antiproliferative activity against mouse B16F10 cells after 72 hrs by MTS assay
Antiproliferative activity against mouse B16F10 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
B16-F10
|
IC50 |
|
Cytotoxicity against mouse B16-F10 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
|
[PMID: 36970147]
|
B16-F10
|
IC50 |
44.25 nM
Compound: Colchicine
|
Antiproliferative activity against mouse B16F10 cells after 72 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 72 hrs by MTT assay
|
[PMID: 30197030]
|
B16-F10
|
IC50 |
9.6 μM
Compound: Colchicine
|
Induction of cell cycle arrest in mouse B16-F10 cells assessed as accumulation of cells at G2/M phase incubated for 48 hrs by RNase/PI staining based flow cytometry analysis
Induction of cell cycle arrest in mouse B16-F10 cells assessed as accumulation of cells at G2/M phase incubated for 48 hrs by RNase/PI staining based flow cytometry analysis
|
[PMID: 35043615]
|
BALB/3T3
|
IC50 |
|
Cytotoxicity against mouse BALB/3T3 cells incubated for 72 hrs by sulforhodamine B assay
Cytotoxicity against mouse BALB/3T3 cells incubated for 72 hrs by sulforhodamine B assay
|
[PMID: 32432867]
|
BALB/3T3
|
IC50 |
|
Antiproliferative activity against mouse BALB/3T3 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
Antiproliferative activity against mouse BALB/3T3 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
|
[PMID: 34116158]
|
BALB/3T3
|
IC50 |
|
Antiproliferative activity against mouse BALB/3T3 cells incubated for 72 hrs by SRB assay
Antiproliferative activity against mouse BALB/3T3 cells incubated for 72 hrs by SRB assay
|
[PMID: 33465696]
|
BALB/3T3
|
IC50 |
|
Antiproliferative activity against mouse BALB/3T3 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
Antiproliferative activity against mouse BALB/3T3 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
|
[PMID: 31653441]
|
BALB/3T3
|
IC50 |
|
Cytotoxicity against mouse BALB/3T3 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
Cytotoxicity against mouse BALB/3T3 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
|
[PMID: 33611191]
|
BALB/3T3
|
IC50 |
|
Cytotoxicity against mouse BALB/3T3 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Cytotoxicity against mouse BALB/3T3 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
|
[PMID: 34592435]
|
BEAS-2B
|
IC50 |
0.016 μM
Compound: Colchicine
|
Cytotoxicity against human BEAS-2B cells assessed as reduction in cell growth by CCK8 assay
Cytotoxicity against human BEAS-2B cells assessed as reduction in cell growth by CCK8 assay
|
[PMID: 33753264]
|
Bel-7402
|
IC50 |
0.04 μM
Compound: Colchicine
|
Antiproliferative activity against human Bel7402 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human Bel7402 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
Bel-7402
|
IC50 |
0.3 μg/mL
Compound: colchicine
|
Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
|
[PMID: 15620246]
|
Bel-7402
|
IC50 |
0.4 μg/mL
Compound: Colchicine
|
Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
|
[PMID: 15165134]
|
Bel-7402
|
IC50 |
1.31 μM
Compound: Colchicine
|
Cytotoxicity against human Bel7402 cells by MTT assay
Cytotoxicity against human Bel7402 cells by MTT assay
|
[PMID: 23425970]
|
BGC-823
|
IC50 |
0.016 μM
Compound: Colchicine
|
Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
BGC-823
|
IC50 |
0.6 μg/mL
Compound: colchicine
|
Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
|
[PMID: 15620246]
|
BJAB
|
IC50 |
|
Antiproliferative activity against human BJAB cells after 24 hrs by CASY cell counting method
Antiproliferative activity against human BJAB cells after 24 hrs by CASY cell counting method
|
10.1039/C5MD00320B
|
BT-474
|
IC50 |
|
Cytotoxicity against human BT-474 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
Cytotoxicity against human BT-474 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
|
[PMID: 36970147]
|
BT-474
|
IC50 |
|
Cytotoxicity against human BT474 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human BT474 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
BT-549
|
IC50 |
0.023 μM
Compound: colchicine
|
Antiproliferative activity against human BT549 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human BT549 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
Burkitts lymphoma cell
|
IC50 |
|
Growth inhibition on human burkitt lymphoma cells after 36 h
Growth inhibition on human burkitt lymphoma cells after 36 h
|
[PMID: 8496935]
|
BXPC-3
|
IC50 |
|
Cell cycle arrest in human BxPC3 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human BxPC3 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
BXPC-3
|
IC50 |
|
Cytotoxicity against human BxPC-3 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human BxPC-3 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
BXPC-3
|
IC50 |
|
Cytotoxicity against human BxPC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human BxPC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33479669]
|
BXPC-3
|
IC50 |
|
Cytotoxicity against 2D culture of human BxPC3 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human BxPC3 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
C6
|
EC50 |
1 x 10 -1 μM
Compound: Colchicine
|
Inhibition of tubulin polymerization in rat C6 cells after 4 hrs
Inhibition of tubulin polymerization in rat C6 cells after 4 hrs
|
[PMID: 8988604]
|
Caco-2
|
GI50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human Caco2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human Caco2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
|
[PMID: 30288225]
|
CAL-27
|
IC50 |
37.5 nM
Compound: Colchicine
|
Antiproliferative activity against human CAL-27 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human CAL-27 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
CCRF-CEM
|
IC50 |
0.013 μM
Compound: 1, colch
|
Antiproliferative activity against human CEM cells after 48 to 96 hrs by coulter counter analysis
Antiproliferative activity against human CEM cells after 48 to 96 hrs by coulter counter analysis
|
[PMID: 24773591]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells measured after 96 hrs by Coulter counter method
Antiproliferative activity against human CEM cells measured after 96 hrs by Coulter counter method
|
[PMID: 30921759]
|
CCRF-CEM
|
IC50 |
0.013 μM
Compound: Colchicine
|
Antiproliferative activity against human CEM cells after 96 hrs by coulter counting method
Antiproliferative activity against human CEM cells after 96 hrs by coulter counting method
|
[PMID: 29471122]
|
CCRF-CEM
|
IC50 |
0.0172 μM
Compound: Colchicine
|
Cytotoxicity against human CEM cells after 72 hrs by MTT assay
Cytotoxicity against human CEM cells after 72 hrs by MTT assay
|
[PMID: 21536450]
|
CCRF-CEM
|
EC50 |
0.021 μM
Compound: Colchicine
|
Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay
Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
CCRF-CEM
|
IC50 |
0.031 μM
Compound: Colchicine
|
Antiproliferative activity against human CEM cells assessed as inhibition of cell proliferation after 96 hrs by Coulter counter based cell counting method
Antiproliferative activity against human CEM cells assessed as inhibition of cell proliferation after 96 hrs by Coulter counter based cell counting method
|
[PMID: 25282265]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM after 48 hrs by SRB assay
Antiproliferative activity against human CEM after 48 hrs by SRB assay
|
[PMID: 21920638]
|
CCRF-CEM
|
IC50 |
|
Antiproliferative activity against human CEM cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human CEM cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
CEM-VLB
|
IC50 |
|
Antiproliferative activity against human multidrug-resistant CEM/VLB cells after 48 hrs by SRB assay
Antiproliferative activity against human multidrug-resistant CEM/VLB cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
CEM-VLB
|
IC50 |
|
Antiproliferative activity against multidrug-resistant human CEM/VLB cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against multidrug-resistant human CEM/VLB cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
CHL-1
|
IC50 |
3.6 nM
Compound: Colchicine
|
Antiproliferative activity against human CHL-1 cells after 72 hrs by MTS assay
Antiproliferative activity against human CHL-1 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
CHO
|
IC50 |
|
Antiproliferative activity against human CHO after 48 hrs by SRB assay
Antiproliferative activity against human CHO after 48 hrs by SRB assay
|
[PMID: 21920638]
|
CHO
|
IC50 |
|
Antiproliferative activity against CHO cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against CHO cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
CHO-TAX 5-6
|
IC50 |
|
Antiproliferative activity against paclitaxel-resistant CHO-TAX 5-6 cells after 48 hrs by SRB assay
Antiproliferative activity against paclitaxel-resistant CHO-TAX 5-6 cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
CHO-TAX 5-6
|
IC50 |
|
Antiproliferative activity against paclitaxel-resistant CHO-TAX 5-6 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against paclitaxel-resistant CHO-TAX 5-6 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
CHO-VV 3-2
|
IC50 |
|
Antiproliferative activity against colchicine and vinblastine-resistant CHO-VV 3-2 cells after 48 hrs by SRB assay
Antiproliferative activity against colchicine and vinblastine-resistant CHO-VV 3-2 cells after 48 hrs by SRB assay
|
[PMID: 21920638]
|
CHO-VV 3-2
|
IC50 |
|
Antiproliferative activity against paclitaxel-resistant CHO-VV 3-2 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against paclitaxel-resistant CHO-VV 3-2 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
CNE-2
|
IC50 |
|
Antiproliferative activity against human CNE2 cells after 48 hrs by SRB method
Antiproliferative activity against human CNE2 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
COLO 205
|
IC50 |
0.003 μM
Compound: Colchicine
|
Cytotoxicity against human COLO205 cells assessed as growth inhibition by MTT assay
Cytotoxicity against human COLO205 cells assessed as growth inhibition by MTT assay
|
[PMID: 25091926]
|
COLO 205
|
IC50 |
0.021 μM
Compound: colchicine
|
Antiproliferative activity against human COLO205 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human COLO205 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
COLO 205
|
IC50 |
0.032 μM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 31655432]
|
COLO357
|
IC50 |
|
Antiproliferative activity against human COLO357 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human COLO357 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
COLO357
|
IC50 |
|
Cytotoxic activity in human Colo-357 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxic activity in human Colo-357 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 29028531]
|
COLO357
|
IC50 |
|
Cytotoxicity against human COLO-357 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human COLO-357 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33479669]
|
COLO357
|
IC50 |
|
Cytotoxicity against 2D culture of human Colo-357 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human Colo-357 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
DAN-G
|
EC50 |
0.059 μM
Compound: Colchicine
|
Antiproliferative activity against human DAN-G cells after 96 hrs by MTT assay
Antiproliferative activity against human DAN-G cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
DLD-1
|
IC50 |
0.089 μM
Compound: colchicine
|
Antiproliferative activity against human DLD1 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human DLD1 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
DLD-1
|
EC50 |
0.18 μM
Compound: Colchicine
|
Induction of apoptosis in human DLD1 cells assessed as caspase activation after 48 hrs
Induction of apoptosis in human DLD1 cells assessed as caspase activation after 48 hrs
|
[PMID: 19500976]
|
DLD-1
|
EC50 |
0.19 μM
Compound: colchicine
|
Induction of apoptosis in human DLD1 cells assessed as caspase activation after 24 hrs
Induction of apoptosis in human DLD1 cells assessed as caspase activation after 24 hrs
|
[PMID: 15566300]
|
DLD-1
|
IC50 |
11 nM
Compound: colchicine
|
Antiproliferative activity against human DLD1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human DLD1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
DLD-1
|
IC50 |
15.6 nM
Compound: colchicine
|
Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay
Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay
|
[PMID: 23176628]
|
DLD-1
|
IC50 |
|
Cytotoxicity against human DLD1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human DLD1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
DU-145
|
ED50 |
|
Cytotoxicity against human DU145 cells after 2 days
Cytotoxicity against human DU145 cells after 2 days
|
[PMID: 20542428]
|
DU-145
|
IC50 |
0.003 μM
Compound: Colchicine
|
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
DU-145
|
IC50 |
0.01 μM
Compound: colchicine
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
DU-145
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human DU145 cells after 96 hrs by sulforhodamine B assay
Antiproliferative activity against human DU145 cells after 96 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
DU-145
|
EC50 |
0.018 μM
Compound: Colchicine
|
Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
DU-145
|
IC50 |
0.3 μM
Compound: Colchicine
|
Cytotoxicity against human DU145 cells by MTT assay
Cytotoxicity against human DU145 cells by MTT assay
|
[PMID: 23425970]
|
DU-145
|
IC50 |
0.69 μM
Compound: Colchicine
|
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
|
[PMID: 25499929]
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 after 48 hrs by SRB assay
Antiproliferative activity against human DU145 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
DU-145
|
IC50 |
10 nM
Compound: Colchicine
|
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
DU-145
|
IC50 |
11.2 nM
Compound: Colchicine
|
Antiproliferative activity against human DU145 cells after 48 hrs by SRB assay
Antiproliferative activity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 22783954]
|
DU-145
|
IC50 |
17.3 nM
Compound: Colchicine
|
Antiproliferative activity against human DU145 cells measured after 72 hrs by MTS assay
Antiproliferative activity against human DU145 cells measured after 72 hrs by MTS assay
|
[PMID: 31860298]
|
DU-145
|
IC50 |
25.7 nM
Compound: Colchicine
|
Cytotoxicity against human DU145 cells after 72 hrs by MTS assay
Cytotoxicity against human DU145 cells after 72 hrs by MTS assay
|
[PMID: 29406710]
|
DU-145
|
IC50 |
3.45 nM
Compound: Colchicine
|
Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay
|
[PMID: 30197030]
|
EA.hy 926
|
IC50 |
|
Cytotoxicity against 2D culture of human EAhy926 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human EAhy926 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
ECa-109 cell line
|
IC50 |
1.24 μM
Compound: Colchicine
|
Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
|
[PMID: 30075402]
|
Epithelial cell
|
IC50 |
9.26 μM
Compound: Colchicine
|
Antiproliferative activity against human mammary epithelial cells after 48 hrs by MTT assay
Antiproliferative activity against human mammary epithelial cells after 48 hrs by MTT assay
|
[PMID: 27608432]
|
FaDu
|
IC50 |
22.8 nM
Compound: Colchicine
|
Antiproliferative activity against human FaDu cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human FaDu cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
H9
|
IC50 |
|
Antiviral activity against HIV1 HTLV-3B in human H9 cells after 3 days by p24 antigen capture assay
Antiviral activity against HIV1 HTLV-3B in human H9 cells after 3 days by p24 antigen capture assay
|
[PMID: 1919593]
|
HaCaT
|
IC50 |
|
Cytotoxicity against human HaCat cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HaCat cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
HaCaT
|
IC50 |
12 nM
Compound: Colchicine
|
Antiproliferative activity against human HaCaT cells assessed as cell viability by MTT assay
Antiproliferative activity against human HaCaT cells assessed as cell viability by MTT assay
|
[PMID: 23063401]
|
HaCaT
|
IC50 |
|
Cytotoxicity against human HaCaT cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HaCaT cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33479669]
|
HaCaT
|
IC50 |
|
Cytotoxicity against 2D culture of human HaCaT cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human HaCaT cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
HCT-116
|
IC50 |
0.003 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
HCT-116
|
IC50 |
0.005 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
HCT-116
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells by SRB assay
Antiproliferative activity against human HCT116 cells by SRB assay
|
[PMID: 28988750]
|
HCT-116
|
IC50 |
0.011 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 36455508]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
|
[PMID: 24900316]
|
HCT-116
|
EC50 |
0.015 μM
Compound: colchicine
|
Induction of apoptosis in human HCT116 cells assessed as caspase activation after 24 hrs by HTS assay
Induction of apoptosis in human HCT116 cells assessed as caspase activation after 24 hrs by HTS assay
|
[PMID: 18197614]
|
HCT-116
|
EC50 |
0.015 μM
Compound: colchicine
|
Induction of apoptosis in human HCT116 cells assessed as caspase 3 activation after 24 hrs
Induction of apoptosis in human HCT116 cells assessed as caspase 3 activation after 24 hrs
|
[PMID: 18651728]
|
HCT-116
|
IC50 |
0.037 μM
Compound: Colchicine
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 23602523]
|
HCT-116
|
IC50 |
0.039 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 30093295]
|
HCT-116
|
IC50 |
0.04 μM
Compound: Colchicine
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
HCT-116
|
IC50 |
0.04 μM
Compound: Colchicine
|
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by SRB assay
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by SRB assay
|
[PMID: 30883116]
|
HCT-116
|
IC50 |
0.04 μM
Compound: 1, colchicine
|
Antiproliferative activity against human HCT116 cells after 72 hrs
Antiproliferative activity against human HCT116 cells after 72 hrs
|
[PMID: 18503262]
|
HCT-116
|
IC50 |
0.042 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
|
[PMID: 32650183]
|
HCT-116
|
IC50 |
0.046 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
|
[PMID: 34968813]
|
HCT-116
|
IC50 |
0.05 μM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 31655432]
|
HCT-116
|
IC50 |
0.08 μM
Compound: Colchicine
|
Cytotoxicity in human HCT-116 cells assessed as growth inhibition level after 48 hrs by SRB assay
Cytotoxicity in human HCT-116 cells assessed as growth inhibition level after 48 hrs by SRB assay
|
[PMID: 36162138]
|
HCT-116
|
IC50 |
0.081 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
HCT-116
|
IC50 |
0.083 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
HCT-116
|
IC50 |
0.108 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 35605363]
|
HCT-116
|
IC50 |
0.129 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32682200]
|
HCT-116
|
IC50 |
0.13 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34971875]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured for 24 hrs by MTT assay
|
[PMID: 36970147]
|
HCT-116
|
GI50 |
1.2 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
|
[PMID: 30288225]
|
HCT-116
|
IC50 |
1.85 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37122544]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 96 hrs
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 96 hrs
|
10.1039/C3MD00287J
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 96 hrs by microplate reader analysis
Cytotoxicity against human HCT116 cells after 96 hrs by microplate reader analysis
|
10.1039/C2MD20250F
|
HCT-116
|
IC50 |
13.9 nM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
HCT-116
|
IC50 |
13.9 nM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
HCT-116
|
IC50 |
15 nM
Compound: colchicine
|
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
HCT-116
|
IC50 |
2.13 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human HCT116 assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
HCT-116
|
IC50 |
26.18 nM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 30197030]
|
HCT-116
|
IC50 |
27.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
HCT-116
|
IC50 |
32 nM
Compound: colchicine
|
Cytotoxicity against human HCT116 cells after 72 hrs
Cytotoxicity against human HCT116 cells after 72 hrs
|
[PMID: 19530698]
|
HCT-116
|
IC50 |
5.13 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 32768647]
|
HCT-15
|
IC50 |
0.08 μM
Compound: Colchicine
|
Cytotoxicity against human HCT15 cells by MTT assay
Cytotoxicity against human HCT15 cells by MTT assay
|
[PMID: 23425970]
|
HCT-15
|
IC50 |
100 nM
Compound: colchicine
|
Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
HCT-15
|
IC50 |
16 nM
Compound: colchicine
|
Antiproliferative activity against human HCT15 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human HCT15 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
HCT-15
|
IC50 |
|
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
HCT-15
|
IC50 |
9 nM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human HCT15 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
Antiproliferative activity against human HCT15 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
|
[PMID: 31655432]
|
HCT-8
|
ED50 |
0.016 μg/mL
Compound: colchicine
|
Cytotoxicity against human ileocecal carcinoma cells (HCT-8) using SRB assay.
Cytotoxicity against human ileocecal carcinoma cells (HCT-8) using SRB assay.
|
[PMID: 9544215]
|
HCT-8
|
IC50 |
0.022 μM
Compound: Colchicine
|
Antiproliferative activity against human HCT-8 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-8 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
HCT-8
|
ED50 |
|
Cytotoxicity against human HCT8 cells after 2 days
Cytotoxicity against human HCT8 cells after 2 days
|
[PMID: 20542428]
|
HCT-8
|
IC50 |
|
Antiproliferative activity against human HCT8 cells after 48 hrs by SRB method
Antiproliferative activity against human HCT8 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
HCT-8
|
IC50 |
|
Antiproliferative activity against vincristine-resistant human HCT8 cells after 48 hrs by SRB method
Antiproliferative activity against vincristine-resistant human HCT8 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
HCT-8
|
IC50 |
11.8 μM
Compound: Colchicine
|
Cytotoxicity against taxol-resistant human HCT8 cells by MTT assay
Cytotoxicity against taxol-resistant human HCT8 cells by MTT assay
|
[PMID: 23425970]
|
HCT-8
|
IC50 |
13.4 nM
Compound: Colchicine
|
Antiproliferative activity against human HCT8 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
HCT-8
|
IC50 |
|
Cytotoxicity against vinblastine resistant/P-gp overexpressing human HCT8 cells assessed as reduction in cell growth after 24 hrs by MTT assay
Cytotoxicity against vinblastine resistant/P-gp overexpressing human HCT8 cells assessed as reduction in cell growth after 24 hrs by MTT assay
|
[PMID: 27213819]
|
HCT-8
|
IC50 |
|
Antiproliferative activity against human HCT8 cells after 24 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
HEK293
|
IC50 |
|
Cytotoxicity against human HEK293 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human HEK293 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 35694693]
|
HEK293
|
IC50 |
0.005 μM
Compound: colchicine
|
Cytotoxicity against human HEK293 cells after 3 days by MTT assay
Cytotoxicity against human HEK293 cells after 3 days by MTT assay
|
[PMID: 25426924]
|
HEK293
|
IC50 |
0.009 μM
Compound: Colchicine
|
Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay
Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay
|
[PMID: 23932339]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells after 68 hrs by MTT assay
Cytotoxicity against HEK293 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
HEK293
|
EC50 |
0.03 μM
Compound: Colchicine
|
Cytotoxicity against HEK293 cells after 48 hrs by MTS assay
Cytotoxicity against HEK293 cells after 48 hrs by MTS assay
|
[PMID: 24842619]
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells incubated for 48 hrs by MTT assay
Cytotoxicity against HEK293 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
HEK293
|
IC50 |
10.2 nM
Compound: Colchicine
|
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
HEK293
|
IC50 |
13 nM
Compound: Colchicine
|
Antiproliferative activity against human HEK293 cells after 2 days by MTT assay
Antiproliferative activity against human HEK293 cells after 2 days by MTT assay
|
[PMID: 29604583]
|
HEK293
|
IC50 |
|
Cytotoxicity against human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 33479669]
|
HEK293
|
IC50 |
|
Cytotoxicity against human HEK293 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HEK293 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
HEK293
|
IC50 |
|
Cytotoxic activity in HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxic activity in HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 29028531]
|
HEK293
|
IC50 |
5 nM
Compound: Colchicine
|
Antiproliferative activity against HEK293 cells after 2 days by MTT assay
Antiproliferative activity against HEK293 cells after 2 days by MTT assay
|
[PMID: 29550732]
|
HEK293
|
IC50 |
5 nM
Compound: Colchicine
|
Cytotoxicity against HEK293 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against HEK293 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 27915168]
|
HEK-293T
|
IC50 |
1.03 μM
Compound: Colchicine
|
Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
|
[PMID: 35367708]
|
HEK-293T
|
CC50 |
129.32 μM
Compound: Colchicine
|
Cytotoxicity against HEK293T cells after 24 hrs by MTT assay
Cytotoxicity against HEK293T cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HEK-293T
|
CC50 |
152 μM
Compound: Colchicine
|
Antiproliferative activity against human 293T cells measured after 24 hrs by MTT assay
Antiproliferative activity against human 293T cells measured after 24 hrs by MTT assay
|
10.1039/C6MD00255B
|
HEK-293T
|
IC50 |
|
Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 36760739]
|
HEK-293T
|
IC50 |
6.38 μM
Compound: Colchicine
|
Antiproliferative activity against human 293T cells after 24 hrs by MTT assay
Antiproliferative activity against human 293T cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
HEK-293T
|
CC50 |
8.43 μM
Compound: Colchicine
|
Antiproliferative activity against human HEK293T cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HEK293T cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HEK-293T
|
IC50 |
801.2 μM
Compound: Colchicine
|
Cytotoxicity against human HEK293T cells expressing ABCB1 (unknown origin) measured after 72 hrs by MTT assay
Cytotoxicity against human HEK293T cells expressing ABCB1 (unknown origin) measured after 72 hrs by MTT assay
|
[PMID: 34546748]
|
HeLa
|
IC50 |
< 1 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 20833451]
|
HeLa
|
IC50 |
|
Cytotoxicity in human HeLa cells assessed as reduction in cell viability after 4 days under dark condition by MTT assay
Cytotoxicity in human HeLa cells assessed as reduction in cell viability after 4 days under dark condition by MTT assay
|
[PMID: 29172077]
|
HeLa
|
IC50 |
0.006 μM
Compound: Colchicine
|
Cytotoxicity in human HeLa cells assessed as growth inhibition level after 48 hrs by SRB assay
Cytotoxicity in human HeLa cells assessed as growth inhibition level after 48 hrs by SRB assay
|
[PMID: 36162138]
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells incubated for 72 hrs by MTT assay
Growth inhibition of human HeLa cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
HeLa
|
IC50 |
0.008 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells measured after 3 days by Coulter counter method
Antiproliferative activity against human HeLa cells measured after 3 days by Coulter counter method
|
[PMID: 30921759]
|
HeLa
|
IC50 |
0.0087 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 3 days by coulter counting method
Antiproliferative activity against human HeLa cells after 3 days by coulter counting method
|
[PMID: 29471122]
|
HeLa
|
IC50 |
0.0087 μM
Compound: 1, colch
|
Antiproliferative activity against human HeLa cells after 4 days by coulter counter analysis
Antiproliferative activity against human HeLa cells after 4 days by coulter counter analysis
|
[PMID: 24773591]
|
HeLa
|
IC50 |
0.011 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by SRB assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by SRB assay
|
[PMID: 30883116]
|
HeLa
|
IC50 |
0.013 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31185410]
|
HeLa
|
IC50 |
0.02 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells assessed as reduction in cell growth measured after 48 hrs by WST-8 assay
Cytotoxicity against human HeLa cells assessed as reduction in cell growth measured after 48 hrs by WST-8 assay
|
[PMID: 27665177]
|
HeLa
|
IC50 |
0.023 μM
Compound: Colchicine
|
In vitro inhibitory activity against HeLa/KB cells using XTT proliferation assay.
In vitro inhibitory activity against HeLa/KB cells using XTT proliferation assay.
|
[PMID: 11741473]
|
HeLa
|
IC50 |
0.027 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 30106297]
|
HeLa
|
EC50 |
0.027 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
HeLa
|
IC50 |
0.028 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation after 4 days by Coulter counter based cell counting method
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation after 4 days by Coulter counter based cell counting method
|
[PMID: 25282265]
|
HeLa
|
IC50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth after 48 hrs by MTT assay
|
[PMID: 31753698]
|
HeLa
|
EC50 |
0.03 μM
Compound: Colchicine
|
Induction of mitotic arrest in human HeLa cells assessed as reduction in cell density by immunofluorescence staining
Induction of mitotic arrest in human HeLa cells assessed as reduction in cell density by immunofluorescence staining
|
[PMID: 22564383]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 3 days by SRB assay
Cytotoxicity against human HeLa cells after 3 days by SRB assay
|
[PMID: 26927488]
|
HeLa
|
EC50 |
0.039 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 48 hrs by luminescence cell viability assay
Cytotoxicity against human HeLa cells after 48 hrs by luminescence cell viability assay
|
[PMID: 18684625]
|
HeLa
|
GI50 |
0.04 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
|
[PMID: 25827522]
|
HeLa
|
IC50 |
|
Antiproliferation activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferation activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
HeLa
|
IC50 |
0.051 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 30093295]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 24 to 72 hrs by Cell Titer Blue assay
Cytotoxicity against human HeLa cells after 24 to 72 hrs by Cell Titer Blue assay
|
[PMID: 32432867]
|
HeLa
|
IC50 |
0.081 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
|
[PMID: 32650183]
|
HeLa
|
IC50 |
0.083 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
HeLa
|
IC50 |
0.1 μg/mL
Compound: colchicine
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 15620246]
|
HeLa
|
IC50 |
0.1 μg/mL
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 15165134]
|
HeLa
|
IC50 |
0.1 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 48 hrs
Cytotoxicity against human HeLa cells after 48 hrs
|
[PMID: 23022053]
|
HeLa
|
IC50 |
0.103 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
HeLa
|
IC50 |
0.138 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 34968813]
|
HeLa
|
IC50 |
0.15 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
|
[PMID: 35367708]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
|
[PMID: 36760739]
|
HeLa
|
IC50 |
0.36 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HeLa
|
IC50 |
0.45 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells measured after 24 hrs by MTT assay
|
10.1039/C6MD00255B
|
HeLa
|
IC50 |
0.5 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells by SRB assay
Antiproliferative activity against human HeLa cells by SRB assay
|
[PMID: 28988750]
|
HeLa
|
IC50 |
0.54 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 25499929]
|
HeLa
|
IC50 |
0.704 μM
Compound: Colchicine
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25091926]
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
HeLa
|
IC50 |
10.2 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
HeLa
|
IC50 |
14 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 2 days by MTT assay
Antiproliferative activity against human HeLa cells after 2 days by MTT assay
|
[PMID: 29604583]
|
HeLa
|
IC50 |
16 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35084853]
|
HeLa
|
IC50 |
17.79 μM
Compound: Colchicine
|
Anticancer activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 35367708]
|
HeLa
|
IC50 |
19.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
HeLa
|
IC50 |
2.54 μM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by WST-8 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST-8 assay
|
[PMID: 22727370]
|
HeLa
|
IC50 |
21 μg/mL
Compound: Colchicine
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 11473441]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
Cytotoxicity against human HeLa cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 26985296]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
HeLa
|
EC50 |
|
Antimitotic activity in human HeLa cells assessed as cell density loss after 24 hrs by Hoechst 33342 staining
Antimitotic activity in human HeLa cells assessed as cell density loss after 24 hrs by Hoechst 33342 staining
|
[PMID: 23524161]
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by CCK-8 assay
Cytotoxicity against human HeLa cells after 72 hrs by CCK-8 assay
|
[PMID: 23360369]
|
HeLa
|
IC50 |
55 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 33234343]
|
HeLa
|
IC50 |
8.2 nM
Compound: colchicine
|
Cytotoxicity against human HeLa cells after 96 hrs by MTT assay
Cytotoxicity against human HeLa cells after 96 hrs by MTT assay
|
[PMID: 23176628]
|
HeLa
|
IC50 |
8.89 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 30197030]
|
HeLa
|
IC50 |
9.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
HeLa
|
IC50 |
9.7 nM
Compound: colchicine
|
Cytotoxicity against human HeLa cells expressing class 3 tubulin after 96 hrs by MTT assay
Cytotoxicity against human HeLa cells expressing class 3 tubulin after 96 hrs by MTT assay
|
[PMID: 23176628]
|
Hep 3B2
|
IC50 |
0.014 μM
Compound: Colchicine
|
Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
Hep 3B2
|
IC50 |
0.14 μM
Compound: Colchicine
|
Antiproliferative activity against human Hep3B cells measured after 72 hrs by MTT assay
Antiproliferative activity against human Hep3B cells measured after 72 hrs by MTT assay
|
[PMID: 35193066]
|
Hepatocyte
|
CC50 |
152.78 μM
Compound: Colchicine
|
Cytotoxicity against mouse primary hepatocytes after 24 hrs by MTT assay
Cytotoxicity against mouse primary hepatocytes after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HepG2
|
IC50 |
> 10 μM
Compound: Colchicine
|
Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 23747810]
|
HepG2
|
IC50 |
0.002 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
HepG2
|
IC50 |
|
Growth inhibition of human HepG2 cells incubated for 72 hrs by MTT assay
Growth inhibition of human HepG2 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
HepG2
|
IC50 |
0.02 μM
Compound: Colchicine
|
Cytotoxicity against human HepG2 cells after 48 hrs
Cytotoxicity against human HepG2 cells after 48 hrs
|
[PMID: 23022053]
|
HepG2
|
IC50 |
0.027 μM
Compound: Colchicine
|
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
HepG2
|
EC50 |
0.031 μM
Compound: Colchicine
|
Cytotoxicity against human HepG2 cells after 48 hrs by luminescence cell viability assay
Cytotoxicity against human HepG2 cells after 48 hrs by luminescence cell viability assay
|
[PMID: 18684625]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by SRB method
Antiproliferative activity against human HepG2 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
HepG2
|
IC50 |
0.042 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 28863359]
|
HepG2
|
IC50 |
0.046 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 30093295]
|
HepG2
|
IC50 |
0.05 μM
Compound: Colchicin
|
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 21724404]
|
HepG2
|
IC50 |
0.054 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 36455508]
|
HepG2
|
IC50 |
0.064 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 34968813]
|
HepG2
|
IC50 |
0.078 μM
Compound: Colchicine
|
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 30106297]
|
HepG2
|
IC50 |
0.1239 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by SRB assay
Antiproliferative activity against human HepG2 cells after 48 hrs by SRB assay
|
[PMID: 27744186]
|
HepG2
|
IC50 |
0.23 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 21440448]
|
HepG2
|
IC50 |
0.23 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
HepG2
|
IC50 |
0.42 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
HepG2
|
IC50 |
0.64 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 24 hrs by MTT assay
|
10.1039/C6MD00255B
|
HepG2
|
IC50 |
1.47 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HepG2
|
IC50 |
1.71 μM
Compound: Colchicine
|
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25091926]
|
HepG2
|
IC50 |
1.8 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 25778766]
|
HepG2
|
IC50 |
1.8 μM
Compound: Colchicin
|
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23735826]
|
HepG2
|
IC50 |
1.9 μM
Compound: Colchicin
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 21576023]
|
HepG2
|
GI50 |
10.5 μM
Compound: Colchicine
|
Growth inhibition of human HepG2 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human HepG2 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
HepG2
|
IC50 |
13.6 nM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
HepG2
|
IC50 |
4.6 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
|
[PMID: 30690300]
|
HepG2
|
IC50 |
4.65 μM
Compound: Colchicine
|
Anticancer activity against human HepG2 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 35367708]
|
HepG2
|
IC50 |
4.65 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
HepG2
|
IC50 |
42 nM
Compound: colchicine
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
HepG2
|
IC50 |
45 nM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 33234343]
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells after 72 hrs by CCK-8 assay
Cytotoxicity against human HepG2 cells after 72 hrs by CCK-8 assay
|
[PMID: 23360369]
|
HepG2
|
IC50 |
5.8 μM
Compound: Colchicine
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
HGC-27
|
IC50 |
0.003 μM
Compound: Colchicine
|
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
HL-60
|
IC50 |
|
Cytotoxicity against vincristine-resistant human HL60 cells after 72 hrs MTS assay
Cytotoxicity against vincristine-resistant human HL60 cells after 72 hrs MTS assay
|
[PMID: 20411988]
|
HL-60
|
EC50 |
0.0086 μM
Compound: Colchicine
|
Antiproliferative activity against human HL60 cells after 96 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells after 72 hrs MTS assay
Cytotoxicity against human HL60 cells after 72 hrs MTS assay
|
[PMID: 20411988]
|
HL-60
|
IC50 |
1.6 μg/mL
Compound: colchicine
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 15620246]
|
HL-60
|
IC50 |
1.6 μg/mL
Compound: Colchicine
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 15165134]
|
HMEC
|
IC50 |
8.1 μM
Compound: Colchicine
|
Antiproliferative activity against human HMEC cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HMEC cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
HMEC-1
|
IC50 |
|
Antiproliferative activity against human HMEC1 cells measured after 4 days by Coulter counter method
Antiproliferative activity against human HMEC1 cells measured after 4 days by Coulter counter method
|
[PMID: 30921759]
|
HMEC-1
|
IC50 |
0.0038 μM
Compound: Colchicine
|
Antiproliferative activity against human HMEC1 cells after 4 days by coulter counting method
Antiproliferative activity against human HMEC1 cells after 4 days by coulter counting method
|
[PMID: 29471122]
|
HMEC-1
|
IC50 |
0.0038 μM
Compound: Colchicine
|
Antiproliferative activity against human HMEC1 cells assessed as inhibition of cell proliferation after 4 days by Coulter counter based cell counting method
Antiproliferative activity against human HMEC1 cells assessed as inhibition of cell proliferation after 4 days by Coulter counter based cell counting method
|
[PMID: 25282265]
|
HMEC-1
|
IC50 |
0.0038 μM
Compound: 1, colch
|
Antiproliferative activity against HMEC1 after 4 days by coulter counter analysis
Antiproliferative activity against HMEC1 after 4 days by coulter counter analysis
|
[PMID: 24773591]
|
HN-6
|
IC50 |
19.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HN-6 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HN-6 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 35576703]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 after 48 hrs by SRB assay
Antiproliferative activity against human HT1080 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HT1080 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
HT-1080
|
IC50 |
|
Cytotoxicity against human HT1080 cells after 72 hrs by CCK-8 assay
Cytotoxicity against human HT1080 cells after 72 hrs by CCK-8 assay
|
[PMID: 23360369]
|
HT-29
|
IC50 |
< 1 μM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 20833451]
|
HT-29
|
GI50 |
|
Antiproliferative activity against human HT29 cells after 48 hrs by sulforhodamine B method
Antiproliferative activity against human HT29 cells after 48 hrs by sulforhodamine B method
|
[PMID: 18617414]
|
HT-29
|
GI50 |
0.004 μM
Compound: colchicine
|
Growth inhibition of human HT29 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HT29 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 18579387]
|
HT-29
|
GI50 |
0.004 μM
Compound: colchicine
|
Growth inhibition of human HT29 cells after 48 hrs
Growth inhibition of human HT29 cells after 48 hrs
|
[PMID: 17498960]
|
HT-29
|
IC50 |
0.008 μM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells by MTS assay
Antiproliferative activity against human HT-29 cells by MTS assay
|
10.1039/C3MD00077J
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
|
[PMID: 24900316]
|
HT-29
|
IC50 |
0.01 μM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay
|
[PMID: 22542017]
|
HT-29
|
IC50 |
0.018 μM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells over expressing GLUT1 measured after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells over expressing GLUT1 measured after 72 hrs by MTT assay
|
[PMID: 35193066]
|
HT-29
|
IC50 |
0.02 μM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells by MTT assay
Cytotoxicity against human HT-29 cells by MTT assay
|
[PMID: 23425970]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
HT-29
|
IC50 |
0.05 μM
Compound: colchicine
|
Cytotoxicity against human HT-29 cells after 3 days by MTT assay
Cytotoxicity against human HT-29 cells after 3 days by MTT assay
|
[PMID: 25426924]
|
HT-29
|
IC50 |
0.07 μM
Compound: Colchicine
|
Growth inhibition of human HT-29 cells after 72 hrs by MTT assay
Growth inhibition of human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 23747810]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
|
[PMID: 36760739]
|
HT-29
|
IC50 |
0.25 μM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
HT-29
|
IC50 |
1.81 μM
Compound: Colchicine
|
Antiproliferative activity against human HT29 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HT29 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
HT-29
|
IC50 |
10 nM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue dye assay
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19586033]
|
HT-29
|
IC50 |
|
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19053773]
|
HT-29
|
IC50 |
11.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
HT-29
|
IC50 |
12.8 nM
Compound: colchicine
|
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay
Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
HT-29
|
IC50 |
13 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
|
[PMID: 29604583]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
|
10.1039/C0MD00052C
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
|
[PMID: 24106982]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 48 hrs by resazurin assay
Cytotoxicity against human HT-29 cells after 48 hrs by resazurin assay
|
[PMID: 22727370]
|
HT-29
|
IC50 |
16 nM
Compound: colchicine
|
Cytotoxicity against human HT-29 cells after 48 hrs using resazurin by microplate fluorometer analysis
Cytotoxicity against human HT-29 cells after 48 hrs using resazurin by microplate fluorometer analysis
|
[PMID: 22185476]
|
HT-29
|
IC50 |
|
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue assay
Growth inhibition of human HT-29 cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
HT-29
|
IC50 |
16.6 nM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells after 72 hrs by XTT/PMS method
Cytotoxicity against human HT-29 cells after 72 hrs by XTT/PMS method
|
[PMID: 21106379]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23214452]
|
HT-29
|
IC50 |
18 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
|
[PMID: 2778449]
|
HT-29
|
IC50 |
20.5 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
HT-29
|
IC50 |
21.9 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
HT-29
|
IC50 |
5.19 μM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 32768647]
|
HT-29
|
IC50 |
50 nM
Compound: Colchicine
|
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
Antiproliferative activity against human HT-29 cells after 2 days by MTT assay
|
[PMID: 29550732]
|
HT-29
|
IC50 |
50 nM
Compound: Colchicine
|
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 27915168]
|
HT-29
|
IC50 |
69.25 nM
Compound: colchicine
|
Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay
|
[PMID: 23176628]
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 96 hrs
Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 96 hrs
|
10.1039/C3MD00287J
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 96 hrs by microplate reader analysis
Cytotoxicity against human HT-29 cells after 96 hrs by microplate reader analysis
|
10.1039/C2MD20250F
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 48 hrs by XTT assay
Cytotoxicity against human HT-29 cells after 48 hrs by XTT assay
|
[PMID: 22727370]
|
Huh-7
|
IC50 |
26.1 nM
Compound: Colchicine
|
Antiproliferative activity against human Huh-7 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human Huh-7 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
HUVEC
|
IC50 |
> 10000 nM
Compound: Colchicine
|
Antiproliferative activity against HUVEC after 72 hrs by MTS assay
Antiproliferative activity against HUVEC after 72 hrs by MTS assay
|
[PMID: 30099258]
|
HUVEC
|
IC50 |
0.012 μM
Compound: Colchicine
|
Cytotoxicity against HUVEC measured after 72 hrs by MTT assay
Cytotoxicity against HUVEC measured after 72 hrs by MTT assay
|
[PMID: 35193066]
|
HUVEC
|
IC50 |
|
Cytotoxicity against human HUVEC cells after 24 hrs by MTT assay
Cytotoxicity against human HUVEC cells after 24 hrs by MTT assay
|
[PMID: 23524161]
|
HUVEC
|
IC50 |
0.025 μM
Compound: Colchicine
|
Anti-angiogenesis activity against HUVEC cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Anti-angiogenesis activity against HUVEC cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC assessed as cell viability after 4 days by MTS assay
Cytotoxicity against HUVEC assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
HUVEC
|
GI50 |
25 nM
Compound: Colchicine
|
Growth inhibition of HUVEC after 72 hrs by crystal violet staining-based assay
Growth inhibition of HUVEC after 72 hrs by crystal violet staining-based assay
|
[PMID: 27690431]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against quesicent HUVECs after 48 hrs by CCK-8 assay
Antiproliferative activity against quesicent HUVECs after 48 hrs by CCK-8 assay
|
[PMID: 23360369]
|
HUVEC
|
IC50 |
|
Antiproliferative activity against activated HUVECs after 48 hrs by CCK-8 assay
Antiproliferative activity against activated HUVECs after 48 hrs by CCK-8 assay
|
[PMID: 23360369]
|
J774
|
IC50 |
0.21 μM
Compound: colchicine
|
Cytotoxicity against mouse J774 cells by alamar blue assay
Cytotoxicity against mouse J774 cells by alamar blue assay
|
[PMID: 17637068]
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells after 48 hrs by MTT assay
Cytotoxicity against human Jurkat cells after 48 hrs by MTT assay
|
[PMID: 23524161]
|
Jurkat
|
IC50 |
|
Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human Jurkat cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
Cytotoxicity against human Jurkat cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 26985296]
|
Jurkat
|
IC50 |
19.8 nM
Compound: Colchicine
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTS assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
K562
|
IC50 |
0.001 μM
Compound: Colchicine
|
Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25091926]
|
K562
|
IC50 |
0.013 μM
Compound: Colchicine
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 33212157]
|
K562
|
GI50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 28763647]
|
K562
|
IC50 |
|
Growth inhibition of human K562 cells after 48 hrs by trypan blue assay
Growth inhibition of human K562 cells after 48 hrs by trypan blue assay
|
[PMID: 21530013]
|
K562
|
IC50 |
0.02 μM
Compound: Colchicine
|
Growth inhibition of human K562 cells after 24 hrs by trypan blue exclusion assay
Growth inhibition of human K562 cells after 24 hrs by trypan blue exclusion assay
|
[PMID: 23747810]
|
K562
|
IC50 |
0.02 μM
Compound: Colchicine
|
Growth inhibition of human K562 cells incubated for 24 hrs by trypan blue dye exclusion assay
Growth inhibition of human K562 cells incubated for 24 hrs by trypan blue dye exclusion assay
|
[PMID: 26344588]
|
K562
|
IC50 |
0.02 μM
Compound: colchicine
|
Antiproliferative activity against human K562 cells after 48 hrs by Alamar blue dye based neubauer hemocytometer method
Antiproliferative activity against human K562 cells after 48 hrs by Alamar blue dye based neubauer hemocytometer method
|
[PMID: 28045256]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometer
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometer
|
[PMID: 21705223]
|
K562
|
IC50 |
0.02 μM
Compound: colchicine
|
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
|
[PMID: 21563750]
|
K562
|
IC50 |
|
Cell growth inhibition of human K562 cells after 48 hrs
Cell growth inhibition of human K562 cells after 48 hrs
|
[PMID: 20546980]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs
Antiproliferative activity against human K562 cells after 48 hrs
|
[PMID: 20537765]
|
K562
|
IC50 |
0.02 μM
Compound: colchicine
|
Antiproliferative activity against human K562 cells after 48 hrs
Antiproliferative activity against human K562 cells after 48 hrs
|
[PMID: 19220018]
|
K562
|
IC50 |
0.02 μM
Compound: colchicine
|
Antiproliferative activity against human K562 cells after 48 hrs
Antiproliferative activity against human K562 cells after 48 hrs
|
[PMID: 17973361]
|
K562
|
IC50 |
0.44 μM
Compound: Colchicine
|
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
K562
|
IC50 |
0.55 μM
Compound: Colchicine
|
Cytotoxicity against human K562 cells after 48 hrs
Cytotoxicity against human K562 cells after 48 hrs
|
[PMID: 23022053]
|
K562
|
IC50 |
101.8 nM
Compound: Colchicine
|
Antiproliferative activity against human K562 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human K562 cells measured after 72 hrs by SRB assay
|
[PMID: 34794817]
|
K562
|
IC50 |
16 nM
Compound: colchicine
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells assessed as growth inhibition after 5 days by MTT assay
Cytotoxicity against human K562 cells assessed as growth inhibition after 5 days by MTT assay
|
[PMID: 28143677]
|
K562
|
IC50 |
29 nM
Compound: colchicine
|
Cytotoxicity against human K562 cells after 72 hrs
Cytotoxicity against human K562 cells after 72 hrs
|
[PMID: 19530698]
|
K562
|
IC50 |
6.59 μM
Compound: Colchicine
|
Antiproliferative activity against drug resistant human K562 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against drug resistant human K562 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 after 48 hrs by SRB assay
Antiproliferative activity against human K562 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human K562 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
K562/Adr
|
IC50 |
6553 nM
Compound: Colchicine
|
Antiproliferative activity against human K562/Adr cells measured after 72 hrs by SRB assay
Antiproliferative activity against human K562/Adr cells measured after 72 hrs by SRB assay
|
[PMID: 34794817]
|
KB
|
ED50 |
0.002 μg/mL
Compound: colchicine
|
Cytotoxicity against human epidermoid carcinoma of the nasopharyngeal cells (KB) using SRB assay.
Cytotoxicity against human epidermoid carcinoma of the nasopharyngeal cells (KB) using SRB assay.
|
[PMID: 9544215]
|
KB
|
ED50 |
|
Cytotoxicity against human KB cells after 2 days
Cytotoxicity against human KB cells after 2 days
|
[PMID: 20542428]
|
KB
|
IC50 |
0.01 μM
Compound: colchicine
|
Antiproliferative activity against human KB/HeLa cells by XTT assay
Antiproliferative activity against human KB/HeLa cells by XTT assay
|
[PMID: 19220018]
|
KB
|
IC50 |
0.013 μM
Compound: Colchicine
|
Cytotoxicity against human KB cells after 48 hrs by MTT assay
Cytotoxicity against human KB cells after 48 hrs by MTT assay
|
[PMID: 20363142]
|
KB
|
IC50 |
0.02 μM
Compound: 1, colchicine
|
Cytotoxicity against human KB cells after 72 hrs
Cytotoxicity against human KB cells after 72 hrs
|
[PMID: 18503262]
|
KB
|
IC50 |
|
Cytotoxicity against human KB/HeLa cells after 48 hrs by XTT assay
Cytotoxicity against human KB/HeLa cells after 48 hrs by XTT assay
|
[PMID: 21705223]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB/HeLa cells after 48 hrs by XTT assay
Antiproliferative activity against human KB/HeLa cells after 48 hrs by XTT assay
|
[PMID: 20537765]
|
KB
|
IC50 |
0.03 μM
Compound: colchicine
|
Cytotoxicity against human KB/HeLa cells after 48 hrs by XTT assay
Cytotoxicity against human KB/HeLa cells after 48 hrs by XTT assay
|
[PMID: 17973361]
|
KB
|
IC50 |
|
Antiproliferative activity against KB/HeLa cells by XTT assay after 48 hrs
Antiproliferative activity against KB/HeLa cells by XTT assay after 48 hrs
|
[PMID: 17181164]
|
KB
|
IC50 |
0.03 μM
Compound: 2 (Colchicine)
|
Cytotoxic activity against cellular metabolic activity of Cervix KB/HeLa tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
Cytotoxic activity against cellular metabolic activity of Cervix KB/HeLa tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
|
[PMID: 12852768]
|
KB
|
ED50 |
0.2 μg/mL
Compound: Colchicine
|
Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
|
[PMID: 7528785]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
KB
|
EC50 |
10 nM
Compound: Colchicine
|
Cell cycle arrest in human KB cells assessed as accumulation of cells at G2/M phase after 24 hrs by propidium iodide-based FACScan
Cell cycle arrest in human KB cells assessed as accumulation of cells at G2/M phase after 24 hrs by propidium iodide-based FACScan
|
[PMID: 21480626]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
Antiproliferative activity against human KB cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
|
10.1039/C0MD00052C
|
KB
|
IC50 |
|
Growth inhibition of human KB cells after 72 hrs by methylene blue assay
Growth inhibition of human KB cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
KB
|
IC50 |
|
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
|
[PMID: 24106982]
|
KB
|
IC50 |
11 nM
Compound: Colchicine
|
Cytotoxicity against human KB cells after 72 hrs by methylene blue dye assay
Cytotoxicity against human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 19586033]
|
KB
|
IC50 |
|
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 19053773]
|
KB
|
IC50 |
|
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
KB
|
IC50 |
|
Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-VIN10 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-VIN10 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19053773]
|
KB
|
IC50 |
117 nM
Compound: Colchicine
|
Cytotoxicity against KB-VIN 10 cell line by methylene blue dye assay
Cytotoxicity against KB-VIN 10 cell line by methylene blue dye assay
|
[PMID: 17154496]
|
KB
|
IC50 |
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
KB
|
IC50 |
12 nM
Compound: colchichine
|
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay
|
[PMID: 17685504]
|
KB
|
IC50 |
12.4 nM
Compound: Colchicine
|
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 26160020]
|
KB
|
IC50 |
12.4 nM
Compound: colchicine
|
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay
Cytotoxicity against human KB cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
KB
|
IC50 |
13.3 nM
Compound: Colchicine
|
Cytotoxicity against human KB cell line by methylene blue dye assay
Cytotoxicity against human KB cell line by methylene blue dye assay
|
[PMID: 17154496]
|
KB
|
EC50 |
|
Cell cycle arrest in human KB/HeLa cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human KB/HeLa cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 20537765]
|
KB
|
EC50 |
14 nM
Compound: colchicine
|
Cell cycle arrest in human KB/HeLa cells assessed as G2/M phase accumulation after 24 hrs by FACS analysis
Cell cycle arrest in human KB/HeLa cells assessed as G2/M phase accumulation after 24 hrs by FACS analysis
|
[PMID: 19220018]
|
KB
|
EC50 |
|
Cell cycle arrest in human KB/HeLa cells assessed as accumulation of cells at G2/M phase after 24 hrs by flow cytometry
Cell cycle arrest in human KB/HeLa cells assessed as accumulation of cells at G2/M phase after 24 hrs by flow cytometry
|
[PMID: 21705223]
|
KB
|
EC50 |
14 nM
Compound: colchicine
|
Cell cycle arrest in KB/HeLa cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis
Cell cycle arrest in KB/HeLa cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis
|
[PMID: 17973361]
|
KB
|
EC50 |
|
Cell cycle arrest in KB/HeLa cells by accumulation at G2/M phase
Cell cycle arrest in KB/HeLa cells by accumulation at G2/M phase
|
[PMID: 17181164]
|
KB
|
IC50 |
18.2 nM
Compound: Colchicine
|
Antiproliferative activity against human KB cells measured after 72 hrs by SRB assay
Antiproliferative activity against human KB cells measured after 72 hrs by SRB assay
|
[PMID: 34794817]
|
KB
|
GI50 |
4.2 nM
Compound: Colchicine
|
Growth inhibition of human KB cells after 72 hrs by MTS assay
Growth inhibition of human KB cells after 72 hrs by MTS assay
|
[PMID: 26778612]
|
KB 3-1
|
IC50 |
0.018 μM
Compound: Colchicine
|
Cytotoxicity against human KB-3-1 cells after 72 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells after 72 hrs by MTT assay
|
[PMID: 23932339]
|
KB 3-1
|
IC50 |
|
Cytotoxicity against human KB3-1 cells after 68 hrs by MTT assay
Cytotoxicity against human KB3-1 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
KB 3-1
|
IC50 |
|
Antiproliferative activity against human KB-31 cells incubated for 96 hrs by spectrophotometric method
Antiproliferative activity against human KB-31 cells incubated for 96 hrs by spectrophotometric method
|
[PMID: 32432867]
|
KB-V1
|
IC50 |
1340 nM
Compound: Colchicine
|
Antiproliferative activity against human KB-V1 cells measured after 72 hrs by SRB assay
Antiproliferative activity against human KB-V1 cells measured after 72 hrs by SRB assay
|
[PMID: 34794817]
|
KYSE-30
|
IC50 |
0.28 μM
Compound: Colchicine
|
Antiproliferative activity against human KYSE-30 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
Antiproliferative activity against human KYSE-30 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
|
[PMID: 34022412]
|
KYSE-30
|
IC50 |
0.28 μM
Compound: Colchicine
|
Antiproliferative activity against human KYSE-30 cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human KYSE-30 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 33965530]
|
KYSE-450
|
IC50 |
0.077 μM
Compound: Colchicine
|
Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
KYSE-450
|
IC50 |
0.122 μM
Compound: Colchicine
|
Antiproliferative activity against human KYSE-450 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human KYSE-450 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 35605363]
|
KYSE-450
|
IC50 |
0.22 μM
Compound: Colchicine
|
Antiproliferative activity against human KYSE-450 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human KYSE-450 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34971875]
|
L02
|
IC50 |
2.3 μM
Compound: Colchicine
|
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
|
[PMID: 35367708]
|
L02
|
IC50 |
26.5 nM
Compound: Colchicine
|
Antiproliferative activity against human LO2 cells after 48 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
L02
|
IC50 |
3.01 μM
Compound: Colchicine
|
Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 36760739]
|
L02
|
CC50 |
9.18 μM
Compound: Colchicine
|
Antiproliferative activity against human LO2 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human LO2 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
L02
|
IC50 |
9.2 μM
Compound: Colchicine
|
Antiproliferative activity against human HL7702 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HL7702 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
L1210
|
IC50 |
0.007 μM
Compound: Colchicine
|
Antiproliferative activity against mouse L1210 cells after 96 hrs by coulter counting method
Antiproliferative activity against mouse L1210 cells after 96 hrs by coulter counting method
|
[PMID: 29471122]
|
L1210
|
IC50 |
0.01 μM
Compound: 1, colch
|
Antiproliferative activity against mouse L1210 cells after 48 to 96 hrs by coulter counter analysis
Antiproliferative activity against mouse L1210 cells after 48 to 96 hrs by coulter counter analysis
|
[PMID: 24773591]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells measured after 96 hrs by Coulter counter method
Antiproliferative activity against mouse L1210 cells measured after 96 hrs by Coulter counter method
|
[PMID: 30921759]
|
L1210
|
IC50 |
0.014 μM
Compound: Colchicine
|
Antiproliferative activity against mouse L1210 assessed as inhibition of cell proliferation after 48 hrs by Coulter counter based cell counting method
Antiproliferative activity against mouse L1210 assessed as inhibition of cell proliferation after 48 hrs by Coulter counter based cell counting method
|
[PMID: 25282265]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 after 48 hrs by SRB assay
Antiproliferative activity against mouse L1210 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against mouse L1210 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
L929
|
IC50 |
|
Antiproliferative activity against mouse L929 cells after 72 hrs by MTT assay
Antiproliferative activity against mouse L929 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
LCLC-103H cell line
|
EC50 |
0.07 μM
Compound: Colchicine
|
Antiproliferative activity against human LCLC-103H cells after 96 hrs by MTT assay
Antiproliferative activity against human LCLC-103H cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
LLC-PK1
|
IC50 |
> 50 μM
Compound: Colchicine
|
Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
|
[PMID: 12699389]
|
LLC-PK1
|
IC50 |
> 50 μM
Compound: Colchicine
|
Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
|
[PMID: 12699389]
|
LLC-PK1
|
IC50 |
> 50 μM
Compound: Colchicine
|
Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay
|
[PMID: 12699389]
|
LNCaP
|
IC50 |
0.016 μM
Compound: colchicine
|
Cytotoxicity against human LNCAP cells after 48 hrs by SRB assay
Cytotoxicity against human LNCAP cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
LNCaP
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human LNCAP cells after 96 hrs by SRB assay
Antiproliferative activity against human LNCAP cells after 96 hrs by SRB assay
|
[PMID: 22608389]
|
LNCaP
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human LNCAP cells after 96 hrs by sulforhodamine B assay
Antiproliferative activity against human LNCAP cells after 96 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
LNCaP
|
ED50 |
0.06 μg/mL
Compound: Colchicine
|
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
|
[PMID: 7528785]
|
LNCaP
|
IC50 |
16 nM
Compound: Colchicine
|
Cytotoxicity against human LNCAP cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human LNCAP cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
LNCaP
|
IC50 |
16.3 nM
Compound: Colchicine
|
Antiproliferative activity against human LNCAP cells after 48 hrs by SRB assay
Antiproliferative activity against human LNCAP cells after 48 hrs by SRB assay
|
[PMID: 22783954]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells incubated for 72 hrs by sulforhodamine B assay
Antiproliferative activity against human LoVo cells incubated for 72 hrs by sulforhodamine B assay
|
[PMID: 32432867]
|
LoVo
|
IC50 |
0.101 μM
Compound: Colchicine
|
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
|
[PMID: 21536450]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells incubated for 72 hrs by SRB assay
Antiproliferative activity against human LoVo cells incubated for 72 hrs by SRB assay
|
[PMID: 33465696]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
Antiproliferative activity against human LoVo cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
|
[PMID: 31653441]
|
LoVo
|
IC50 |
|
Cytotoxicity against human LoVo cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human LoVo cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
Antiproliferative activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
|
[PMID: 34592435]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as inhibition of proliferation after 72 hrs by SRB assay
Antiproliferative activity against human LoVo cells assessed as inhibition of proliferation after 72 hrs by SRB assay
|
[PMID: 34116158]
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
Antiproliferative activity against human LoVo cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
|
[PMID: 33611191]
|
Lu1
|
ED50 |
0.2 μg/mL
Compound: Colchicine
|
Cytotoxicity against human Lu1 cells after 3 days by SRB assay
Cytotoxicity against human Lu1 cells after 3 days by SRB assay
|
[PMID: 7528785]
|
M14
|
IC50 |
> 1 μM
Compound: Colchicine
|
Cytotoxicity against paclitaxel resistant human M14 cells measured after 72 hrs by western blot
Cytotoxicity against paclitaxel resistant human M14 cells measured after 72 hrs by western blot
|
[PMID: 34378386]
|
M14
|
IC50 |
10.6 nM
Compound: Colchicine
|
Cytotoxicity against human M14 cells measured after 72 hrs by western blot
Cytotoxicity against human M14 cells measured after 72 hrs by western blot
|
[PMID: 34378386]
|
M14
|
IC50 |
13.7 nM
Compound: Colchicine
|
Antiproliferative activity against human M14 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human M14 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
M14
|
IC50 |
16.6 nM
Compound: Colchicine
|
Antiproliferative activity against human M14 cells after 72 hrs by MTT assay
Antiproliferative activity against human M14 cells after 72 hrs by MTT assay
|
[PMID: 31251599]
|
M14
|
IC50 |
6.5 nM
Compound: Colchicine
|
Cytotoxicity against human M14 cells after 72 hrs by MTS assay
Cytotoxicity against human M14 cells after 72 hrs by MTS assay
|
[PMID: 29406710]
|
M14
|
IC50 |
9.3 nM
Compound: Colchicine
|
Antiproliferative activity against human M14 cells measured after 72 hrs by MTS assay
Antiproliferative activity against human M14 cells measured after 72 hrs by MTS assay
|
[PMID: 31860298]
|
M21
|
GI50 |
|
Antiproliferative activity against human M21 cells after 48 hrs by sulforhodamine B method
Antiproliferative activity against human M21 cells after 48 hrs by sulforhodamine B method
|
[PMID: 18617414]
|
M21
|
GI50 |
0.015 μM
Compound: colchicine
|
Growth inhibition of human M21 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human M21 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 18579387]
|
M21
|
GI50 |
0.015 μM
Compound: colchicine
|
Growth inhibition of human M21 cells after 48 hrs
Growth inhibition of human M21 cells after 48 hrs
|
[PMID: 17498960]
|
MCF-10A
|
IC50 |
0.006 μM
Compound: Colchicine
|
Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34670362]
|
MCF7
|
GI50 |
< 0.05 μM
Compound: colchicine
|
Compound was evaluated for growth inhibition against MCF-7 cells using cellular assay
Compound was evaluated for growth inhibition against MCF-7 cells using cellular assay
|
[PMID: 9871709]
|
MCF7
|
ED50 |
> 0.4 μg/mL
Compound: colchicine
|
Cytotoxicity against human breast cancer cells (MCF-7) using SRB assay.
Cytotoxicity against human breast cancer cells (MCF-7) using SRB assay.
|
[PMID: 9544215]
|
MCF7
|
IC50 |
> 300 nM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
|
[PMID: 31655432]
|
MCF7
|
IC50 |
0.006 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B method
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B method
|
[PMID: 18617414]
|
MCF7
|
GI50 |
0.009 μM
Compound: colchicine
|
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 18579387]
|
MCF7
|
GI50 |
0.009 μM
Compound: colchicine
|
Growth inhibition of human MCF7 cells after 48 hrs
Growth inhibition of human MCF7 cells after 48 hrs
|
[PMID: 17498960]
|
MCF7
|
IC50 |
0.012 μM
Compound: colchicine
|
Cytotoxicity against human MCF7 cells after 3 days by MTT assay
Cytotoxicity against human MCF7 cells after 3 days by MTT assay
|
[PMID: 25426924]
|
MCF7
|
IC50 |
0.012 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 28863359]
|
MCF7
|
IC50 |
0.013 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
|
[PMID: 23220647]
|
MCF7
|
IC50 |
0.0134 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet biomass reduction assay
Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet biomass reduction assay
|
[PMID: 20334421]
|
MCF7
|
EC50 |
|
Cytotoxicity against human MCF7 after 3 days by SRB assay
Cytotoxicity against human MCF7 after 3 days by SRB assay
|
[PMID: 15730238]
|
MCF7
|
IC50 |
0.017 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 21036623]
|
MCF7
|
IC50 |
0.017 μM
Compound: colchicine
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 20493717]
|
MCF7
|
IC50 |
0.017 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 23602523]
|
MCF7
|
IC50 |
0.018 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay
|
[PMID: 32650183]
|
MCF7
|
IC50 |
0.018 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34571171]
|
MCF7
|
IC50 |
0.019 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 23932339]
|
MCF7
|
IC50 |
0.021 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 33788562]
|
MCF7
|
IC50 |
0.028 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 34968813]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
MCF7
|
IC50 |
0.043 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells over expressing GLUT1 measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells over expressing GLUT1 measured after 72 hrs by MTT assay
|
[PMID: 35193066]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
MCF7
|
IC50 |
0.048 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 34175541]
|
MCF7
|
IC50 |
0.05 μM
Compound: Colchicine
|
Cytotoxicity in human MCF7 cells assessed as growth inhibition level after 48 hrs by SRB assay
Cytotoxicity in human MCF7 cells assessed as growth inhibition level after 48 hrs by SRB assay
|
[PMID: 36162138]
|
MCF7
|
IC50 |
0.05 μM
Compound: Colchicine
|
Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay
Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay
|
[PMID: 28006904]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by sulforhodamine B assay
|
[PMID: 32432867]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 68 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
MCF7
|
EC50 |
0.061 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
|
[PMID: 29055869]
|
MCF7
|
IC50 |
0.07 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 25499929]
|
MCF7
|
IC50 |
0.072 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 27608432]
|
MCF7
|
IC50 |
0.11 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MCF7
|
IC50 |
0.1504 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 27744186]
|
MCF7
|
IC50 |
0.16 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB method
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
MCF7
|
IC50 |
0.22 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs in presence of foetal bovine serum by MTT assay
|
[PMID: 35367708]
|
MCF7
|
IC50 |
0.29 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
|
[PMID: 23425970]
|
MCF7
|
IC50 |
0.33 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 30389289]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24916028]
|
MCF7
|
IC50 |
0.39 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 25703297]
|
MCF7
|
GI50 |
0.4 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
|
[PMID: 30288225]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay
|
[PMID: 36760739]
|
MCF7
|
IC50 |
0.44 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 30606674]
|
MCF7
|
IC50 |
0.51 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22503741]
|
MCF7
|
IC50 |
0.52 μM
Compound: Colchicine
|
Antiproliferative activity against drug-resistant human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against drug-resistant human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MCF7
|
IC50 |
0.53 μg/mL
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22261027]
|
MCF7
|
IC50 |
0.53 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22512906]
|
MCF7
|
IC50 |
0.54 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
|
10.1039/C6MD00255B
|
MCF7
|
IC50 |
1.9 μM
Compound: Colchicin
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 21576023]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by SRB assay
|
[PMID: 34592435]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by SRB assay
|
[PMID: 33611191]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining
Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining
|
[PMID: 20529690]
|
MCF7
|
IC50 |
12 nM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
|
[PMID: 29550732]
|
MCF7
|
IC50 |
12 nM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 27915168]
|
MCF7
|
IC50 |
|
Anti tumor activity on human breast cancer cell line MDR-positive MCF-7 ADRr after 72 hours of treatment
Anti tumor activity on human breast cancer cell line MDR-positive MCF-7 ADRr after 72 hours of treatment
|
[PMID: 10602712]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF-7 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
Antiproliferative activity against human MCF-7 cells assessed as inhibition of proliferation after 72 hrs by SRB assay
|
[PMID: 34116158]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 48 hrs
Growth inhibition of human MCF7 cells after 48 hrs
|
[PMID: 17497841]
|
MCF7
|
IC50 |
13 nM
Compound: colchicine
|
Growth inhibition of human MCF7 cells assessed as G2/M DNA content after 48 hrs
Growth inhibition of human MCF7 cells assessed as G2/M DNA content after 48 hrs
|
[PMID: 15566282]
|
MCF7
|
IC50 |
13.4 nM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
MCF7
|
GI50 |
13.5 μM
Compound: Colchicine
|
Growth inhibition of human MCF7 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
Growth inhibition of human MCF7 cells assessed as inhibition of cell proliferation after 24 hrs by MTT assay
|
[PMID: 26070164]
|
MCF7
|
IC50 |
14.3 μM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
MCF7
|
IC50 |
2.8 μM
Compound: Colchicine
|
Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay
Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay
|
[PMID: 28006904]
|
MCF7
|
IC50 |
2.8 μM
Compound: Colchicine
|
Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay
Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay
|
[PMID: 28006904]
|
MCF7
|
IC50 |
20 nM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
Antiproliferative activity against human MCF7 cells after 2 days by MTT assay
|
[PMID: 29604583]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF-7 cells incubated for 72 hrs by SRB assay
Antiproliferative activity against human MCF-7 cells incubated for 72 hrs by SRB assay
|
[PMID: 33465696]
|
MCF7
|
IC50 |
24.98 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells treated for 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells treated for 72 hrs by MTT assay
|
[PMID: 35344904]
|
MCF7
|
IC50 |
|
Antiproliferative activity against doxorubicin-resistant human MCF7 cells after 48 hrs by SRB method
Antiproliferative activity against doxorubicin-resistant human MCF7 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
MCF7
|
IC50 |
38 nM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 33234343]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
MCF7
|
IC50 |
5 nM
Compound: Colchicine
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 96 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 96 hrs by MTT assay
|
[PMID: 31727471]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 3 days by trypan blue exclusion assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 3 days by trypan blue exclusion assay
|
[PMID: 28523104]
|
MCF7
|
IC50 |
5 nM
Compound: Colchicine
|
Growth inhibition of human MCF7 cells after 96 hrs by trypan blue exclusion assay
Growth inhibition of human MCF7 cells after 96 hrs by trypan blue exclusion assay
|
[PMID: 29730191]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition by trypan blue exclusion assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition by trypan blue exclusion assay
|
[PMID: 23214452]
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human MCF7 cells after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
MCF7
|
IC50 |
|
Growth inhibition of human MCF7 cells after 96 hrs
Growth inhibition of human MCF7 cells after 96 hrs
|
[PMID: 22044164]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 35694693]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 120 hrs by MTT assay
|
[PMID: 31653441]
|
MCF7
|
IC50 |
58 nM
Compound: colchicine
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
MCF7
|
IC50 |
64 nM
Compound: Colchicine
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35084853]
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
MCF7-VP
|
IC50 |
1.57 μM
Compound: Colchicine
|
Cytotoxicity in human MCF7/Vin cells assessed as growth inhibition level after 48 hrs by SRB assay
Cytotoxicity in human MCF7/Vin cells assessed as growth inhibition level after 48 hrs by SRB assay
|
[PMID: 36162138]
|
MDA-MB-231
|
GI50 |
< 0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 25827522]
|
MDA-MB-231
|
IC50 |
0.008 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells by MTS assay
Antiproliferative activity against human MDA-MB-231 cells by MTS assay
|
10.1039/C3MD00077J
|
MDA-MB-231
|
IC50 |
0.023 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
MDA-MB-231
|
IC50 |
0.03 μM
Compound: colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 4 days by microplate assay
Antiproliferative activity against human MDA-MB-231 cells after 4 days by microplate assay
|
[PMID: 17889547]
|
MDA-MB-231
|
IC50 |
0.07 μM
Compound: 1, colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs
|
[PMID: 18503262]
|
MDA-MB-231
|
IC50 |
0.097 μM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35447432]
|
MDA-MB-231
|
IC50 |
0.176 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 36455508]
|
MDA-MB-231
|
IC50 |
0.93 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 32768647]
|
MDA-MB-231
|
GI50 |
1.5 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay
|
[PMID: 30288225]
|
MDA-MB-231
|
IC50 |
|
Anti tumor activity on human breast cancer cell line MDR-negative MDA-MB 231 after 72 hours of treatment
Anti tumor activity on human breast cancer cell line MDR-negative MDA-MB 231 after 72 hours of treatment
|
[PMID: 10602712]
|
MDA-MB-231
|
IC50 |
1.98 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37122544]
|
MDA-MB-231
|
IC50 |
17.5 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
MDA-MB-231
|
IC50 |
2 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
|
[PMID: 30119011]
|
MDA-MB-231
|
IC50 |
|
Antimigratory activity in human MDA-MB-231 cells assessed as inhibition of cell motility after 24 hrs by microscopic analysis
Antimigratory activity in human MDA-MB-231 cells assessed as inhibition of cell motility after 24 hrs by microscopic analysis
|
[PMID: 31838326]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
MDA-MB-231
|
IC50 |
2.94 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
|
[PMID: 32035399]
|
MDA-MB-231
|
IC50 |
20 nM
Compound: colchichine
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
MDA-MB-231
|
IC50 |
22.4 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
MDA-MB-231
|
IC50 |
24.3 nM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-231 cells measured after 72 hrs by western blot
Cytotoxicity against human MDA-MB-231 cells measured after 72 hrs by western blot
|
[PMID: 34378386]
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
MDA-MB-231
|
IC50 |
26 nM
Compound: colchicine
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs
Cytotoxicity against human MDA-MB-231 cells after 72 hrs
|
[PMID: 19530698]
|
MDA-MB-231
|
IC50 |
3.55 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 27608432]
|
MDA-MB-231
|
IC50 |
3.89 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay
Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay
|
[PMID: 29268130]
|
MDA-MB-231
|
IC50 |
37 nM
Compound: colchicine
|
Cytotoxicity against human MDA-MB-231 cells after 96 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 96 hrs by MTT assay
|
[PMID: 23176628]
|
MDA-MB-231
|
IC50 |
38.2 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 28763646]
|
MDA-MB-231
|
IC50 |
|
Antimigratory activity against human MDA-MB-231 cells after 6 hrs by Boyden chamber migration assay
Antimigratory activity against human MDA-MB-231 cells after 6 hrs by Boyden chamber migration assay
|
[PMID: 23524161]
|
MDA-MB-231
|
IC50 |
7.07 μM
Compound: Colchicine
|
Antimigratory activity against Homo sapiens (human) MDA-MB-231 cells after 24 to 48 hr by microscopic analysis
Antimigratory activity against Homo sapiens (human) MDA-MB-231 cells after 24 to 48 hr by microscopic analysis
|
10.1007/s00044-012-0428-9
|
MDA-MB-231
|
IC50 |
77.62 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30197030]
|
MDA-MB-435
|
IC50 |
0.0073 μM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay
|
[PMID: 21536450]
|
MDA-MB-435
|
IC50 |
0.016 μM
Compound: colchicine
|
Antiproliferative activity against human MDA-MB-435 cells by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells by sulforhodamine B assay
|
[PMID: 22611477]
|
MDA-MB-435
|
IC50 |
0.04 μM
Compound: 1, colchicine
|
Antiproliferative activity against human MDA-MB-435 cells after 72 hrs
Antiproliferative activity against human MDA-MB-435 cells after 72 hrs
|
[PMID: 18503262]
|
MDA-MB-435
|
IC50 |
11 nM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 23547728]
|
MDA-MB-435
|
IC50 |
2 μM
Compound: colchicine
|
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by SRB assay
|
[PMID: 18083520]
|
MDA-MB-435
|
IC50 |
658 nM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
MDA-MB-435S
|
IC50 |
0.007 μM
Compound: Colchicine
|
Cytotoxicity against human MDA-MB-435S cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human MDA-MB-435S cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25091926]
|
MDA-MB-453
|
IC50 |
5.8 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-453 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human MDA-MB-453 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
MDA-MB-468
|
IC50 |
0.06 μM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-468 cells by SRB assay
Antiproliferative activity against human MDA-MB-468 cells by SRB assay
|
[PMID: 28988750]
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human MDA-MB-468 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
MDA-MB-468
|
IC50 |
9.9 nM
Compound: Colchicine
|
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
|
[PMID: 26132075]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
MES-SA
|
IC50 |
|
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
Cytotoxicity against human MESSA cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
|
[PMID: 25025991]
|
MES-SA
|
IC50 |
15 nM
Compound: Colchicine
|
Antiproliferative activity against human MES-SA cells after 72 hrs by resazurin assay
Antiproliferative activity against human MES-SA cells after 72 hrs by resazurin assay
|
[PMID: 26602281]
|
MES-SA
|
IC50 |
6.3 nM
Compound: colchicine
|
Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
|
[PMID: 17286393]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
|
[PMID: 26132075]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by Celltiter-Glo luminescent assay
|
[PMID: 23214452]
|
MES-SA/Dx5
|
IC50 |
|
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
Cytotoxicity against human MESSA/DX5 cells assessed as growth inhibition after 72 hrs by CellTitre-Glo assay
|
[PMID: 25025991]
|
MES-SA/Dx5
|
IC50 |
63 nM
Compound: colchicine
|
Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
|
[PMID: 17286393]
|
MES-SA/Dx5
|
IC50 |
757 nM
Compound: Colchicine
|
Antiproliferative activity against multidrug-resistant human MES-SA/Dx5 cells assessed as reduction in cell viability incubated for 72 hrs by prestoblue dye based assay
Antiproliferative activity against multidrug-resistant human MES-SA/Dx5 cells assessed as reduction in cell viability incubated for 72 hrs by prestoblue dye based assay
|
[PMID: 33618157]
|
MGC-803
|
IC50 |
0.062 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35834904]
|
MGC-803
|
IC50 |
0.062 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 35605363]
|
MGC-803
|
IC50 |
0.09 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34971875]
|
MGC-803
|
IC50 |
0.107 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32682200]
|
MGC-803
|
IC50 |
0.177 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
|
[PMID: 30075402]
|
MGC-803
|
IC50 |
0.27 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC803 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MGC803 cells measured after 48 hrs by MTT assay
|
[PMID: 30690300]
|
MGC-803
|
IC50 |
1.07 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay
|
[PMID: 34022412]
|
MGC-803
|
IC50 |
1.07 μM
Compound: Colchicine
|
Antiproliferative activity against human MGC-803 cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human MGC-803 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 33965530]
|
MHCC97H
|
IC50 |
0.11 μM
Compound: Colchicine
|
Cytotoxicity against human MHCC97H cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MHCC97H cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against human Mia PaCa-2 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human Mia PaCa-2 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
MIA PaCa-2
|
IC50 |
|
Cytotoxic activity in human MIAPaCa2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxic activity in human MIAPaCa2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 29028531]
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against 2D culture of human MIAPaCa2 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human MIAPaCa2 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
MIA PaCa-2
|
IC50 |
25 nM
Compound: colchichine
|
Cytotoxicity against human MIAPaCa2 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MIAPaCa2 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
MIA PaCa-2
|
IC50 |
6.1 nM
Compound: Colchicine
|
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
MKN-45
|
IC50 |
0.002 μM
Compound: Colchicine
|
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
MKN-45
|
IC50 |
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
Antiproliferative activity against human MKN45 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
|
10.1039/C0MD00052C
|
MKN-45
|
IC50 |
|
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
|
[PMID: 24106982]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
MKN-45
|
IC50 |
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19053773]
|
MKN-45
|
IC50 |
13 nM
Compound: colchichine
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue dye assay
|
[PMID: 17685504]
|
MKN-45
|
IC50 |
14.9 nM
Compound: Colchicine
|
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 26160020]
|
MKN-45
|
IC50 |
14.9 nM
Compound: colchicine
|
Cytotoxicity against human MKN45 cells after 72 hrs by methylene blue assay
Cytotoxicity against human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 24657567]
|
MKN-45
|
IC50 |
15 nM
Compound: Colchicine
|
Cytotoxicity against human MKN45 cell line by methylene blue dye assay
Cytotoxicity against human MKN45 cell line by methylene blue dye assay
|
[PMID: 17154496]
|
MKN-45
|
IC50 |
|
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue assay
Growth inhibition of human MKN45 cells after 72 hrs by methylene blue assay
|
[PMID: 22060033]
|
MOLM-13
|
IC50 |
4.71 nM
Compound: Colchicine
|
Antiproliferative activity against human MOLM-13 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MOLM-13 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
MRC5
|
IC50 |
0.09 μM
Compound: Colchicine
|
Antiproliferative activity against human MRC5 cells by SRB assay
Antiproliferative activity against human MRC5 cells by SRB assay
|
[PMID: 28988750]
|
MRC5
|
IC50 |
6.2 μM
Compound: Colchicine
|
Antiproliferative activity against human MRC5 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MRC5 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30878833]
|
MV4-11
|
IC50 |
1.58 nM
Compound: Colchicine
|
Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
NCI/ADR-RES
|
IC50 |
1113 nM
Compound: Colchicine
|
Anticancer activity against P-gp overexpressing human NCI/ADR-RES cells after 96 hrs by SRB assay
Anticancer activity against P-gp overexpressing human NCI/ADR-RES cells after 96 hrs by SRB assay
|
[PMID: 21557538]
|
NCI/ADR-RES
|
IC50 |
3.12 μM
Compound: Colchicine
|
Cytotoxicity against human MCF7/ADR cells by MTT assay
Cytotoxicity against human MCF7/ADR cells by MTT assay
|
[PMID: 23425970]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against Pgp overexpressing human NCI-ADR-RES cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against Pgp overexpressing human NCI-ADR-RES cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human NCI/ADR-RES cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against P-gp overexpressing human MCF7/ADR cells assessed as reduction in cell growth after 24 hrs by MTT assay
Cytotoxicity against P-gp overexpressing human MCF7/ADR cells assessed as reduction in cell growth after 24 hrs by MTT assay
|
[PMID: 27213819]
|
NCI-H1299
|
IC50 |
0.004 μM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H1299 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H1299 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
NCI-H1299
|
EC50 |
0.034 μM
Compound: colchicine
|
Induction of apoptosis in human H1299 cells assessed as caspase activation after 24 hrs
Induction of apoptosis in human H1299 cells assessed as caspase activation after 24 hrs
|
[PMID: 15566300]
|
NCI-H1299
|
EC50 |
0.05 μM
Compound: colchicine
|
Induction of apoptosis in human H1299 cells assessed as caspase activation after 48 hrs by HTS assay
Induction of apoptosis in human H1299 cells assessed as caspase activation after 48 hrs by HTS assay
|
[PMID: 19464890]
|
NCI-H1299
|
EC50 |
0.05 μM
Compound: Colchicine
|
Induction of apoptosis in human H1299 cells assessed as caspase activation after 48 hrs
Induction of apoptosis in human H1299 cells assessed as caspase activation after 48 hrs
|
[PMID: 19500976]
|
NCI-H1299
|
GI50 |
0.063 μM
Compound: Colchicine
|
Growth inhibition of human H1299 cells after 48 hrs
Growth inhibition of human H1299 cells after 48 hrs
|
[PMID: 19500976]
|
NCI-H1299
|
IC50 |
30 nM
Compound: colchicine
|
Cytotoxicity against human H1299 cells after 72 hrs
Cytotoxicity against human H1299 cells after 72 hrs
|
[PMID: 19530698]
|
NCI-H1437
|
IC50 |
0.002 μM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H1437 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H1437 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
NCI-H157
|
IC50 |
|
Cytotoxicity in human NCI-H157 cells assessed as reduction in cell viability after 4 days under dark condition by MTT assay
Cytotoxicity in human NCI-H157 cells assessed as reduction in cell viability after 4 days under dark condition by MTT assay
|
[PMID: 29172077]
|
NCI-H23
|
IC50 |
|
Cell cycle arrest in human NCI-H23 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human NCI-H23 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
NCI-H358
|
IC50 |
0.02 μM
Compound: Colchicine
|
Cytotoxicity against human NCI-H358 cells by MTT assay
Cytotoxicity against human NCI-H358 cells by MTT assay
|
[PMID: 23425970]
|
NCI-H358
|
IC50 |
4 nM
Compound: colchicine
|
Antiproliferative activity against human NCI-H358 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H358 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
NCI-H460
|
IC50 |
0.01 μM
Compound: colchicine
|
Antiproliferative activity against human NCI-H460 cells by XTT assay
Antiproliferative activity against human NCI-H460 cells by XTT assay
|
[PMID: 19220018]
|
NCI-H460
|
IC50 |
0.021 μM
Compound: Colchicine
|
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition by MTT assay
|
[PMID: 25091926]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
NCI-H460
|
IC50 |
0.022 μM
Compound: Colchicine
|
Cytotoxicity against human H460 cells after 72 hrs by MTT assay
Cytotoxicity against human H460 cells after 72 hrs by MTT assay
|
[PMID: 23932339]
|
NCI-H460
|
IC50 |
0.027 μM
Compound: colchicine
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
NCI-H460
|
EC50 |
|
Cytotoxicity against human H460 after 3 days by SRB assay
Cytotoxicity against human H460 after 3 days by SRB assay
|
[PMID: 15730238]
|
NCI-H460
|
IC50 |
0.054 μM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells after 68 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 68 hrs by MTT assay
|
[PMID: 32243160]
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by XTT assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by XTT assay
|
[PMID: 21705223]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by XTT assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by XTT assay
|
[PMID: 20537765]
|
NCI-H460
|
IC50 |
0.07 μM
Compound: colchicine
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by XTT assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by XTT assay
|
[PMID: 17973361]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against NCI-H460 cells by XTT assay after 48 hrs
Antiproliferative activity against NCI-H460 cells by XTT assay after 48 hrs
|
[PMID: 17181164]
|
NCI-H460
|
IC50 |
0.07 μM
Compound: 2 (Colchicine)
|
Cytotoxic activity against cellular metabolic activity of Lung NCI-H460 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
Cytotoxic activity against cellular metabolic activity of Lung NCI-H460 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
|
[PMID: 12852768]
|
NCI-H460
|
IC50 |
0.71 μM
Compound: Colchicine
|
Growth inhibition of human NCI-H460 cells after 72 hrs by MTT assay
Growth inhibition of human NCI-H460 cells after 72 hrs by MTT assay
|
[PMID: 23747810]
|
NCI-H460
|
IC50 |
12 nM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35084853]
|
NCI-H460
|
IC50 |
18 nM
Compound: Colchicine
|
Cytotoxicity against human H460 cells after 72 hrs by methylene blue dye assay
Cytotoxicity against human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19586033]
|
NCI-H460
|
IC50 |
|
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 19053773]
|
NCI-H460
|
IC50 |
19 nM
Compound: colchichine
|
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 17685504]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
Antiproliferative activity against human H460 cells assessed as inhibition of cell growth after 72 hrs by methylene blue dye assay
|
10.1039/C0MD00052C
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human H460 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
Cytotoxicity against human H460 cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay
|
[PMID: 24106982]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue assay
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue assay
|
[PMID: 21641700]
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue dye assay
Antiproliferative activity against human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 20148562]
|
NCI-H460
|
IC50 |
|
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
Growth inhibition of human H460 cells after 72 hrs by methylene blue dye assay
|
[PMID: 18588280]
|
NCI-H460
|
IC50 |
27 μM
Compound: Colchicine
|
Cytotoxicity against human H460 cells by MTT assay
Cytotoxicity against human H460 cells by MTT assay
|
[PMID: 23425970]
|
NCI-H460
|
IC50 |
35.8 nM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H460 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
NCI-H460
|
IC50 |
|
Growth inhibition of human NCI-H460 cells incubated for 48 hrs by MTT assay
Growth inhibition of human NCI-H460 cells incubated for 48 hrs by MTT assay
|
[PMID: 27172319]
|
NCI-H460
|
IC50 |
50.6 nM
Compound: Colchicine
|
Antiproliferative activity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
NCI-H520
|
GI50 |
< 0.05 μM
Compound: colchicine
|
Compound was evaluated for growth inhibition against NCI-H520 cells using cellular assay
Compound was evaluated for growth inhibition against NCI-H520 cells using cellular assay
|
[PMID: 9871709]
|
NCI-H522
|
IC50 |
|
Cell cycle arrest in human NCI-H522 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human NCI-H522 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
NCI-N87
|
IC50 |
|
Cytotoxicity against human NCI-N87 cells assessed as cell viability after 4 days by MTS assay
Cytotoxicity against human NCI-N87 cells assessed as cell viability after 4 days by MTS assay
|
[PMID: 24210503]
|
NIH3T3
|
IC50 |
|
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
|
[PMID: 23524161]
|
NIH3T3
|
IC50 |
|
Cytotoxicity against mouse NIH/3T3 cells harboring MDR G185 after 48 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells harboring MDR G185 after 48 hrs by MTT assay
|
[PMID: 30448418]
|
NIH3T3
|
IC50 |
|
Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by MTT assay
Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by MTT assay
|
[PMID: 30448418]
|
NUGC-3
|
IC50 |
0.01 μM
Compound: Colchicine
|
Anticancer activity against human NUGC3 cells after 72 hrs by MTS/PMS assay
Anticancer activity against human NUGC3 cells after 72 hrs by MTS/PMS assay
|
[PMID: 20170097]
|
OVCAR-8
|
IC50 |
17 nM
Compound: Colchicine
|
Anticancer activity against human OVCAR8 cells after 96 hrs by SRB assay
Anticancer activity against human OVCAR8 cells after 96 hrs by SRB assay
|
[PMID: 21557538]
|
OVCAR-8
|
IC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 26132075]
|
OVCAR-8
|
IC50 |
|
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 96 hrs by Giemsa staining-based light microscopy
|
[PMID: 25025991]
|
P388
|
IC50 |
|
Antiproliferative activity against mouse P388 cells incubated for 72 hrs by Coulter counter method
Antiproliferative activity against mouse P388 cells incubated for 72 hrs by Coulter counter method
|
[PMID: 32432867]
|
P388
|
IC50 |
24 nM
Compound: Colchicine
|
Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
|
[PMID: 2778449]
|
P388D1
|
IC50 |
|
Antiproliferative activity against human P388D1 after 48 hrs by SRB assay
Antiproliferative activity against human P388D1 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
P388D1
|
IC50 |
|
Antiproliferative activity against mouse P388D1 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against mouse P388D1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
PANC-1
|
GI50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human PANC1 cells after 48 hrs by SRB assay
Antiproliferative activity against human PANC1 cells after 48 hrs by SRB assay
|
[PMID: 25827522]
|
PANC-1
|
IC50 |
0.021 μM
Compound: Colchicine
|
Cytotoxicity against human PANC1 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human PANC1 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
PANC-1
|
IC50 |
|
Antiproliferative activity against human PANC-1 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human PANC-1 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
PANC-1
|
IC50 |
|
Cytotoxicity against 2D culture of human PANC1 cells measured after 72 hrs by MTT assay
Cytotoxicity against 2D culture of human PANC1 cells measured after 72 hrs by MTT assay
|
[PMID: 27912174]
|
PBMC
|
IC50 |
|
Cytotoxicity against human PBMC cells after 24 hrs by MTT assay
Cytotoxicity against human PBMC cells after 24 hrs by MTT assay
|
[PMID: 23524161]
|
PBMC
|
IC50 |
> 10000 nM
Compound: Colchicine
|
Antiproliferative activity against human PBMC after 72 hrs by MTS assay
Antiproliferative activity against human PBMC after 72 hrs by MTS assay
|
[PMID: 30099258]
|
PC-3
|
GI50 |
< 0.05 μM
Compound: colchicine
|
Compound was evaluated for growth inhibition against PC-3 cells using cellular assay
Compound was evaluated for growth inhibition against PC-3 cells using cellular assay
|
[PMID: 9871709]
|
PC-3
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay
|
[PMID: 22608389]
|
PC-3
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells after 96 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 96 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
PC-3
|
IC50 |
0.011 μM
Compound: colchicine
|
Cytotoxicity against human PC3 cells after 48 hrs by SRB assay
Cytotoxicity against human PC3 cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
PC-3
|
IC50 |
|
Growth inhibition of human PC3 cells incubated for 72 hrs by MTT assay
Growth inhibition of human PC3 cells incubated for 72 hrs by MTT assay
|
[PMID: 27172319]
|
PC-3
|
IC50 |
0.018 μM
Compound: colchicine
|
Cytotoxicity against human PC3 cells after 3 days by MTT assay
Cytotoxicity against human PC3 cells after 3 days by MTT assay
|
[PMID: 17275318]
|
PC-3
|
IC50 |
0.03 μM
Compound: Colchicine
|
Cytotoxicity against human PC-3 cells treated for 72 hrs by MTT assay
Cytotoxicity against human PC-3 cells treated for 72 hrs by MTT assay
|
[PMID: 35344904]
|
PC-3
|
IC50 |
|
Cell cycle arrest in human PC3 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human PC3 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
PC-3
|
IC50 |
0.04 μM
Compound: Colchicine
|
Cytotoxicity against human PC3 cells by MTT assay
Cytotoxicity against human PC3 cells by MTT assay
|
[PMID: 23425970]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT assay
|
[PMID: 32432867]
|
PC-3
|
IC50 |
0.074 μM
Compound: Colchicine
|
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 23602523]
|
PC-3
|
IC50 |
0.13 μM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 30075402]
|
PC-3
|
IC50 |
0.338 μM
Compound: Colchicine
|
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32682200]
|
PC-3
|
IC50 |
0.59 μM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
|
[PMID: 30690300]
|
PC-3
|
IC50 |
11 nM
Compound: Colchicine
|
Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
PC-3
|
IC50 |
11.5 nM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
|
[PMID: 22783954]
|
PC-3
|
IC50 |
19 nM
Compound: Colchicine
|
Antiproliferative activity against human PC3 cells measured after 72 hrs by MTS assay
Antiproliferative activity against human PC3 cells measured after 72 hrs by MTS assay
|
[PMID: 31860298]
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells after 72 hrs by crystal violet staining
Cytotoxicity against human PC3 cells after 72 hrs by crystal violet staining
|
[PMID: 20529690]
|
PC-3
|
IC50 |
8 nM
Compound: Colchicine
|
Cytotoxicity against human PC3 cells after 72 hrs by MTS assay
Cytotoxicity against human PC3 cells after 72 hrs by MTS assay
|
[PMID: 29406710]
|
PPC-1
|
IC50 |
0.02 μM
Compound: colchicine
|
Cytotoxicity against human PPC1 cells after 48 hrs by SRB assay
Cytotoxicity against human PPC1 cells after 48 hrs by SRB assay
|
[PMID: 19243174]
|
PPC-1
|
IC50 |
0.02 μM
Compound: Colchicine
|
Antiproliferative activity against human PPC1 cells after 96 hrs by sulforhodamine B assay
Antiproliferative activity against human PPC1 cells after 96 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
PPC-1
|
IC50 |
20 nM
Compound: Colchicine
|
Cytotoxicity against human PPC1 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human PPC1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20919720]
|
Raji
|
EC50 |
0.014 μM
Compound: Colchicine
|
Cytotoxicity against human Raji cells after 48 hrs by luminescence cell viability assay
Cytotoxicity against human Raji cells after 48 hrs by luminescence cell viability assay
|
[PMID: 18684625]
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Raji cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
Raji
|
IC50 |
18 nM
Compound: Colchicine
|
Antiproliferative activity against human Raji cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Antiproliferative activity against human Raji cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 35084853]
|
Ramos
|
IC50 |
2.13 nM
Compound: Colchicine
|
Antiproliferative activity against human Ramos cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human Ramos cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
REH
|
IC50 |
|
Cytotoxicity against human REH cells after 48 hrs by MTT assay
Cytotoxicity against human REH cells after 48 hrs by MTT assay
|
[PMID: 23524161]
|
RKO
|
IC50 |
|
Antiproliferative activity against human RKO cells expressing p27Kip1 after 48 hrs by XTT assay
Antiproliferative activity against human RKO cells expressing p27Kip1 after 48 hrs by XTT assay
|
[PMID: 20537765]
|
RKO
|
IC50 |
|
Antiproliferative activity against RKO cells with ectopic-induced p27kip1-expression by XTT assay after 48 hrs
Antiproliferative activity against RKO cells with ectopic-induced p27kip1-expression by XTT assay after 48 hrs
|
[PMID: 17181164]
|
RKO
|
IC50 |
> 14 μM
Compound: colchicine
|
Cytotoxicity against human RKO cells with ectopic-inducible expression of p27kip1 after 48 hrs by XTT assay
Cytotoxicity against human RKO cells with ectopic-inducible expression of p27kip1 after 48 hrs by XTT assay
|
[PMID: 17973361]
|
RKO
|
IC50 |
> 3 μM
Compound: colchicine
|
Antiproliferative activity against human RKO cells containing ecdysone-inducible expression vector of p27kipl by XTT assay
Antiproliferative activity against human RKO cells containing ecdysone-inducible expression vector of p27kipl by XTT assay
|
[PMID: 19220018]
|
RKO
|
IC50 |
> 5 μM
Compound: Colchicine
|
Cytotoxicity against cell cycle arrested RKOp27 cells after 72 hrs by alamar blue assay
Cytotoxicity against cell cycle arrested RKOp27 cells after 72 hrs by alamar blue assay
|
[PMID: 16970401]
|
RKO
|
IC50 |
0.01 μM
Compound: colchicine
|
Antiproliferative activity against human RKO cells by XTT assay
Antiproliferative activity against human RKO cells by XTT assay
|
[PMID: 19220018]
|
RKO
|
IC50 |
0.016 μM
Compound: Colchicine
|
Cytotoxicity against proliferating RKOp27 cells after 72 hrs by Alamar Blue assay
Cytotoxicity against proliferating RKOp27 cells after 72 hrs by Alamar Blue assay
|
[PMID: 16970401]
|
RKO
|
IC50 |
|
Antiproliferative activity against human RKO cells after 48 hrs by XTT assay
Antiproliferative activity against human RKO cells after 48 hrs by XTT assay
|
[PMID: 20537765]
|
RKO
|
IC50 |
0.02 μM
Compound: colchicine
|
Cytotoxicity against human RKO cells after 48 hrs by XTT assay
Cytotoxicity against human RKO cells after 48 hrs by XTT assay
|
[PMID: 17973361]
|
RKO
|
IC50 |
|
Antiproliferative activity against RKO cells by XTT assay after 48 hrs
Antiproliferative activity against RKO cells by XTT assay after 48 hrs
|
[PMID: 17181164]
|
RKO
|
IC50 |
0.043 μM
Compound: Colchicine
|
Antiproliferative activity against human RKO cells after 48 hrs by MTT assay
Antiproliferative activity against human RKO cells after 48 hrs by MTT assay
|
[PMID: 30093295]
|
RL
|
IC50 |
4.4 nM
Compound: Colchicine
|
Antiproliferative activity against human RL cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human RL cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33618157]
|
RPMI-7951
|
IC50 |
13.8 nM
Compound: Colchicine
|
Antiproliferative activity against human RPMI-7951 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
Antiproliferative activity against human RPMI-7951 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTS assay
|
[PMID: 34406768]
|
RPMI-7951
|
IC50 |
6.6 nM
Compound: Colchicine
|
Cytotoxicity against human RPMI7951 cells after 72 hrs by MTS assay
Cytotoxicity against human RPMI7951 cells after 72 hrs by MTS assay
|
[PMID: 29406710]
|
SF-268
|
IC50 |
0.01 μM
Compound: colchicine
|
Antiproliferative activity against human SF268 cells by XTT assay
Antiproliferative activity against human SF268 cells by XTT assay
|
[PMID: 19220018]
|
SF-268
|
EC50 |
|
Cytotoxicity against human SF-268 after 3 days by SRB assay
Cytotoxicity against human SF-268 after 3 days by SRB assay
|
[PMID: 15730238]
|
SF-268
|
IC50 |
|
Cytotoxicity against human SF268 cells after 48 hrs by XTT assay
Cytotoxicity against human SF268 cells after 48 hrs by XTT assay
|
[PMID: 21705223]
|
SF-268
|
IC50 |
|
Antiproliferative activity against human SF268 cells after 48 hrs by XTT assay
Antiproliferative activity against human SF268 cells after 48 hrs by XTT assay
|
[PMID: 20537765]
|
SF-268
|
IC50 |
0.05 μM
Compound: colchicine
|
Cytotoxicity against human SF268 cells after 48 hrs by XTT assay
Cytotoxicity against human SF268 cells after 48 hrs by XTT assay
|
[PMID: 17973361]
|
SF-268
|
IC50 |
|
Antiproliferative activity against SF268 cells by XTT assay after 48 hrs
Antiproliferative activity against SF268 cells by XTT assay after 48 hrs
|
[PMID: 17181164]
|
SF-268
|
IC50 |
0.05 μM
Compound: 2 (Colchicine)
|
Cytotoxic activity against cellular metabolic activity of Glioma SF-268 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
Cytotoxic activity against cellular metabolic activity of Glioma SF-268 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
|
[PMID: 12852768]
|
SGC-7901
|
IC50 |
0.007 μM
Compound: Colchicine
|
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34571171]
|
SGC-7901
|
IC50 |
0.05 μM
Compound: Colchicine
|
Cytotoxicity against human SGC7901 cells after 48 hrs
Cytotoxicity against human SGC7901 cells after 48 hrs
|
[PMID: 23022053]
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
|
[PMID: 30245397]
|
SH-SY5Y
|
GI50 |
0.04 μM
Compound: Colchicine
|
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
|
[PMID: 28763647]
|
SH-SY5Y
|
IC50 |
|
Antiproliferative activity against human SH-SY5Y cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human SH-SY5Y cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 35694693]
|
SiHa
|
IC50 |
|
Antiproliferation activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
Antiproliferation activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay
|
[PMID: 35339837]
|
SJSA-1
|
IC50 |
0.008 μM
Compound: Colchicine
|
Cytotoxicity against human SJSA1 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SJSA1 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
SK-BR-3
|
ED50 |
|
Cytotoxicity against human SKBR3 cells after 2 days
Cytotoxicity against human SKBR3 cells after 2 days
|
[PMID: 20542428]
|
SK-BR-3
|
IC50 |
0.0064 μM
Compound: Colchicine
|
Growth inhibition of human SKBR3 cells after 48 hrs by MTT assay
Growth inhibition of human SKBR3 cells after 48 hrs by MTT assay
|
[PMID: 22850214]
|
SK-BR-3
|
IC50 |
0.04 μM
Compound: Colchicine
|
Cytotoxicity against human SK-BR-3 cells treated for 72 hrs by MTT assay
Cytotoxicity against human SK-BR-3 cells treated for 72 hrs by MTT assay
|
[PMID: 35344904]
|
SK-HEP1
|
IC50 |
0.17 μM
Compound: Colchicine
|
Cytotoxicity against human SKHEP1 cells by MTT assay
Cytotoxicity against human SKHEP1 cells by MTT assay
|
[PMID: 23425970]
|
SK-MEL-2
|
ED50 |
0.008 μg/mL
Compound: colchicine
|
The compound was tested for the cytotoxicity for the cell lines of human melanoma cancer (SKMEL-2) using SRB assay.
The compound was tested for the cytotoxicity for the cell lines of human melanoma cancer (SKMEL-2) using SRB assay.
|
[PMID: 9544215]
|
SK-MEL-2
|
IC50 |
6 nM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human SK-MEL-2 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
Antiproliferative activity against human SK-MEL-2 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
|
[PMID: 31655432]
|
SK-MES-1
|
IC50 |
|
Cytotoxicity against human SKMES1 cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
Cytotoxicity against human SKMES1 cells after 48 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 26985296]
|
SK-OV-3
|
IC50 |
0.01 μM
Compound: colchicine
|
Antiproliferative activity against human SKOV3 cells by XTT assay
Antiproliferative activity against human SKOV3 cells by XTT assay
|
[PMID: 19220018]
|
SK-OV-3
|
IC50 |
0.02 μM
Compound: Colchicine
|
In vitro inhibitory activity against SK-OV-3 cells using XTT proliferation assay.
In vitro inhibitory activity against SK-OV-3 cells using XTT proliferation assay.
|
[PMID: 11741473]
|
SK-OV-3
|
IC50 |
0.029 μM
Compound: colchicine
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
SK-OV-3
|
IC50 |
0.05 μM
Compound: Colchicine
|
Antiproliferative activity against human SKOV3 cells by SRB assay
Antiproliferative activity against human SKOV3 cells by SRB assay
|
[PMID: 28988750]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells after 48 hrs by XTT assay
Cytotoxicity against human SKOV3 cells after 48 hrs by XTT assay
|
[PMID: 21705223]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by XTT assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by XTT assay
|
[PMID: 20537765]
|
SK-OV-3
|
IC50 |
0.05 μM
Compound: colchicine
|
Cytotoxicity against human SKOV3 cells after 48 hrs by XTT assay
Cytotoxicity against human SKOV3 cells after 48 hrs by XTT assay
|
[PMID: 17973361]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against SKOV3 cells by XTT assay after 48 hrs
Antiproliferative activity against SKOV3 cells by XTT assay after 48 hrs
|
[PMID: 17181164]
|
SK-OV-3
|
IC50 |
0.05 μM
Compound: 2 (Colchicine)
|
Cytotoxic activity against cellular metabolic activity of Ovary SKOV3 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
Cytotoxic activity against cellular metabolic activity of Ovary SKOV3 tumor cell line using XTT proliferation assay after incubation with the compound for 48 h
|
[PMID: 12852768]
|
SK-OV-3
|
IC50 |
0.12 μM
Compound: Colchicine
|
Cytotoxicity against human SKOV3 cells by MTT assay
Cytotoxicity against human SKOV3 cells by MTT assay
|
[PMID: 23425970]
|
SK-OV-3
|
IC50 |
18 nM
Compound: 1; (-)-Colchicine
|
Antiproliferative activity against human SKOV3 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
Antiproliferative activity against human SKOV3 cells assessed as reduction in cell viability incubated for 24 hrs by SRB assay
|
[PMID: 31655432]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human SKOV3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 after 48 hrs by SRB assay
Antiproliferative activity against human SKOV3 after 48 hrs by SRB assay
|
[PMID: 21920638]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21604746]
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against arrested non-proliferative human SKOV3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against arrested non-proliferative human SKOV3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 30429975]
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 24 hrs by MTT assay
Antiproliferative activity against human SKOV3 cells after 24 hrs by MTT assay
|
[PMID: 27213819]
|
SK-OV-3
|
IC50 |
71.2 nM
Compound: Colchicine
|
Antiproliferative activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 21480626]
|
SNU-16
|
IC50 |
0.005 μM
Compound: Colchicine
|
Cytotoxicity against human SNU16 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SNU16 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
SNU-398
|
EC50 |
0.004 μM
Compound: colchicine
|
Induction of apoptosis in human SNU398 cells assessed as caspase activation after 24 hrs by HTS assay
Induction of apoptosis in human SNU398 cells assessed as caspase activation after 24 hrs by HTS assay
|
[PMID: 18197614]
|
SNU-423
|
IC50 |
25 nM
Compound: colchichine
|
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
|
[PMID: 19117761]
|
SNU-5
|
IC50 |
0.034 μM
Compound: Colchicine
|
Cytotoxicity against human SNU5 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SNU5 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
Splenocyte
|
IC50 |
|
Immunosuppressant activity in mouse splenocytes by mixed-leukocyte reaction assay
Immunosuppressant activity in mouse splenocytes by mixed-leukocyte reaction assay
|
[PMID: 23017885]
|
SW1990
|
IC50 |
0.01 μM
Compound: Colchicine
|
Antiproliferative activity against human SW1990 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human SW1990 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36511661]
|
SW480
|
IC50 |
0.03 μM
Compound: colchicine
|
Antiproliferative activity against human SW480 cells after 48 hrs by alamar blue assay
Antiproliferative activity against human SW480 cells after 48 hrs by alamar blue assay
|
[PMID: 21563750]
|
SW480
|
IC50 |
|
Antiproliferative activity against human SW480 cells after 48 hrs by SRB method
Antiproliferative activity against human SW480 cells after 48 hrs by SRB method
|
[PMID: 25061803]
|
SW480
|
IC50 |
14.9 nM
Compound: Colchicine
|
Antiproliferative activity against human SW480 cells after 72 hrs by MTS assay
Antiproliferative activity against human SW480 cells after 72 hrs by MTS assay
|
[PMID: 30099258]
|
SW-620
|
IC50 |
0.005 μM
Compound: Colchicine
|
Cytotoxicity against human SW620 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human SW620 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25805446]
|
SW-620
|
IC50 |
|
Cell cycle arrest in human SW620 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human SW620 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW-620 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human SW-620 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32827941]
|
SW780
|
IC50 |
6.7 nM
Compound: colchicine
|
Cytotoxicity against human SW780 cells after 96 hrs by MTT assay
Cytotoxicity against human SW780 cells after 96 hrs by MTT assay
|
[PMID: 23176628]
|
T47D
|
GI50 |
0.007 μM
Compound: Colchicine
|
Growth inhibition of human T47D cells after 48 hrs
Growth inhibition of human T47D cells after 48 hrs
|
[PMID: 19282188]
|
T47D
|
GI50 |
0.007 μM
Compound: colchicine
|
Growth inhibition of human T47D cells after 48 hrs
Growth inhibition of human T47D cells after 48 hrs
|
[PMID: 18197614]
|
T47D
|
EC50 |
0.009 μM
Compound: colchicine
|
Induction of apoptosis in human T47D cells assessed as caspase activation after 24 hrs by HTS assay
Induction of apoptosis in human T47D cells assessed as caspase activation after 24 hrs by HTS assay
|
[PMID: 18197614]
|
T47D
|
EC50 |
0.009 μM
Compound: colchicine
|
Induction of apoptosis in human T47D cells assessed as caspase activation after 48 hrs by HTS assay
Induction of apoptosis in human T47D cells assessed as caspase activation after 48 hrs by HTS assay
|
[PMID: 19464890]
|
T47D
|
EC50 |
0.009 μM
Compound: colchicine
|
Induction of apoptosis in human T47D cells assessed as caspase 3 activation after 24 hrs
Induction of apoptosis in human T47D cells assessed as caspase 3 activation after 24 hrs
|
[PMID: 18651728]
|
T47D
|
EC50 |
0.014 μM
Compound: colchicine
|
Induction of apoptosis in human T47D cells assessed as caspase activation after 24 hrs
Induction of apoptosis in human T47D cells assessed as caspase activation after 24 hrs
|
[PMID: 15566300]
|
T47D
|
EC50 |
0.014 μM
Compound: Colchicine
|
Induction of apoptosis in human T47D cells assessed as caspase activation after 48 hrs
Induction of apoptosis in human T47D cells assessed as caspase activation after 48 hrs
|
[PMID: 19500976]
|
T47D
|
GI50 |
0.14 μM
Compound: Colchicine
|
Growth inhibition of human T47D cells after 48 hrs
Growth inhibition of human T47D cells after 48 hrs
|
[PMID: 19500976]
|
T-cell
|
IC50 |
|
Immunosuppressive activity in concanavalin A-activated T cell assessed as inhibition of lymphoproliferation after 3 days by beta-scintillation counting
Immunosuppressive activity in concanavalin A-activated T cell assessed as inhibition of lymphoproliferation after 3 days by beta-scintillation counting
|
[PMID: 19502058]
|
TERT-RPE1
|
CC50 |
0.1 μM
Compound: Colchicine
|
Cytotoxicity against hTERT-RPE1 cells assessed as reduction in cell viability after 72 hrs by sulforhodamine B assay
Cytotoxicity against hTERT-RPE1 cells assessed as reduction in cell viability after 72 hrs by sulforhodamine B assay
|
[PMID: 30288225]
|
THP-1
|
IC50 |
2.49 nM
Compound: Colchicine
|
Antiproliferative activity against human THP-1 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human THP-1 cells incubated for 72 hrs by MTT assay
|
[PMID: 34648295]
|
THP-1
|
IC50 |
|
Cytotoxicity against human THP1 cells after 24 hrs by Celltiter-Glo luminescent cell viability assay
Cytotoxicity against human THP1 cells after 24 hrs by Celltiter-Glo luminescent cell viability assay
|
[PMID: 26985296]
|
U-251
|
IC50 |
|
Antiproliferative activity against human U-251 cells after 48 hrs by MTT assay
Antiproliferative activity against human U-251 cells after 48 hrs by MTT assay
|
[PMID: 34311158]
|
U-251
|
IC50 |
20 nM
Compound: colchicine
|
Antiproliferative activity against human U251 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Antiproliferative activity against human U251 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 25208345]
|
U-266
|
IC50 |
|
Cell cycle arrest in human U266 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
Cell cycle arrest in human U266 cells assessed as accumulation at G2/M phase after 24 hrs using propidium iodide staining by FACS analysis
|
[PMID: 21126027]
|
U-937
|
IC50 |
0.008 μM
Compound: Colchicine
|
Antiproliferative activity against human U937 cells by sulforhodamine B assay
Antiproliferative activity against human U937 cells by sulforhodamine B assay
|
[PMID: 20334421]
|
U-937
|
IC50 |
0.1 μg/mL
Compound: Colchicine
|
Cytotoxicity against human U937 cells after 48 hrs by MTT assay
Cytotoxicity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 15165134]
|
Vero
|
EC50 |
0.27 μM
Compound: Colchicine
|
Cell cycle arrest in african green monkey Vero cells assessed as accumulation at G2/M phase after 18 hrs by flow cytometry using propidium iodide staining
Cell cycle arrest in african green monkey Vero cells assessed as accumulation at G2/M phase after 18 hrs by flow cytometry using propidium iodide staining
|
[PMID: 18684625]
|
Vero
|
EC50 |
0.39 μM
Compound: Colchicine
|
Induction of apoptosis in african green monkey Vero cells assessed as caspase 3/7 activity after 18 hrs by flow cytometry using propidium iodide staining
Induction of apoptosis in african green monkey Vero cells assessed as caspase 3/7 activity after 18 hrs by flow cytometry using propidium iodide staining
|
[PMID: 18684625]
|
Vero
|
EC50 |
0.53 μM
Compound: Colchicine
|
Cytotoxicity against african green monkey Vero cells after 48 hrs by luminescence cell viability assay
Cytotoxicity against african green monkey Vero cells after 48 hrs by luminescence cell viability assay
|
[PMID: 18684625]
|
WI-38
|
EC50 |
0.022 μM
Compound: Colchicine
|
Antiviral activity against BKV Gardner ATCC VR837 infected in human WI38 cells assessed as reduction in viral DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
Antiviral activity against BKV Gardner ATCC VR837 infected in human WI38 cells assessed as reduction in viral DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
|
[PMID: 17893158]
|
WI-38
|
CC50 |
0.0476 μM
Compound: Colchicine
|
Cytotoxicity against human WI38 cells assessed as reduction in cellular DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
Cytotoxicity against human WI38 cells assessed as reduction in cellular DNA level preincubated for 2 hrs before viral infection measured after 7 days by real time PCR assay
|
[PMID: 17893158]
|
WM164
|
IC50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human WM164 cells after 48 hrs by SRB assay
Antiproliferative activity against human WM164 cells after 48 hrs by SRB assay
|
[PMID: 22608389]
|
WM164
|
IC50 |
0.03 μM
Compound: Colchicine
|
Antiproliferative activity against human WM164 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human WM164 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 21775150]
|
WM164
|
IC50 |
10.8 nM
Compound: Colchicine
|
Antiproliferative activity against human WM164 cells after 72 hrs by MTT assay
Antiproliferative activity against human WM164 cells after 72 hrs by MTT assay
|
[PMID: 31251599]
|
WM164
|
IC50 |
29 nM
Compound: Colchicine
|
Antiproliferative activity against human WM164 cells after 48 hrs by SRB assay
Antiproliferative activity against human WM164 cells after 48 hrs by SRB assay
|
[PMID: 22783954]
|
ZR-75-1
|
ED50 |
0.1 μg/mL
Compound: Colchicine
|
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
|
[PMID: 7528785]
|