Communesin B (Synonyms: (+)-Communesin B; Nomofungin)

Cat. No.: HY-N12904: FAQs
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Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium.

For research use only. We do not sell to patients.

Communesin B Chemical Structure

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Description

Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
L-428	ED₅₀	> 20 μg/mL Compound: 1	Antiproliferative activity against human L428 cells after 48 hrs by MTT assay Antiproliferative activity against human L428 cells after 48 hrs by MTT assay	[PMID: 14738391]
MOLT-3	ED₅₀	8.1 μg/mL Compound: 1	Antiproliferative activity against human MOLT3 cells after 48 hrs by MTT assay Antiproliferative activity against human MOLT3 cells after 48 hrs by MTT assay	[PMID: 14738391]
NAMALVA	ED₅₀	9.9 μg/mL Compound: 1	Antiproliferative activity against human NAMALWA cells after 48 hrs by MTT assay Antiproliferative activity against human NAMALWA cells after 48 hrs by MTT assay	[PMID: 14738391]
SUP-B15	ED₅₀	7.2 μg/mL Compound: 1	Antiproliferative activity against human SUP-B15 cells after 48 hrs by MTT assay Antiproliferative activity against human SUP-B15 cells after 48 hrs by MTT assay	[PMID: 14738391]
THP-1	ED₅₀	11.4 μg/mL Compound: 1	Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay	[PMID: 14738391]
U-937	ED₅₀	10.4 μg/mL Compound: 1	Antiproliferative activity against human U937 cells after 48 hrs by MTT assay Antiproliferative activity against human U937 cells after 48 hrs by MTT assay	[PMID: 14738391]

Molecular Weight

508.65

Formula

C₃₂H₃₆N₄O₂

CAS No.

148439-46-7

SMILES

CN1[C@]2([H])[C@]34[C@@]5(C6=CC=CC=C6N2)[C@@](N(CC5)C(/C=C/C=C/C)=O)([H])[N@@]([C@@]([C@]7([H])C(C)(O7)C)([H])C8=C4C1=CC=C8)CC3

Structure Classification

Initial Source

Microorganisms

marine alga Enteromorpha intestinalis

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Numata A, et al. Communesins, cytotoxic metabolites of a fungus isolated from a marine alga[J]. Tetrahedron Letters, 1993, 34(14): 2355-2358.

Communesin B Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Communesin B148439-46-7(+)-Communesin B NomofunginOthersPenicilliumP-388 cellsInhibitorinhibitorinhibit

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Communesin B (Synonyms: (+)-Communesin B; Nomofungin)

Communesin B Related Antibodies

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Communesin B Related Classifications

Molarity Calculator

Dilution Calculator