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  4. Coumarin boronic acid

Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification.

For research use only. We do not sell to patients.

Coumarin boronic acid Chemical Structure

Coumarin boronic acid Chemical Structure

CAS No. : 1357078-03-5

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5 mg USD 75 In-stock
10 mg USD 120 In-stock
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Coumarin boronic acid Related Antibodies

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Description

Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification[1].

Molecular Weight

189.96

Formula

C9H7BO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O1)C=CC2=C1C=C(B(O)O)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (438.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2643 mL 26.3213 mL 52.6427 mL
5 mM 1.0529 mL 5.2643 mL 10.5285 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.2643 mL 26.3213 mL 52.6427 mL 131.6066 mL
5 mM 1.0529 mL 5.2643 mL 10.5285 mL 26.3213 mL
10 mM 0.5264 mL 2.6321 mL 5.2643 mL 13.1607 mL
15 mM 0.3510 mL 1.7548 mL 3.5095 mL 8.7738 mL
20 mM 0.2632 mL 1.3161 mL 2.6321 mL 6.5803 mL
25 mM 0.2106 mL 1.0529 mL 2.1057 mL 5.2643 mL
30 mM 0.1755 mL 0.8774 mL 1.7548 mL 4.3869 mL
40 mM 0.1316 mL 0.6580 mL 1.3161 mL 3.2902 mL
50 mM 0.1053 mL 0.5264 mL 1.0529 mL 2.6321 mL
60 mM 0.0877 mL 0.4387 mL 0.8774 mL 2.1934 mL
80 mM 0.0658 mL 0.3290 mL 0.6580 mL 1.6451 mL
100 mM 0.0526 mL 0.2632 mL 0.5264 mL 1.3161 mL
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Coumarin boronic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Coumarin boronic acid1357078-03-5Fluorescent DyeFluorescent compoundsCOHCBAreal-time monitoringInhibitorinhibitorinhibit

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