Boronic Acid Compound Library

Cat. No.: HY-L167

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Boric acid is a stable and usually non-toxic group widely used in modern synthesis to form C-C and C-heteroatom bonds. Boric acid exhibits exquisite reversible coordination characteristics and can be explored as a molecular construction tool, with specific mechanisms for controlling the structure and biological characteristics of bioconjugates. Boric acid has various activities, such as anticancer, antibacterial, and antiviral activities. In drugs, boric acid mainly exists in the form of arylboronic acid. In addition to this form, heterocycles containing boric acid, such as pyridine, pyrrole, and indole derivatives, are also very useful in pharmaceutical chemistry. Molecular modification by introducing boric acid groups into bioactive molecules has been shown to alter selectivity, physicochemical, and pharmacokinetic characteristics, and improve existing activity.

MCE designs a unique collection of 147 boronic acid compounds. It is a good tool to be used for research on cancer and other diseases.

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Product Details
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Description & Advantages

• A unique collection of 147 boronic acid compounds for high throughput screening (HTS) and high content screening (HCS).

• A useful tool for cancer and other diseases research.

• Structurally diverse, medicinally active and cell permeable.

• Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

• More detailed compound information with structure, IC50, and other chemical & biological data.

• High purity and quality validated by NMR and LC/MS.

Product Details

Formulation:

A collection of 147 boronic acid compounds supplied as pre-dissolved Solutions or Solid

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

Biochemical Assay Reagents (109)

Proteasome (8)

Arginase (6)

Apoptosis (5)

Dipeptidyl Peptidase (3)

Phosphodiesterase (PDE) (3)

Autophagy (2)

Bacterial (2)

CXCR (2)

FAP (2)

NF-κB (2)

c-Myc (1)

Carbonic Anhydrase (1)

FAAH (1)

Fluorescent Dye (1)

NOD-like Receptor (NLR) (1)

PAI-1 (1)

Protein Arginine Deiminase (1)

ROCK (1)

SARS-CoV (1)

Ser/Thr Protease (1)

Sirtuin (1)

STAT (1)

Others (3)

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Plate Map
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