Coumarin-d₆ 

Coumarin-d₆ is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Coumarin (1-10 mg/kg; p.o.) shows an antinociceptive effect in a dose-dependent manner in the acetic acid-induced writhing test^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

152.18

C₉D₆O₂

116295-83-1

91-64-5

O=C1C([2H])=C([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2O1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Park SH, et al. Antinociceptive profiles and mechanisms of orally administered coumarin in mice. Biol Pharm Bull. 2013;36(6):925-30.  [Content Brief]

  [3]. enugopala KN, et al. Review on natural coumarin lead compounds for their pharmacological activity. Biomed Res Int. 2013;2013:963248.  [Content Brief]