1. Membrane Transporter/Ion Channel
  2. CRM1
  3. CRM1 degrader 1

CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer.

For research use only. We do not sell to patients.

CRM1 degrader 1 Chemical Structure

CRM1 degrader 1 Chemical Structure

CAS No. : 2986647-41-8

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Description

CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer[1].

Molecular Weight

260.33

Formula

C16H20O3

CAS No.
SMILES

CC1=CC(OC[C@H]2CC=CC(O2)=O)=C(C=C1)C(C)C

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CRM1 degrader 1
Cat. No.:
HY-146384
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