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  4. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)  (Synonyms: c(RGDfE))

Cat. No.: HY-P5021 Purity: 99.86%
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Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) (c(RGDfE)) is a cyclic RGD peptide that serves as a conjugated multifunctional nanodrug delivery system to target Gemcitabine to pancreatic cancer cells. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) can be used in cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) Chemical Structure

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) Chemical Structure

CAS No. : 756500-22-8

Size Price Stock Quantity
5 mg USD 160 In-stock
10 mg USD 256 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) Related Antibodies

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Description

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) (c(RGDfE)) is a cyclic RGD peptide that serves as a conjugated multifunctional nanodrug delivery system to target Gemcitabine to pancreatic cancer cells. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) can be used in cancer research[1].

Molecular Weight

604.61

Formula

C26H36N8O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cyclo(Arg-Gly-Asp-{d-Phe}-Glu)
Sequence Shortening

Cyclo(RGD-{d-Phe}-E)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (8.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6540 mL 8.2698 mL 16.5396 mL
5 mM 0.3308 mL 1.6540 mL 3.3079 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6540 mL 8.2698 mL 16.5396 mL 41.3490 mL
5 mM 0.3308 mL 1.6540 mL 3.3079 mL 8.2698 mL
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Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)756500-22-8c(RGDfE)Biochemical Assay ReagentsGemcitabinecancertumorRGDnanodrug deliveryInhibitorinhibitorinhibit

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