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  6. Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)  (Synonyms: Azido-c(RGDyK))

Cat. No.: HY-P5025 Purity: 99.16%
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Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [18F]FPyKYNE-c(RGDyK).

For research use only. We do not sell to patients.

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Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) Chemical Structure

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) Chemical Structure

CAS No. : 1392269-21-4

Size Price Stock Quantity
1 mg USD 180 In-stock
5 mg USD 450 In-stock
10 mg USD 650 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) Related Antibodies

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Description

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [18F]FPyKYNE-c(RGDyK)[1].

Molecular Weight

645.67

Formula

C27H39N11O8
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cyclo(Arg-Gly-Asp-{d-Tyr}-{ε-Azido-Nle})
Sequence Shortening

Cyclo(RGD-{d-Tyr}-{ε-Azido-Nle})
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (154.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5488 mL 7.7439 mL 15.4878 mL
5 mM 0.3098 mL 1.5488 mL 3.0976 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5488 mL 7.7439 mL 15.4878 mL 38.7195 mL
5 mM 0.3098 mL 1.5488 mL 3.0976 mL 7.7439 mL
10 mM 0.1549 mL 0.7744 mL 1.5488 mL 3.8719 mL
15 mM 0.1033 mL 0.5163 mL 1.0325 mL 2.5813 mL
20 mM 0.0774 mL 0.3872 mL 0.7744 mL 1.9360 mL
25 mM 0.0620 mL 0.3098 mL 0.6195 mL 1.5488 mL
30 mM 0.0516 mL 0.2581 mL 0.5163 mL 1.2906 mL
40 mM 0.0387 mL 0.1936 mL 0.3872 mL 0.9680 mL
50 mM 0.0310 mL 0.1549 mL 0.3098 mL 0.7744 mL
60 mM 0.0258 mL 0.1291 mL 0.2581 mL 0.6453 mL
80 mM 0.0194 mL 0.0968 mL 0.1936 mL 0.4840 mL
100 mM 0.0155 mL 0.0774 mL 0.1549 mL 0.3872 mL
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Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)1392269-21-4Azido-c(RGDyK)OtherspolypeptideInhibitorinhibitorinhibit

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