Cyclo(L-Phe-trans-4-OH-L-Pro)

Cat. No.: HY-N12513 Purity: 99.76%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Cyclo(L-Phe-trans-4-OH-L-Pro) is an antifungal peptides.

For research use only. We do not sell to patients.

Cyclo(L-Phe-trans-4-OH-L-Pro) Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cyclo(L-Phe-trans-4-OH-L-Pro) is an antifungal peptides^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	14.2 μg/mL Compound: 3	Inhibition of LPS-induced TNF-alpha production in mouse RAW264.7 cells pretreated with compound for 1 hr followed by addition of 1 ug/ml LPS for 6 hrs by ELISA Inhibition of LPS-induced TNF-alpha production in mouse RAW264.7 cells pretreated with compound for 1 hr followed by addition of 1 ug/ml LPS for 6 hrs by ELISA	[PMID: 26546220]

Molecular Weight

260.29

Formula

C₁₄H₁₆N₂O₃

CAS No.

118477-06-8

Appearance

Solid

Color

White to off-white

SMILES

O=C1N2[C@](C[C@H](C2)O)([H])C(N[C@H]1CC3=CC=CC=C3)=O

Structure Classification

Others

Initial Source

Microorganisms

Lactobacillus plantarum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (384.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8419 mL	19.2093 mL	38.4187 mL
5 mM	0.7684 mL	3.8419 mL	7.6837 mL
10 mM	0.3842 mL	1.9209 mL	3.8419 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.76%

Select Batch:

Data Sheet (268 KB) SDS (251 KB)

COA (248 KB) HNMR (263 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Katrin Ström, et al. Lactobacillus plantarum MiLAB 393 produces the antifungal cyclic dipeptides cyclo(L-Phe-L-Pro) and cyclo(L-Phe-trans-4-OH-L-Pro) and 3-phenyllactic acid. Appl Environ Microbiol. 2002 Sep;68(9):4322-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8419 mL	19.2093 mL	38.4187 mL	96.0467 mL
	5 mM	0.7684 mL	3.8419 mL	7.6837 mL	19.2093 mL
	10 mM	0.3842 mL	1.9209 mL	3.8419 mL	9.6047 mL
	15 mM	0.2561 mL	1.2806 mL	2.5612 mL	6.4031 mL
	20 mM	0.1921 mL	0.9605 mL	1.9209 mL	4.8023 mL
	25 mM	0.1537 mL	0.7684 mL	1.5367 mL	3.8419 mL
	30 mM	0.1281 mL	0.6403 mL	1.2806 mL	3.2016 mL
	40 mM	0.0960 mL	0.4802 mL	0.9605 mL	2.4012 mL
	50 mM	0.0768 mL	0.3842 mL	0.7684 mL	1.9209 mL
	60 mM	0.0640 mL	0.3202 mL	0.6403 mL	1.6008 mL
	80 mM	0.0480 mL	0.2401 mL	0.4802 mL	1.2006 mL
	100 mM	0.0384 mL	0.1921 mL	0.3842 mL	0.9605 mL