2. Natural Products
  3. Disease Research Fields Plants Steroids
  4. Liliaceae Other Diseases
  5. Veratrum californicum
  6. Cycloposine

Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound.

For research use only. We do not sell to patients.

Cycloposine Chemical Structure

Cycloposine Chemical Structure

CAS No. : 23185-94-6

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10 mg USD 1080 In-stock
25 mg USD 2050 In-stock
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Based on 1 publication(s) in Google Scholar

Cycloposine Related Antibodies

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  • Purity & Documentation

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Description

Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound[1].

In Vitro

Cycloposine producs fetal cyclopia and related central nervous system malformations in sheep[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cycloposine Related Antibodies
Molecular Weight

573.76

Formula

C33H51NO7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=C(C[C@@]2([H])[C@@]3([H])CC=C4[C@@]2(CC[C@@H](C4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)[C@@]3([H])CC[C@]16O[C@@]7([H])[C@](NC[C@H](C7)C)([H])[C@H]6C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 46.67 mg/mL (81.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7429 mL 8.7144 mL 17.4289 mL
5 mM 0.3486 mL 1.7429 mL 3.4858 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (252 KB) HNMR (433 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7429 mL 8.7144 mL 17.4289 mL 43.5722 mL
5 mM 0.3486 mL 1.7429 mL 3.4858 mL 8.7144 mL
10 mM 0.1743 mL 0.8714 mL 1.7429 mL 4.3572 mL
15 mM 0.1162 mL 0.5810 mL 1.1619 mL 2.9048 mL
20 mM 0.0871 mL 0.4357 mL 0.8714 mL 2.1786 mL
25 mM 0.0697 mL 0.3486 mL 0.6972 mL 1.7429 mL
30 mM 0.0581 mL 0.2905 mL 0.5810 mL 1.4524 mL
40 mM 0.0436 mL 0.2179 mL 0.4357 mL 1.0893 mL
50 mM 0.0349 mL 0.1743 mL 0.3486 mL 0.8714 mL
60 mM 0.0290 mL 0.1452 mL 0.2905 mL 0.7262 mL
80 mM 0.0218 mL 0.1089 mL 0.2179 mL 0.5447 mL
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Cycloposine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cycloposine23185-94-6OtherssteroidalalkaloidVeratrumcalifornicumteratogenicInhibitorinhibitorinhibit

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