1. Anti-infection
  2. Fungal Bacterial
  3. Cyclosporin C

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs=0.1-5 μg/ml).

For research use only. We do not sell to patients.

Cyclosporin C Chemical Structure

Cyclosporin C Chemical Structure

CAS No. : 59787-61-0

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1 mg USD 75 In-stock
5 mg USD 180 In-stock
10 mg USD 300 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs=0.1-5 μg/ml).

Molecular Weight

1218.61

Formula

C62H111N11O13

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]([C@](C(N[C@@](C(N(CC(N([C@H](C(N[C@H](C(N([C@H]1CC(C)C)C)=O)C(C)C)=O)CC(C)C)C)=O)C)=O)([H])[C@H](O)C)=O)([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)[C@H](C)C/C=C/C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (82.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8206 mL 4.1030 mL 8.2061 mL
5 mM 0.1641 mL 0.8206 mL 1.6412 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8206 mL 4.1030 mL 8.2061 mL 20.5152 mL
5 mM 0.1641 mL 0.8206 mL 1.6412 mL 4.1030 mL
10 mM 0.0821 mL 0.4103 mL 0.8206 mL 2.0515 mL
15 mM 0.0547 mL 0.2735 mL 0.5471 mL 1.3677 mL
20 mM 0.0410 mL 0.2052 mL 0.4103 mL 1.0258 mL
25 mM 0.0328 mL 0.1641 mL 0.3282 mL 0.8206 mL
30 mM 0.0274 mL 0.1368 mL 0.2735 mL 0.6838 mL
40 mM 0.0205 mL 0.1026 mL 0.2052 mL 0.5129 mL
50 mM 0.0164 mL 0.0821 mL 0.1641 mL 0.4103 mL
60 mM 0.0137 mL 0.0684 mL 0.1368 mL 0.3419 mL
80 mM 0.0103 mL 0.0513 mL 0.1026 mL 0.2564 mL
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Cyclosporin C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cyclosporin C
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