2. Metabolic Enzyme/Protease Anti-infection
  3. Cytochrome P450 Parasite
  4. Cyprocide-B

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.

For research use only. We do not sell to patients.

Cyprocide-B Chemical Structure

Cyprocide-B Chemical Structure

CAS No. : 49809-25-8

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Cyprocide-B Related Antibodies

Top Publications Citing Use of Products

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide[1].

In Vitro

Cyprocide-B (50 µM, 3 days) is a selective nematicide with broad-spectrum activity in plant-parasitic nematodes (PPNs), and is safer for zebrafish than Tioxazafen (HY-136240)[1].
Cyprocide-B (25 μM, 24 h) is bioactivated by CYP-35D1 to produce a reactive electrophile in C. elegans[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cyprocide-B Related Antibodies

Cell Viability Assay[1]

Cell Line: Human cells, fungi, plant beneficial rhizobacteria
Concentration: 50 µM
Incubation Time: 3 days
Result: Was relatively inactive against non-nematode phyla at the same concentration of killing nematodes in vitro.
In Vivo

Cyprocide-B (60 μM, 24 h) has potential utility in preventing root infestation by M. incognita in a soil environment[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

240.71

Formula

C10H9ClN2OS
CAS No.
SMILES

CCSC1=NN=C(C2=CC=C(Cl)C=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cyprocide-B Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyprocide-B49809-25-8Cytochrome P450ParasiteCYPsnematodeselectrophilic metaboliteC. elegansselective nematicideInhibitorinhibitorinhibit

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HY-163804
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