2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. CYY292

CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro.

For research use only. We do not sell to patients.

CYY292 Chemical Structure

CYY292 Chemical Structure

CAS No. : 2644673-04-9

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1 mg USD 61 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
5 mg USD 220 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
10 mg USD 350 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
25 mg USD 700 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
50 mg USD 1100 Get quote 6 - 8 weeks 6 - 8 weeks 5 - 7 weeks
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Based on 1 publication(s) in Google Scholar

CYY292 Related Antibodies

Top Publications Citing Use of Products

View All FGFR Isoform Specific Products:

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FGFR FGFR1 FGFR2 FGFR3 FGFR4 FGF21

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Description

CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1].

IC50 & Target

FGFR1[1]
Molecular Weight

444.53

Formula

C24H28N8O
CAS No.
SMILES

CN1CCN(C2=C(OC)C=C(NC3=NC(NC4=CC(NN=C5)=C5C=C4)=C(C)C=N3)C=C2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CYY292 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYY2922644673-04-9CYY 292CYY-292FGFRFibroblast growth factor receptorCell proliferationepithelial-mesenchymal transitionstem cell invasioncell migrationInhibitorinhibitorinhibit

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