2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. D-myo-Inositol 1,4,5-trisphosphate tripotassium

D-myo-Inositol 1,4,5-trisphosphate tripotassium  (Synonyms: Inositol 1,4,5-trisphosphate tripotassium; Ins(1,4,5)-P3 tripotassium)

Cat. No.: HY-150135B Purity: ≥98.0%
SDS COA Handling Instructions

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D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2).

For research use only. We do not sell to patients.

D-myo-Inositol 1,4,5-trisphosphate tripotassium Chemical Structure

D-myo-Inositol 1,4,5-trisphosphate tripotassium Chemical Structure

CAS No. : 141611-11-2

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1 mg USD 850 In-stock
5 mg USD 2125 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of D-myo-Inositol 1,4,5-trisphosphate tripotassium:

D-myo-Inositol 1,4,5-trisphosphate tripotassium Related Antibodies

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1 Publications Citing Use of MCE D-myo-Inositol 1,4,5-trisphosphate tripotassium

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Description

D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2)[1].

Molecular Weight

534.37

Formula

C6H12K3O15P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(O)(O[K])=O)OP(O)(O[K])=O)O)OP(O)(O[K])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (93.57 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8714 mL 9.3568 mL 18.7136 mL
5 mM 0.3743 mL 1.8714 mL 3.7427 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (252 KB)

COA (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8714 mL 9.3568 mL 18.7136 mL 46.7841 mL
5 mM 0.3743 mL 1.8714 mL 3.7427 mL 9.3568 mL
10 mM 0.1871 mL 0.9357 mL 1.8714 mL 4.6784 mL
15 mM 0.1248 mL 0.6238 mL 1.2476 mL 3.1189 mL
20 mM 0.0936 mL 0.4678 mL 0.9357 mL 2.3392 mL
25 mM 0.0749 mL 0.3743 mL 0.7485 mL 1.8714 mL
30 mM 0.0624 mL 0.3119 mL 0.6238 mL 1.5595 mL
40 mM 0.0468 mL 0.2339 mL 0.4678 mL 1.1696 mL
50 mM 0.0374 mL 0.1871 mL 0.3743 mL 0.9357 mL
60 mM 0.0312 mL 0.1559 mL 0.3119 mL 0.7797 mL
80 mM 0.0234 mL 0.1170 mL 0.2339 mL 0.5848 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-myo-Inositol 1,4,5-trisphosphate tripotassium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-myo-Inositol 1,4,5-trisphosphate tripotassium141611-11-2Inositol 1,4,5-trisphosphate tripotassiumIns(1,4,5)-P3 tripotassiumCalcium ChannelCa2+ channelsCa channelsPLC-delta 1phosphatidylcholinePIP2Ins(l,4,5)P3Inhibitorinhibitorinhibit

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